James Fitzpatrick

James Fitzpatrick

Washington University in St. Louis

H-index: 38

North America-United States

About James Fitzpatrick

James Fitzpatrick, With an exceptional h-index of 38 and a recent h-index of 31 (since 2020), a distinguished researcher at Washington University in St. Louis, specializes in the field of Cell Biology / Neurobiology, Light / Electron / Ion Microscopy, Cryo-EM, Image Analysis, Scientific Technologies.

His recent articles reflect a diverse array of research interests and contributions to the field:

Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins

Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel

Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

Multiple genes core to ERAD, macro-autophagy and lysosomal degradation pathways participate in the proteostasis response in α1-antitrypsin deficiency

C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination.

Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism

Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain

Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice

James Fitzpatrick Information

University

Position

Professor

Citations(all)

9757

Citations(since 2020)

5531

Cited By

6022

hIndex(all)

38

hIndex(since 2020)

31

i10Index(all)

73

i10Index(since 2020)

64

Email

University Profile Page

Washington University in St. Louis

Google Scholar

View Google Scholar Profile

James Fitzpatrick Skills & Research Interests

Cell Biology / Neurobiology

Light / Electron / Ion Microscopy

Cryo-EM

Image Analysis

Scientific Technologies

Top articles of James Fitzpatrick

Title

Journal

Author(s)

Publication Date

Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins

Neuron

Michael R Strickland

Michael J Rau

Brock Summers

Katherine Basore

John Wulf

...

2024/1/13

Lipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel

Nature communications

Vikram Dalal

Mark J Arcario

John T Petroff

Brandon K Tan

Noah M Dietzen

...

2024/1/2

Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

Nature communications

Dhruva D Dhavale

Alexander M Barclay

Collin G Borcik

Katherine Basore

Deborah A Berthold

...

2024/3/29

Multiple genes core to ERAD, macro-autophagy and lysosomal degradation pathways participate in the proteostasis response in α1-antitrypsin deficiency

Cellular and Molecular Gastroenterology and Hepatology

Jie Li

Francesca Moretti

Tunda Hidvegi

Sanja Sviben

James AJ Fitzpatrick

...

2024/2/7

C-terminus induced asymmetry within a Rad52 homodecamer dictates single-position Rad51 nucleation in homologous recombination.

Biorxiv: the Preprint Server for Biology

Jaigeeth Deveryshetty

Rahul Chadda

Jenna Mattice

Simrithaa Karunakaran

Michael J Rau

...

2023/2/5

Deletion of taf1 and taf5 in zebrafish capitulate cardiac and craniofacial abnormalities associated with TAFopathies through perturbations in metabolism

Biology Open

Jamison Leid

Ryan Gray

Peter Rakita

Andrew L Koenig

Rohan Tripathy

...

2023/7/15

Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain

Nature communications

Shelei Pan

Peter H Yang

Dakota DeFreitas

Sruthi Ramagiri

Peter O Bayguinov

...

2023/1/27

Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2-dependent manner in mice

Science translational medicine

Samira Parhizkar

Grace Gent

Yun Chen

Nicholas Rensing

Maud Gratuze

...

2023/4/26

Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages

bioRxiv

Michael D Iglesia

Reyka G Jayasinghe

Siqi Chen

Nadezhda V Terekhanova

John M Herndon

...

2023/11/2

Endogenous recapitulation of Alzheimers disease neuropathology through human 3D direct neuronal reprogramming

bioRxiv

Zhao Sun

Ji-Sun Kwon

Yudong Ren

Shawei Chen

Kitra Cates

...

2023

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination

Cell reports

Jinchao Hou

Yingyue Zhou

Zhangying Cai

Marina Terekhova

Amanda Swain

...

2023/4/25

Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes

Nature Communications

Jaigeeth Deveryshetty

Rahul Chadda

Jenna R Mattice

Simrithaa Karunakaran

Michael J Rau

...

2023/10/5

Structural and functional analysis of human pannexin 2 channel

Nature communications

Zhihui He

Yonghui Zhao

Michael J Rau

James AJ Fitzpatrick

Rajan Sah

...

2023/3/27

Blocking the functional domain of TIP1 by antibodies sensitizes cancer to radiation therapy

Biomedicine & Pharmacotherapy

Abhay K Singh

David YA Dadey

Michael J Rau

James Fitzpatrick

Harendra K Shah

...

2023/10/1

Structures and gating of the Arabidopsis mechanosensitive ion channel MSL10

Biophysical Journal

Jingying Zhang

Tugba N Ozturk

Grigory Maksaev

Michael J Rau

James AJ Fitzpatrick

...

2023/2/10

Poly-basic peptides and polymers as new drug candidate against Plasmodium falciparum

bioRxiv

Roshan Sivakumar

Katherine Floyd

Erath Jessey

Jenny Kim Kim

Peter O Bayguinov

...

2023/9/16

Correction to: Size-Dependent Effective Diffusivity in Healthy Human and Porcine Joint Synovium

Annals of biomedical engineering

Guang Young

Alexandra L Davis

Thomas M McGrath

Pham Christine TN

Fitzpatrick James AJ

...

2022/4/1

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

Communications Biology

Cliff J Luke

Stephanie Markovina

Misty Good

Ira E Wight

Brian J Thomas

...

2022/1/12

Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors

Nature communications

Ankan K Bhadra

Michael J Rau

Jil A Daw

James AJ Fitzpatrick

Conrad C Weihl

...

2022/8/5

Epithelial abnormalities in the small intestine of Zambian children with stunting

Frontiers in Medicine

Chola Mulenga

Sanja Sviben

Kanta Chandwe

Beatrice Amadi

Violet Kayamba

...

2022/3/16

See List of Professors in James Fitzpatrick University(Washington University in St. Louis)