Jason E. Gestwicki
University of California, San Francisco
H-index: 84
North America-United States
Top articles of Jason E. Gestwicki
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
A missense mutation in the Hspa8 gene encoding heat shock cognate protein 70 causes neuroaxonal dystrophy in rats | Frontiers in Neuroscience | Miyuu Tanaka Ryoko Fujikawa Takahiro Sekiguchi Jason Hernandez Oleta T Johnson | 2024/2/6 |
Stress Biology: Complexity and Multifariousness in Health and Disease | Cell Stress and Chaperones | Matthias P Mayer Laura Blair Gregory L Blatch Thiago J Borges Ahmed Chadli | 2024/2/3 |
Plexin D1 emerges as a novel target in the development of neural lineage plasticity in treatment-resistant prostate cancer | Chengfei Liu Bo Chen Pengfei Xu Joy Yang Christopher Nip | 2024/3/27 | |
J-domain proteins: From molecular mechanisms to diseases | Cell Stress and Chaperones | Jaroslaw Marszalek Paolo De Los Rios Douglas Cyr Matthias P Mayer Vasista Adupa | 2024/2/1 |
Dual targeting of HSP70 and AURKA improves treatment in neuroendocrine prostate cancer | Cancer Research | Pengfei Xu Joy C Yang Bo Chen Shu Ning Leyi Wang | 2024/3/22 |
Plasmodium falciparum heat shock proteins as anti-malarial drug targets: An update | Tanveer Ahmad Bushra A Alhammadi Shaikha Y Almaazmi Sahar Arafa Gregory L Blatch | 2024/3/20 | |
A screening platform for fluorescent dyes that recognize tau fibrils in situ | Biophysical Journal | Emma C Carroll Hyunjun Yang Kelly Montgomery Annemarie F Charvat Anthony Yung | 2024/2/8 |
An unbiased screen identified the Hsp70-BAG3 complex as a regulator of myosin-binding protein C3 | Basic to Translational Science | Andrea D Thompson Marcus J Wagner Juliani Rodriguez Alok Malhotra Steve Vander Roest | 2023/9/1 |
Interaction with the membrane-anchored protein CHIC2 constrains the ubiquitin ligase activity of CHIP | bioRxiv | Matthew D Callahan Molly Hodul Emma C Carroll Matthew Ravalin Cory M Nadel | 2023 |
Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry | bioRxiv | Taiasean Wu C Yu Joshua Arundhati Suresh Zachary J Gale-Day Matthew G Alteen | 2023/1/28 |
PD04-09 COMBINATION TREATMENT WITH HSP70/STUB1 MODULATOR AND ENZALUTAMIDE YIELDS SYNERGISTIC ACTIVITY IN ADVANCED PROSTATE CANCER | The Journal of Urology | Pengfei Xu Joy C Yang Bo Chen Christopher Nip Shu Ning | 2023/4 |
Phosphorylation of a Cleaved Tau Proteoform at a Single Residue Inhibits Binding to the E3 Ubiquitin Ligase, CHIP | bioRxiv | Cory M Nadel Kristin Wucherer Abby Oehler Aye C Thwin Koli Basu | 2023 |
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2 | Proceedings of the National Academy of Sciences | Stefan Gahbauer Galen J Correy Marion Schuller Matteo P Ferla Yagmur Umay Doruk | 2023/1/10 |
A Comprehensive Enumeration of the Human Proteostasis Network. 2. Components of the Autophagy-Lysosome Pathway | BioRxiv | Proteostasis Consortium Overall coordination Suzanne Elsasser Lisa P Elia Richard I Morimoto | 2022/9/2 |
The E3 ubiquitin ligase, CHIP/STUB1, inhibits aggregation of phosphorylated proteoforms of microtubule-associated protein tau (MAPT) | Journal of molecular biology | Cory M Nadel Aye C Thwin Matthew Callahan Kanghyun Lee Emily Connelly | 2023/6/1 |
N-myc–Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma | Cancer research | Duygu Kuzuoglu-Ozturk Ozlem Aksoy Christin Schmidt Robin Lea Jon D Larson | 2023/1/4 |
Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models | Pharmacological research | Pengfei Xu Joy C Yang Shu Ning Bo Chen Christopher Nip | 2023/3/1 |
Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly | bioRxiv | Julian R Braxton Hao Shao Eric Tse Jason E Gestwicki Daniel R Southworth | 2023/5/15 |
Cholesterol Dysregulation Drives Seed-Dependent Tau Aggregation in Patient Stem Cell-Derived Models of Tauopathy | bioRxiv | Morrie Lam Szu-Yu Kuo Surya Reis Jason E Gestwicki M Catarina Silva | 2023 |
Protocol for performing and optimizing differential scanning fluorimetry experiments | STAR protocols | Taiasean Wu Michael Hornsby Lawrence Zhu C Yu Joshua Kevan M Shokat | 2023/12/15 |
Co-Authors
