James Ellis

James Ellis

University of Toronto

H-index: 50

North America-Canada

About James Ellis

James Ellis, With an exceptional h-index of 50 and a recent h-index of 31 (since 2020), a distinguished researcher at University of Toronto,

His recent articles reflect a diverse array of research interests and contributions to the field:

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction

Calcium-Dependent Hyperexcitability in Human Stem Cell–Derived Rett Syndrome Neuronal Networks

Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation

Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis

Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models

Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons

James Ellis Information

University

Position

The Hospital for Sick Children

Citations(all)

10329

Citations(since 2020)

3210

Cited By

8430

hIndex(all)

50

hIndex(since 2020)

31

i10Index(all)

92

i10Index(since 2020)

60

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Top articles of James Ellis

Title

Journal

Author(s)

Publication Date

iPSC-derived healthy human astrocytes selectively load miRNAs targeting neuronal genes into extracellular vesicles

Molecular and Cellular Neuroscience

Sara Gordillo-Sampedro

Lina Antounians

Wei Wei

Marat Mufteev

Bas Lendemeijer

...

2024/4/23

Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction

bioRxiv

Caroline Kinnear

Abdelrahman Said

Guoliang Meng

Yimu Zhao

Erika Y Wang

...

2023

Calcium-Dependent Hyperexcitability in Human Stem Cell–Derived Rett Syndrome Neuronal Networks

Biological Psychiatry Global Open Science

Kartik S Pradeepan

Fraser P McCready

Wei Wei

Milad Khaki

Wenbo Zhang

...

2024/3/1

Generation and characterization of a human iPSC line and gene-corrected isogenic line derived from a patient with a CELF2 gene mutation

Stem Cell Research

Takao Ukaji

Mikako Takahashi-Shibata

Daisuke Arai

Harumi Tsutsumi

Shori Tajima

...

2023/6/1

Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis

Development

Biren M Dave

Xin Chen

Fraser McCready

Connor S Charton

Rachel M Morley

...

2023/7/1

Buffering of transcription rate by mRNA half-life is a conserved feature of Rett syndrome models

Nature Communications

Deivid C Rodrigues

Marat Mufteev

Kyoko E Yuki

Ashrut Narula

Wei Wei

...

2023/4/5

Transcriptional buffering and 3ʹUTR lengthening are shaped during human neurodevelopment by shifts in mRNA stability and microRNA load

bioRxiv

Marat Mufteev

Deivid C Rodrigues

Kyoko E Yuki

Ashrut Narula

Wei Wei

...

2023/3/1

Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons

BMC Medical Genomics

M Faheem

E Deneault

R Alexandrova

DC Rodrigues

G Pellecchia

...

2023/1/12

Hyperexcitability in human MECP2 null neuronal networks manifests as calcium-dependent reverberating super bursts

bioRxiv

Kartik S Pradeepan

Fraser P McCready

Wei Wei

Milad Khaki

Wenbo Zhang

...

2023

Systematic characterization of regulatory variants of blood pressure genes

Cell Genomics

Winona Oliveros

Kate Delfosse

Daniella F Lato

Katerina Kiriakopulos

Milad Mokhtaridoost

...

2023/7/12

JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency

The Journal of Clinical Investigation

Jui M Dave

Raja Chakraborty

Aglaia Ntokou

Junichi Saito

Fatima Z Saddouk

...

2022/3/1

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies

Cell Reports

Nadeem Murtaza

Annie A Cheng

Chad O Brown

Durga Praveen Meka

Shuai Hong

...

2022/11/22

Multielectrode arrays for functional phenotyping of neurons from induced pluripotent stem cell models of neurodevelopmental disorders

Fraser P McCready

Sara Gordillo-Sampedro

Kartik Pradeepan

Julio Martinez-Trujillo

James Ellis

2022/2/16

Wide spectrum of neuronal and network phenotypes in human stem cell-derived excitatory neurons with Rett syndrome-associated MECP2 mutations

Translational psychiatry

Rebecca SF Mok

Wenbo Zhang

Taimoor I Sheikh

Kartik Pradeepan

Isabella R Fernandes

...

2022/10/18

Advanced physiological maturation of iPSC-derived human cardiomyocytes using an algorithm-directed optimization of defined media components

bioRxiv

Neal I Callaghan

Lauren J Durland

Wenliang Chen

Uros Kuzmanov

Maria Zena Miranda

...

2022/10/13

Targeting NMDA receptors in neuropsychiatric disorders by drug screening on human neurons derived from pluripotent stem cells

Wenbo Zhang

P Joel Ross

James Ellis

Michael W Salter

2022/6/9

Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy

NPJ genomic medicine

Robert Lesurf

Abdelrahman Said

Oyediran Akinrinade

Jeroen Breckpot

Kathleen Delfosse

...

2022/3/14

Alternative polyadenylation is a determinant of oncogenic Ras function

Science Advances

Aishwarya Subramanian

Mathew Hall

Huayun Hou

Marat Mufteev

Bin Yu

...

2021/12/17

Identification of TIA1 mRNA targets during human neuronal development

Molecular Biology Reports

Loryn P Byres

Marat Mufteev

Kyoko E Yuki

Wei Wei

Alina Piekna

...

2021/9

Quantification of mRNA ribosomal engagement in human neurons using parallel translating ribosome affinity purification (TRAP) and RNA sequencing

STAR protocols

Deivid Carvalho Rodrigues

Marat Mufteev

James Ellis

2021/3/19

See List of Professors in James Ellis University(University of Toronto)