James L. Manley
Columbia University in the City of New York
H-index: 128
North America-United States
Top articles of James L. Manley
Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses
Cell Reports
2024/3/26
Characterization of the SF3B1–SUGP1 interface reveals how numerous cancer mutations cause mRNA missplicing
Genes & Development
2023/11/1
The E592K variant of SF3B1 creates unique RNA missplicing and associates with high-risk MDS without ring sideroblasts
Research Square
2023/4/14
A nucleolar long “non-coding” RNA encodes a novel protein that functions in response to stress
Proceedings of the National Academy of Sciences
2023/2/28
DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer
Proceedings of the National Academy of Sciences
2022/12/6
Beyond rRNA: nucleolar transcription generates a complex network of RNAs with multiple roles in maintaining cellular homeostasis
2022/8/1
Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS
Scientific Reports
2022/5/17
SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes
Proceedings of the National Academy of Sciences
2022/1/4
Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology
Genes & Development
2021/12/1
Oxidative stress induces Ser 2 dephosphorylation of the RNA polymerase II CTD and premature transcription termination
Transcription
2021/10/20
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation
Autophagy
2021/8/3
Transcription: mRNA polyadenylation in eukaryotes
2021/7/29
Multiple ways to a dead end: diverse mechanisms by which ALS mutant genes induce cell death
2021/4/3
Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains
Genome research
2020/12/1
Burkitt lymphoma-related TCF3 mutations alter TCF3 alternative splicing by disrupting hnRNPH1 binding
RNA biology
2020/10/2
Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
Nature communications
2020/6/23
ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs
Genes & Development
2020/6/1
Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation
Proceedings of the National Academy of Sciences
2020/5/12
Airway pressure release ventilation: A review of the evidence, theoretical benefits, and alternative titration strategies
2020/2
