James Hurley

James Hurley

University of California, Berkeley

H-index: 98

North America-United States

About James Hurley

James Hurley, With an exceptional h-index of 98 and a recent h-index of 55 (since 2020), a distinguished researcher at University of California, Berkeley, specializes in the field of membranes, structural biology, lysosomes, endosomes, autophagy.

His recent articles reflect a diverse array of research interests and contributions to the field:

Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites

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Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca2+-sensor ALG-2

A structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15

Structure and activation of the human autophagy-initiating ULK1C: PI3KC3-C1 supercomplex

Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore

A transient protein megacomplex that controls degradation of cell components

Longin domain GAP complexes in nutrient signalling, membrane traffic and neurodegeneration

James Hurley Information

University

Position

Professor of Molecular and Cell Biology

Citations(all)

44940

Citations(since 2020)

15816

Cited By

35601

hIndex(all)

98

hIndex(since 2020)

55

i10Index(all)

203

i10Index(since 2020)

167

Email

University Profile Page

Google Scholar

James Hurley Skills & Research Interests

membranes

structural biology

lysosomes

endosomes

autophagy

Top articles of James Hurley

Title

Journal

Author(s)

Publication Date

Kinetic investigation reveals an HIV-1 Nef-dependent increase in AP-2 recruitment and productivity at endocytic sites

Molecular Biology of the Cell

Yuichiro Iwamoto

Anna A Ye

Cyna Shirazinejad

James H Hurley

David G Drubin

2024/1/1

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Perspective

Sunkyung Kim

Jing Chen

Feiya Ou

Tian-Tian Liu

Suin Jo

...

2024/3/4

Mechanism and cellular function of direct membrane binding by the ESCRT and ERES-associated Ca2+-sensor ALG-2

Proceedings of the National Academy of Sciences

Sankalp Shukla

Wei Chen

Shanlin Rao

Serim Yang

Chenxi Ou

...

2024/2/27

A structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15

Biophysical Journal

Annan SI Cook

Minghao Chen

Xuefeng Ren

Shanlin Rao

Samantha N Garcia

...

2024/2/8

Structure and activation of the human autophagy-initiating ULK1C: PI3KC3-C1 supercomplex

Biophysical Journal

Minghao Chen

Xuefeng Ren

Annan SI Cook

James H Hurley

2024/2/8

Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore

Science Advances

Shanlin Rao

Marvin Skulsuppaisarn

Lisa M Strong

Xuefeng Ren

Michael Lazarou

...

2024/2/7

A transient protein megacomplex that controls degradation of cell components

Zhicheng Cui

James H Hurley

2023/1/25

Longin domain GAP complexes in nutrient signalling, membrane traffic and neurodegeneration

Rachel M Jansen

James H Hurley

2023/3

Structure of the lysosomal mTORC1–TFEB–Rag–Ragulator megacomplex

Nature

Zhicheng Cui

Gennaro Napolitano

Mariana EG de Araujo

Alessandra Esposito

Jlenia Monfregola

...

2023/2/16

A flat protein complex shapes rough ER membrane sheets

bioRxiv

Eric M Sawyer

Liv E Jensen

Janet B Meehl

Kevin P Larsen

Daniel A Petito

...

2023

Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes

bioRxiv

Kevin Rose

Tyler Jepson

Sankalp Shukla

Alex Maya-Romero

Martin Kampmann

...

2023/8/28

Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation

Science advances

Xuefeng Ren

Thanh N Nguyen

Wai Kit Lam

Cosmo Z Buffalo

Michael Lazarou

...

2023/2/15

Structural pathway for class III PI 3-kinase activation by the myristoylated GTP-binding pseudokinase VPS15

bioRxiv

Annan SI Cook

Minghao H Chen

Xuefeng Ren

Shanlin Rao

Samantha N Garcia

...

2023

Dynamics of upstream ESCRT organization at the HIV-1 budding site

Biophysical Journal

Arpa Hudait

James H Hurley

Gregory A Voth

2023/7/11

A RAB7A Phosphoswitch Coordinates Rubicon Homology Protein Regulation of PINK1/Parkin-Dependent Mitophagy

bioRxiv

Dan A Tudorica

Bishal LF Basak

Alexia Puerto Cordova

Grace Khuu

Kevin Rose

...

2023

Toward a standard model for autophagosome biogenesis

Journal of Cell Biology

Annan SI Cook

James H Hurley

2023/7/3

Mechanistic studies of endolysosomal membrane repair by the human ESCRT machinery through in vitro reconstitution

Biophysical Journal

Sankalp Shukla

Kevin P Larsen

Chenxi Ou

Kevin Rose

James H Hurley

2023/2/10

Amino acid sensing and lysosomal signaling complexes

Zhicheng Cui

Aaron MN Joiner

Rachel M Jansen

James H Hurley

2023/4/1

Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor EB

Biophysical Journal

Zhicheng Cui

James H Hurley

2023/2/10

Clathrin-associated AP-1 controls termination of STING signalling

Nature

Ying Liu

Pengbiao Xu

Sophie Rivara

Chong Liu

Jonathan Ricci

...

2022/10/27

See List of Professors in James Hurley University(University of California, Berkeley)

Co-Authors

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