James S. Fraser
University of California, San Francisco
H-index: 52
North America-United States
Top articles of James S. Fraser
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2 | Proceedings of the National Academy of Sciences | Stefan Gahbauer Galen J Correy Marion Schuller Matteo P Ferla Yagmur Umay Doruk | 2023/1/10 |
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography | Nature Chemistry | Alexander M Wolff Eriko Nango Iris D Young Aaron S Brewster Minoru Kubo | 2023/11 |
Molecular-dynamics simulation methods for macromolecular crystallography | Acta Crystallographica Section D: Structural Biology | David C Wych Phillip C Aoto Lily Vu Alexander M Wolff David L Mobley | 2023/1/1 |
Large language models generate functional protein sequences across diverse families | Nature Biotechnology | Ali Madani Ben Krause Eric R Greene Subu Subramanian Benjamin P Mohr | 2023/8 |
Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel β … | PLoS pathogens | Abhinaya Venkatesan Pablo D Jimenez Castro Arianna Morosetti Hannah Horvath Rebecca Chen | 2023/3/2 |
DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology | Genome biology | Christian B Macdonald David Nedrud Patrick Rockefeller Grimes Donovan Trinidad James S Fraser | 2023/2/24 |
Bacteriophages inhibit and evade cGAS-like immune function in bacteria | Cell | Erin Huiting Xueli Cao Jie Ren Januka S Athukoralage Zhaorong Luo | 2023/2/16 |
A counter-enzyme complex regulates glutamate metabolism in Bacillus subtilis | Nature chemical biology | Vijay Jayaraman D John Lee Nadav Elad Shay Vimer Michal Sharon | 2022/2 |
Of problems and opportunities—How to treat and how to not treat crystallographic fragment screening data | Protein Science | Manfred S Weiss Jan Wollenhaupt Galen J Correy James S Fraser Andreas Heine | 2022/9 |
Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance | Elife | Kaitlyn Tsai Vanja Stojković Lianet Noda-Garcia Iris D Young Alexander G Myasnikov | 2022/1/11 |
Ligand binding remodels protein side chain conformational heterogeneity | Elife | Stephanie A Wankowicz Saulo H de Oliveira Daniel W Hogan Henry van den Bedem James S Fraser | 2022/3/21 |
Fragment-Based Hit Discovery via Unsupervised Learning of Fragment-Protein Complexes | William McCorkindale Ivan Ahel Haim Barr Galen Correy James Fraser | 2022 | |
Integration of software tools for integrative modeling of biomolecular systems | Journal of Structural Biology | Matthew Hancock Thomas-Otavio Peulen Benjamin Webb Billy Poon James S Fraser | 2022/3/1 |
A language model beats alphafold2 on orphans | Nature Biotechnology | Jennifer M Michaud Ali Madani James S Fraser | 2022/11 |
Deep Insertion, Deletion, and Missense Mutation Libraries for Exploring Protein Variation in Evolution, Disease, and Biology | BioRxiv | Christian B Macdonald David Nedrud Patrick Rockefeller Grimes Donovan Trinidad James S Fraser | 2022/7/27 |
The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature | Science advances | Galen J Correy Daniel W Kneller Gwyndalyn Phillips Swati Pant Silvia Russi | 2022/5/27 |
Ensemble-function relationships to dissect mechanisms of enzyme catalysis | Science advances | Filip Yabukarski Tzanko Doukov Margaux M Pinney Justin T Biel James S Fraser | 2022/10/14 |
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics | Nature structural & molecular biology | Kaitlyn Tsai Vanja Stojković D John Lee Iris D Young Teresa Szal | 2022/2 |
Innate type 2 immunity controls hair follicle commensalism by Demodex mites | Immunity | Roberto R Ricardo-Gonzalez Maya E Kotas Claire E O’Leary Katelyn Singh William Damsky | 2022/10/11 |
qFit 3: Protein and ligand multiconformer modeling for X‐ray crystallographic and single‐particle cryo‐EM density maps | Protein Science | Blake T Riley Stephanie A Wankowicz Saulo HP de Oliveira Gydo CP van Zundert Daniel W Hogan | 2021/1 |
Co-Authors
