Jack Taunton

Jack Taunton

University of California, San Francisco

H-index: 65

North America-United States

About Jack Taunton

Jack Taunton, With an exceptional h-index of 65 and a recent h-index of 43 (since 2020), a distinguished researcher at University of California, San Francisco, specializes in the field of chemical biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center

An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes

Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes

Signal peptide mimicry primes Sec61 for client-selective inhibition

Large library docking for novel SARS‐CoV‐2 main protease non‐covalent and covalent inhibitors

mRNA decoding in human is kinetically and structurally distinct from bacteria

An E3 ligase network engages GCN1 to promote elongation factor-1α degradation on stalled ribosomes

IFITM proteins assist cellular uptake of diverse linked chemotypes

Jack Taunton Information

University

Position

___

Citations(all)

22438

Citations(since 2020)

11267

Cited By

15550

hIndex(all)

65

hIndex(since 2020)

43

i10Index(all)

100

i10Index(since 2020)

89

Email

University Profile Page

University of California, San Francisco

Google Scholar

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Jack Taunton Skills & Research Interests

chemical biology

Top articles of Jack Taunton

Title

Journal

Author(s)

Publication Date

The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center

Nature Chemical Biology

João PL Coelho

Matthew CJ Yip

Keely Oltion

Jack Taunton

Sichen Shao

2024/1/3

An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes

Cell

Keely Oltion

Jordan D Carelli

Tangpo Yang

Stephanie K See

Hao-Yuan Wang

...

2023/1/19

Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes

Nature Chemistry

Ying Chen

Gregory B Craven

Roarke A Kamber

Adolfo Cuesta

Serhii Zhersh

...

2023/11

Signal peptide mimicry primes Sec61 for client-selective inhibition

Nature Chemical Biology

Shahid Rehan

Dale Tranter

Phillip P Sharp

Gregory B Craven

Eric Lowe

...

2023/9

Large library docking for novel SARS‐CoV‐2 main protease non‐covalent and covalent inhibitors

Protein Science

Elissa A Fink

Conner Bardine

Stefan Gahbauer

Isha Singh

Tyler C Detomasi

...

2023/8

mRNA decoding in human is kinetically and structurally distinct from bacteria

Nature

Mikael Holm

S Kundhavai Natchiar

Emily J Rundlet

Alexander G Myasnikov

Zoe L Watson

...

2023/5/4

An E3 ligase network engages GCN1 to promote elongation factor-1α degradation on stalled ribosomes

bioRxiv

Keely Oltion

Jordan D Carelli

Tangpo Yang

Stephanie K See

Hao-Yuan Wang

...

2022/3/22

IFITM proteins assist cellular uptake of diverse linked chemotypes

Science

Kevin Lou

Douglas R Wassarman

Tangpo Yang

YiTing Paung

Ziyang Zhang

...

2022/12/9

Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3

Nature chemistry

Hao-Yuan Wang

Haojun Yang

Mikael Holm

Harrison Tom

Keely Oltion

...

2022/12

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

Nature chemical biology

Tangpo Yang

Adolfo Cuesta

Xiaobo Wan

Gregory B Craven

Brad Hirakawa

...

2022/9

Inhibition of the Sec61 translocon overcomes cytokine‐induced glucocorticoid resistance in T‐cell acute lymphoblastic leukaemia

British Journal of Haematology

Lauren K Meyer

Cristina Delgado‐Martin

Phillip P Sharp

Benjamin J Huang

Dustin McMinn

...

2022/7

Identifying the cellular target of cordyheptapeptide A and synthetic derivatives

ACS chemical biology

Victoria G Klein

Walter M Bray

Hao-Yuan Wang

Quinn Edmondson

Joshua Schwochert

...

2021/7/12

p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway (vol 7, 542485, 2020)

Frontiers in cardiovascular medicine

Rei J Abe

Hannah Savage

Masaki Imanishi

Priyanka Banerjee

Sivareddy Kotla

...

2020/11/13

Corrigendum: p90RSK-MAGI1 module controls endothelial permeability by post-translational modifications of magi1 and hippo pathway

Frontiers in Cardiovascular Medicine

Rei J Abe

Hannah Savage

Masaki Imanishi

Priyanka Banerjee

Sivareddy Kotla

...

2021/2/19

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma

Blood advances

Poornima Ramkumar

Anthony B Abarientos

Ruilin Tian

Meghan Seyler

Jaime T Leong

...

2020/7/14

Discovery of lysine-targeted eIF4E inhibitors through covalent docking

Journal of the American Chemical Society

Xiaobo Wan

Tangpo Yang

Adolfo Cuesta

Xiaming Pang

Trent E Balius

...

2020/2/27

Ligand conformational bias drives enantioselective modification of a surface-exposed lysine on Hsp90

Journal of the American Chemical Society

Adolfo Cuesta

Xiaobo Wan

Alma L Burlingame

Jack Taunton

2020/2/3

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

Nature

David E Gordon

Gwendolyn M Jang

Mehdi Bouhaddou

Jiewei Xu

Kirsten Obernier

...

2020/7/16

See List of Professors in Jack Taunton University(University of California, San Francisco)