Jan Johansson
Karolinska Institutet
H-index: 77
Europe-Sweden
Top articles of Jan Johansson
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain | Nature Communications | Rakesh Kumar Tanguy Le Marchand Laurène Adam Raitis Bobrovs Gefei Chen | 2024/2/1 |
Spiders Use Structural Conversion of Globular Amyloidogenic Domains to Make Strong Silk Fibers | Advanced Functional Materials | Xingmei Qi Han Wang Kezhen Wang Yu Wang Axel Leppert | 2024 |
分子伴侣治疗阿尔茨海默病的潜力 | 中国神经再生研究 (英文版) | Gefei Chen Jan Johansson | 2024/11/15 |
Potential of molecular chaperones for treating Alzheimer’s disease | Neural Regeneration Research | Gefei Chen Jan Johansson | 2024/11/1 |
Treatment with BRICHOS domain helps to clarify issues with Alzheimer mouse models | EMBO Molecular Medicine | Jan Johansson | 2024/3/13 |
The anti-amyloid BRICHOS domain regulates tau protein liquid-liquid phase separation and inhibits tau fibrillation associated with Alzheimer’s disease | Biophysical Journal | Cecilia Mörman Axel Leppert Jan Johansson Jinghui Luo Axel Abelein | 2024/2/8 |
Amyloid inhibition by molecular chaperones in vitro can be translated to Alzheimer's pathology in vivo | Axel Abelein Jan Johansson | 2023 | |
Spider Silk Protein Forms Amyloid‐Like Nanofibrils through a Non‐Nucleation‐Dependent Polymerization Mechanism | Small | Xingmei Qi Yu Wang Hairui Yu Ruifang Liu Axel Leppert | 2023/11 |
Tuneable Recombinant Spider Silk Protein Hydrogels for Drug Release and 3D Cell Culture | Advanced Functional Materials | Tina Arndt Urmimala Chatterjee Olga Shilkova Juanita Francis Johan Lundkvist | 2023/5/26 |
A “grappling hook” interaction connects self-assembly and chaperone activity of Nucleophosmin 1 | PNAS nexus | Mihkel Saluri Axel Leppert Genis Valentin Gese Cagla Sahin Dilraj Lama | 2023/2 |
Identification of glycolytic proteins as binding partners of Bri2 BRICHOS domain | Journal of Pharmaceutical and Biomedical Analysis | Helene Tigro Makoto Shimozawa Per Nilsson Alexey Lyashkov Mohammed Khadeer | 2023/8/5 |
Misfolded alpha-synuclein detection by RT-QuIC in dementia with lewy bodies: a systematic review and meta-analysis | Carmen Peña-Bautista Rakesh Kumar Miguel Baquero Jan Johansson Consuelo Cháfer-Pericás | 2023/5/17 | |
Intravenous treatment with a molecular chaperone designed against β-amyloid toxicity improves Alzheimer’s disease pathology in mouse models | MOLECULAR THERAPY | Manchanda Shaf fi Lorena Galan-Acosta Axel Abelein Simone Tambaro | 2023/2/1 |
Bri2 brichos domain for delivery of proteins into cns neurons | 2023/7/13 | ||
Synthetic surfactants | Fernando Moya Tore Curstedt Jan Johansson David Sweet | 2023/12/1 | |
Compound and method for treatment of alzheimer's disease | 2023/1/5 | ||
Short hydrophobic loop motifs in BRICHOS domains determine chaperone activity against amorphous protein aggregation but not against amyloid formation | Communications Biology | Gefei Chen Axel Leppert Helen Poska Harriet E Nilsson Carlos Piedrafita Alvira | 2023/5/8 |
Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS | bioRxiv | Laurène Adam Rakesh Kumar Luis Enrique Arroyo-Garcia Willem Hendrik Molenkamp Jan Stanislaw Nowak | 2023 |
Synthetic surfactant with a combined SP-B and SP-C analogue is efficient in rabbit models of adult and neonatal respiratory distress syndrome | Translational Research | Pavol Mikolka Nina Kronqvist Marie Haegerstrand-Björkman Kristaps Jaudzems Petra Kosutova | 2023/12/1 |
A new kid in the folding funnel: Molecular chaperone activities of the BRICHOS domain | Axel Leppert Helen Poska Michael Landreh Axel Abelein Gefei Chen | 2023/6 |
