Jayakumar Vadakekolathu

About Jayakumar Vadakekolathu

Jayakumar Vadakekolathu, With an exceptional h-index of 18 and a recent h-index of 18 (since 2020), a distinguished researcher at Nottingham Trent University, specializes in the field of Cancer, Molecular biology, Proteomics, Gene expression, Immunology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Promoter methylation leads to Hepatocyte Nuclear Factor 4A loss and pancreatic cancer aggressiveness

A rapid method for generating transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells.

Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes

WU-NK-101 (W-NK), a Memory-like (ML) NK Cell, Naturally Overcomes Tumor Microenvironment (TME) Metabolic Challenges, Retaining Anti-Tumor Potency

Spatial proteomics reveals heterogeneity in neural markers underpinning high-fat diet-induced myopathy in male mice.

S129: ADOPTIVELY INFUSED MEMORY-LIKE (ML) NATURAL KILLER (NK) CELLS ELICIT ADAPTIVE IMMUNE RESPONSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML)

Spatially Resolved Transcriptomics Unveils Unique T-Cell Dysfunctional States and Prognostic Gene Expression Signatures in TP53-Mutated Acute Myeloid Leukemia

Escape from T-cell targeting immunotherapies in acute myeloid leukemia

Jayakumar Vadakekolathu Information

University

Position

___

Citations(all)

1177

Citations(since 2020)

1050

Cited By

352

hIndex(all)

18

hIndex(since 2020)

18

i10Index(all)

27

i10Index(since 2020)

24

Email

University Profile Page

Google Scholar

Jayakumar Vadakekolathu Skills & Research Interests

Cancer

Molecular biology

Proteomics

Gene expression

Immunology

Top articles of Jayakumar Vadakekolathu

Title

Journal

Author(s)

Publication Date

Promoter methylation leads to Hepatocyte Nuclear Factor 4A loss and pancreatic cancer aggressiveness

Gastro Hep Advances

Maria Hatziapostolou

Marina Koutsioumpa

Abed M Zaitoun

Christos Polytarchou

Mouad Edderkaoui

...

2024/4/24

A rapid method for generating transplantable and biologically responsive colonic tissue from human induced pluripotent stem cells.

bioRxiv

William Dalleywater

Alexander V Predeus

Batuhan Cakir

Pavel Mazin

Jayakumar Vadakekolathu

...

2023

Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes

Diabetic Medicine

Forough Torabi

Jayakumar Vadakekolathu

Rebecca Wyatt

Pia Leete

Melissa A Tombs

...

2023/9

WU-NK-101 (W-NK), a Memory-like (ML) NK Cell, Naturally Overcomes Tumor Microenvironment (TME) Metabolic Challenges, Retaining Anti-Tumor Potency

Blood

Nupur Bhatnagar

Vincent Petit

Jayakumar Vadakekolathu

Christian Pinset

Nitin Mahajan

...

2023/11/28

Spatial proteomics reveals heterogeneity in neural markers underpinning high-fat diet-induced myopathy in male mice.

bioRxiv

Lydia Hardowar

Jayakumar Vadakekolathu

Sergio Rutella

Richard Hulse

Craig L Doig

2023

S129: ADOPTIVELY INFUSED MEMORY-LIKE (ML) NATURAL KILLER (NK) CELLS ELICIT ADAPTIVE IMMUNE RESPONSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA (AML)

HemaSphere

Sergio Rutella

Amanda Cashen

John Muth

Jayakumar Vadakekolathu

Laura Arthur

...

2023/8/1

Spatially Resolved Transcriptomics Unveils Unique T-Cell Dysfunctional States and Prognostic Gene Expression Signatures in TP53-Mutated Acute Myeloid Leukemia

Blood

Jayakumar Vadakekolathu

Heidi Altmann

Manja Wobus

Malte von Bonin

Marc Schmitz

...

2023/11/28

Escape from T-cell targeting immunotherapies in acute myeloid leukemia

Jayakumar Vadakekolathu

Sergio Rutella

2023/7/22

Adoptively Infused Memory-like Natural Killer Cells Impact Adaptive Immune Responses in Patients with Acute Myeloid Leukemia

Blood

Sergio Rutella

Jayakumar Vadakekolathu

Amanda F Cashen

Nitin Mahajan

Yanira Ruiz-Heredia

...

2023/11/28

Canonical and truncated transglutaminase-2 regulate mucin-1 expression and androgen independency in prostate cancer cell lines

Cell Death & Disease

Adeola Grace Atobatele

Elisa Tonoli

Jayakumar Vadakekolathu

Maria Pia Savoca

Melissa Barr

...

2023/5/9

WU-NK-101 (W-NK), a Memory-like (ML) NK Cell, Intrinsically Overcomes Factors Restricting Adoptive Cell Therapy (ACT) in Acute Myeloid Leukemia (AML)

Blood

Sergio Rutella

John Muth

Jayakumar Vadakekolathu

Tom Leedom

Alex Hamil

...

2023/11/28

WU-NK-101, an enhanced memory natural killer (NK) cell therapy, with cetuximab (Ctx) for the treatment of advanced colorectal cancer (CRC).

John Muth

Tom Leedom

Alexander Hamil

Y Zhou

L Luukkonen

...

2023/2/1

Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study

British Journal of Haematology

Darina Ocadlikova

Federico Lussana

Nicola Fracchiolla

Massimiliano Bonifacio

Lidia Santoro

...

2023/11

T Cell/Natural Killer (NK) Cell Transcriptional Profiles Are Associated with Response to Gilteritinib in FLT3-Mutated Acute Myeloid Leukemia

Blood

Jacopo Nanni

Jayakumar Vadakekolathu

Lorenza Bandini

Samantha Bruno

Letizia Zannoni

...

2023/12/1

A Mutated Prostatic Acid Phosphatase (PAP) Peptide-Based Vaccine Induces PAP-Specific CD8+ T Cells with Ex Vivo Cytotoxic Capacities in HHDII/DR1 …

Cancers

Pauline Le Vu

Jayakumar Vadakekolathu

Sarra Idri

Holly Nicholls

Manon Cavaignac

...

2022/4/13

Gene expression profiling of FFPE samples: a titration test

Technology in Cancer Research & Treatment

Harshitha Shobha Manjunath

Moza Al Khulaifi

Heba Sidahmed

Adham Ammar

Jayakumar Vadakekolathu

...

2022/11

An IDO1-related immune gene signature predicts overall survival in acute myeloid leukemia

Blood Advances

Simone Ragaini

Sarah Wagner

Giovanni Marconi

Sarah Parisi

Chiara Sartor

...

2022/1/11

Nanobugs as drugs: bacterial derived nanomagnets enhance tumor targeting and oncolytic activity of HSV‐1 virus

Small

Faith HN Howard

Haider Al‐Janabi

Priya Patel

Katie Cox

Emily Smith

...

2022/4

Immune dysfunction signatures predict outcomes and define checkpoint blockade–unresponsive microenvironments in acute myeloid leukemia

The Journal of Clinical Investigation

Sergio Rutella

Jayakumar Vadakekolathu

Francesco Mazziotta

Stephen Reeder

Tung-On Yau

...

2022/11/1

Hyperactive neutrophil chemotaxis contributes to anti‐tumor necrosis factor‐α treatment resistance in inflammatory bowel disease

Journal of Gastroenterology and Hepatology

Tung On Yau

Jayakumar Vadakekolathu

Gemma Ann Foulds

Guodong Du

Benjamin Dickins

...

2022/3

See List of Professors in Jayakumar Vadakekolathu University(Nottingham Trent University)

Co-Authors

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