Jannie Borst

Jannie Borst

Universiteit Leiden

H-index: 87

Europe-Netherlands

About Jannie Borst

Jannie Borst, With an exceptional h-index of 87 and a recent h-index of 38 (since 2020), a distinguished researcher at Universiteit Leiden, specializes in the field of T cell immunity to cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors

PD-1 and CTLA-4 blockade promote CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice

Treg cells from human blood differentiate into non-lymphoid tissue-resident effector cells upon TNFR2 costimulation

Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

Identifying the nature of Tregs in human pregnancy

CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment

Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer.

Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer

Jannie Borst Information

University

Position

Medical School

Citations(all)

23425

Citations(since 2020)

6285

Cited By

19016

hIndex(all)

87

hIndex(since 2020)

38

i10Index(all)

184

i10Index(since 2020)

99

Email

University Profile Page

Universiteit Leiden

Google Scholar

View Google Scholar Profile

Jannie Borst Skills & Research Interests

T cell immunity to cancer

Top articles of Jannie Borst

Title

Journal

Author(s)

Publication Date

CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors

Cellular & Molecular Immunology

Xin Lei

Daniël C de Groot

Marij JP Welters

Tom de Wit

Ellen Schrama

...

2024/2/21

PD-1 and CTLA-4 blockade promote CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice

The Journal of Clinical Investigation

Elselien Frijlink

Douwe MT Bosma

Julia Busselaar

Thomas W Battaglia

Mo D Staal

...

2024/2/13

Treg cells from human blood differentiate into non-lymphoid tissue-resident effector cells upon TNFR2 costimulation

JCI insight

Mark Mensink

Lotte J Verleng

Ellen Schrama

George MC Janssen

Rayman TN Tjokrodirijo

...

2024/1/30

Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

Cell Reports Medicine

Jenny Sprooten

Isaure Vanmeerbeek

Angeliki Datsi

Jannes Govaerts

Stefan Naulaerts

...

2024/1/16

Identifying the nature of Tregs in human pregnancy

Journal of Reproductive Immunology

Lotte J Verleng

Mark Mensink

Ellen Schrama

Hanneke Kapsenberg

Juliette Krop

...

2023/9/1

CD4+ helper T cells endow cDC1 with cancer-impeding functions in the human tumor micro-environment

Nature Communications

Xin Lei

Indu Khatri

Tom de Wit

Iris de Rink

Marja Nieuwland

...

2023/1/13

Immune checkpoints targeting dendritic cells for antibody-based modulation in cancer.

Xin Lei

Yizhi Wang

Chayenne Broens

Jannie Borst

Yanling Xiao

2023/8/12

Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer

Science Translational Medicine

Stefan Naulaerts

Angeliki Datsi

Daniel M Borras

Asier Antoranz Martinez

Julie Messiaen

...

2023/4/12

N-terminal acetylation can stabilize proteins independent of their ubiquitination

Scientific Reports

Bert van de Kooij

Evert de Vries

Rogier W Rooswinkel

George MC Janssen

Frédérique K Kok

...

2023/4/1

A lymph node-to-tumour PDL1+macrophage circuit antagonizes dendritic cell immunotherapy

bioRxiv

Jenny Sprooten

Isaure Vanmeerbeek

Angeliki Datsi

Jannes Govaerts

Daniel M Borràs

...

2023/3/15

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

Oncoimmunology

Raquel S Laureano

Jenny Sprooten

Isaure Vanmeerbeerk

Daniel M Borras

Jannes Govaerts

...

2022/12/31

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4+ regulatory T cells

Scientific reports

Mark Mensink

Ellen Schrama

Eloy Cuadrado

Derk Amsen

Sander de Kivit

...

2022/11/24

TNFR2 costimulation differentially impacts regulatory and conventional CD4+ T-cell metabolism

Mark Mensink

Thi Ngoc Minh Tran

Esther A Zaal

Ellen Schrama

Celia R Berkers

...

2022/6/30

Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy

Journal for Immunotherapy of Cancer

Lars Guelen

Thierry O Fischmann

Jerelyn Wong

Smita Mauze

Marco Guadagnoli

...

2022

Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy

BioRxiv

Stefan Naulaerts

Daniel M Borras

Asier Antoranz Martinez

Julie Messiaen

Yannick Van Herck

...

2021/11/22

Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells

Cell reports

Elisa Matas-Rico

Elselien Frijlink

Irene van der Haar Àvila

Apostolos Menegakis

Maaike van Zon

...

2021/11/16

Clinically applicable CD34+-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses

Cancer Immunology, Immunotherapy

Jesper van Eck van der Sluijs

Diede van Ens

Soley Thordardottir

Denise Vodegel

Inge Hermens

...

2021/11

Mechanism of action of PD‐1 receptor/ligand targeted cancer immunotherapy

Jannie Borst

Julia Busselaar

Douwe MT Bosma

Ferry Ossendorp

2021/8

Flagellin/TLR5 stimulate myeloid progenitors to enter lung tissue and to locally differentiate into macrophages

Frontiers in Immunology

Xin Lei

Jara Palomero

Iris De Rink

Tom De Wit

Martijn Van Baalen

...

2021/3/19

GPA33: A marker to identify stable human regulatory T cells

The Journal of Immunology

Rianne Opstelten

Sander de Kivit

Manon C Slot

Maartje van den Biggelaar

Dorota Iwaszkiewicz-Grześ

...

2020/6/15

See List of Professors in Jannie Borst University(Universiteit Leiden)

Co-Authors

H-index: 85
Peter J. Peters

Peter J. Peters

Universiteit Maastricht

H-index: 56
Stephen Tait

Stephen Tait

University of Glasgow

H-index: 25
Jonathan Coquet

Jonathan Coquet

Karolinska Institutet

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