Jan Tytgat
Katholieke Universiteit Leuven
H-index: 60
Europe-Belgium
Top articles of Jan Tytgat
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue | FEBS letters | Iana I Zavarzina Alexey I Kuzmenkov Nikita A Dobrokhotov Ekaterina E Maleeva Yuliya V Korolkova | 2024/4/2 |
Attenuation of Nicotine Effects on A549 Lung Cancer Cells by Synthetic α7 nAChR Antagonists APS7-2 and APS8-2 | Marine drugs | Ahmad Joukhan Veno Kononenko Tadeja Bele Marija Sollner Dolenc Steve Peigneur | 2024/3/26 |
The Sobering Sting: Oleoyl Serotonin Is a Novel Stephanoconus Snail Venom-Derived Antagonist of Cannabinoid Receptors That Counteracts Learning and … | Biomedicines | Dongchen An Guilherme Salgado Carrazoni Ben-Hur Souto das Neves Rudi D’Hooge Steve Peigneur | 2024/2/18 |
ScrepYard: An online resource for disulfide‐stabilized tandem repeat peptides | Protein Science | Junyu Liu Michael Maxwell Thom Cuddihy Theo Crawford Madeline Bassetti | 2023/2 |
Methionine-isoleucine dichotomy at a key position in scorpion toxins inhibiting voltage-gated potassium channels | Toxicon | Alexey I Kuzmenkov Andrei M Gigolaev Ernesto L Pinheiro-Junior Steve Peigneur Jan Tytgat | 2023/8/1 |
Immunosuppressive effects of new thiophene-based KV1. 3 inhibitors | European journal of medicinal chemistry | Špela Gubič Alberto Montalbano Cesare Sala Andrea Becchetti Louise Antonia Hendrickx | 2023/11/5 |
Structural Optimization of an α-Hairpinin Blocking Potassium Channels KV1.3 | Journal of Evolutionary Biochemistry and Physiology | AM Gigolaev VM Tabakmakher S Peigneur J Tytgat AA Vassilevski | 2023/1 |
Design of New Potent and Selective Thiophene-Based K (V) 1.3 Inhibitors and Their Potential for Anticancer Activity (vol 14, 2595, 2022) | Cancers | Špela Gubič Louise Antonia Hendrickx Xiaoyi Shi Žan Toplak Štefan Možina | 2022/5/24 |
New aryl and acylsulfonamides as state-dependent inhibitors of Nav1. 3 voltage-gated sodium channel | European journal of medicinal chemistry | Nace Zidar Tihomir Tomašič Danijel Kikelj Martina Durcik Jan Tytgat | 2023/10/5 |
Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14, 2595 | Cancers | Špela Gubič Louise Antonia Hendrickx Xiaoyi Shi Žan Toplak Štefan Možina | 2023/5/26 |
Targeting cannabinoid receptor signaling for drug discovery and characterization: A focus on CB1 and CB2 cannabinoid receptors and GIRK1/GIRK2 potassium channels | Dongchen An Jan Tytgat Steve Peigneur | 2023/9/5 | |
AgTx2-GFP, Fluorescent Blocker Targeting Pharmacologically Important Kv1.x (x = 1, 3, 6) Channels | Toxins | Alexandra L Primak Nikita A Orlov Steve Peigneur Jan Tytgat Anastasia A Ignatova | 2023/3/18 |
Bombé, an undetermined substance that caused an outbreak of illicit drug use in Kinshasa, Democratic Republic of the Congo | Clinical Toxicology | Paul Musa Obadia Patrice Milambo Kapia Arne Bonneure Radu-Corneliu Duca Matteo Creta | 2023/12/2 |
A scorpion toxin affecting sodium channels shows double cis–trans isomerism | FEBS letters | Konstantin S Mineev Mikhail A Chernykh Vladislav V Motov Daria A Prudnikova Daniil M Pavlenko | 2023/9 |
Structure-Function Studies of Sponge-Derived Compounds on the Cardiac CaV3.1 Channel | International journal of molecular sciences | Anne-Sophie Depuydt Piyush A Patel Žan Toplak Chinmaya Bhat Manuela Voráčová | 2023/2/8 |
Structure-function relationship of new peptides activating human Nav1. 1 | Biomedicine & Pharmacotherapy | Ludivine Lopez Stephan De Waard Hervé Meudal Cécile Caumes Kuldip Khakh | 2023/9/1 |
Histamine Receptors: Ex Vivo Functional Studies Enabling the Discovery of Hits and Pathways | Membranes | Andrea Seldeslachts Steve Peigneur Jan Tytgat | 2023/12/2 |
Apamin structure and pharmacology revisited | Frontiers in Pharmacology | Alexey I Kuzmenkov Steve Peigneur Joshua A Nasburg Konstantin S Mineev Maxim V Nikolaev | 2022/9/16 |
Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment | Žan Toplak Louise A Hendrickx Reham Abdelaziz Xiaoyi Shi Steve Peigneur | 2022/1 | |
Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity | Casey A Schmidt Ira Cooke David T Wilson David J Miller Steve Peigneur | 2022/7/13 |
