James Ellis

James Ellis

University of Toronto

H-index: 50

North America-Canada

About James Ellis

James Ellis, With an exceptional h-index of 50 and a recent h-index of 31 (since 2020), a distinguished researcher at University of Toronto,

His recent articles reflect a diverse array of research interests and contributions to the field:

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction

Calcium-Dependent Hyperexcitability in Human Stem Cell–Derived Rett Syndrome Neuronal Networks

Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation

Systematic characterization of regulatory variants of blood pressure genes

Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis

Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models

Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

James Ellis Information

University

Position

The Hospital for Sick Children

Citations(all)

10329

Citations(since 2020)

3210

Cited By

8430

hIndex(all)

50

hIndex(since 2020)

31

i10Index(all)

92

i10Index(since 2020)

60

Email

University Profile Page

Google Scholar

Top articles of James Ellis

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Molecular and Cellular Neuroscience

2024/4/23

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction

bioRxiv

2023

Calcium-Dependent Hyperexcitability in Human Stem Cell–Derived Rett Syndrome Neuronal Networks

Biological Psychiatry Global Open Science

2024/3/1

Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation

Stem Cell Research

2023/6/1

Systematic characterization of regulatory variants of blood pressure genes

Cell Genomics

2023/7/12

Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis

Development

2023/7/1

Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models

Nature Communications

2023/4/5

Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

bioRxiv

2023/3/1

Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons

BMC Medical Genomics

2023/1/12

Hyperexcitability in human MECP2 null neuronal networks manifests as calcium-dependent reverberating super bursts

bioRxiv

2023

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies

Cell Reports

2022/11/22

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

Translational psychiatry

2022/10/18

Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components

bioRxiv

2022/10/13

Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells

2022/6/9

Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy

NPJ genomic medicine

2022/3/14

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

The Journal of Clinical Investigation

2022/3/1

Multielectrode arrays for functional phenotyping of neurons from induced pluripotent stem cell models of neurodevelopmental disorders

2022/2/16

Identification of TIA1 mRNA targets during human neuronal development

Molecular Biology Reports

2021/9

Wei Wei
Wei Wei

H-Index: 5

James Ellis
James Ellis

H-Index: 28

Quantification of mRNA ribosomal engagement in human neurons using parallel translating ribosome affinity purification (TRAP) and RNA sequencing

STAR protocols

2021/3/19

Alternative polyadenylation is a determinant of oncogenic Ras function

Science Advances

2021/12/17

See List of Professors in James Ellis University(University of Toronto)