Isaac Klein

Isaac Klein

Harvard University

H-index: 22

North America-United States

About Isaac Klein

Isaac Klein, With an exceptional h-index of 22 and a recent h-index of 20 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Cancer Biology, Oncology, Condensate Biology, Drug Discovery, Gene Regulation.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract LB199: Condensate modulator sequesters beta-catenin into depot condensates and demonstrates competitive anti-tumor activity in animal models ofcolorectal cancer

Viral condensates and methods of use thereof

CD-CODE: crowdsourcing condensate database and encyclopedia

Biomolecular condensates as novel antiviral targets

Methods and assays for modulating gene transcription by modulating condensates

The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17

Methods of characterizing and utilizing agent-condensate interactions

Principles and functions of condensate modifying drugs

Isaac Klein Information

University

Position

The Dana-Farber Cancer Institute and The Whitehead Institute MIT

Citations(all)

6635

Citations(since 2020)

4866

Cited By

3412

hIndex(all)

22

hIndex(since 2020)

20

i10Index(all)

25

i10Index(since 2020)

24

Email

University Profile Page

Harvard University

Google Scholar

View Google Scholar Profile

Isaac Klein Skills & Research Interests

Cancer Biology

Oncology

Condensate Biology

Drug Discovery

Gene Regulation

Top articles of Isaac Klein

Title

Journal

Author(s)

Publication Date

Abstract LB199: Condensate modulator sequesters beta-catenin into depot condensates and demonstrates competitive anti-tumor activity in animal models ofcolorectal cancer

Cancer Research

Costa Salojin

Douglas Baumann

Adam Talbot

Kip West

Thomas Durand-Reville

...

2024/4/5

Viral condensates and methods of use thereof

2023/7/27

CD-CODE: crowdsourcing condensate database and encyclopedia

Nature Methods

Nadia Rostam

Soumyadeep Ghosh

Chi Fung Willis Chow

Anna Hadarovich

Cedric Landerer

...

2023/5

Biomolecular condensates as novel antiviral targets

Erik W Martin

Christiane Iserman

Balaji Olety

Diana M Mitrea

Isaac A Klein

2023/12/5

Methods and assays for modulating gene transcription by modulating condensates

2022/4/21

The transcription factor PAX8 promotes angiogenesis in ovarian cancer through interaction with SOX17

Science signaling

Daniele Chaves-Moreira

Marilyn A Mitchell

Cristina Arruza

Priyanka Rawat

Simone Sidoli

...

2022/4/5

Methods of characterizing and utilizing agent-condensate interactions

2022/12/8

Principles and functions of condensate modifying drugs

Avinash Patel

Diana Mitrea

Vigneshwaran Namasivayam

Mark A Murcko

Michael Wagner

...

2022/11/22

Modulating biomolecular condensates: a novel approach to drug discovery

Diana M Mitrea

Matthäus Mittasch

Beatriz Ferreira Gomes

Isaac A Klein

Mark A Murcko

2022/11

Engineering bioactive dimeric transcription factor analogs via palladium rebound reagents

Journal of the American Chemical Society

Muhammad Jbara

Sebastian Pomplun

Carly K Schissel

Susana Wilson Hawken

Ann Boija

...

2021/7/22

Partitioning of cancer therapeutics in nuclear condensates.

Science

Isaac A Klein

Ann Boija

Lena K Afeyan

Susana Wilson Hawken

Mengyang Fan

...

2020/6/19

Impact of COVID-19 on patients with Cancer receiving Immune Checkpoint inhibitors

Journal of Immunotherapy and Precision Oncology

Ai-Tram N Bui

Kevin Tyan

Anita Giobbie-Hurder

Isaac A Klein

Michael P Manos

...

2021/5/1

Predicting master transcription factors from pan-cancer expression data

Science advances

Jessica Reddy

Marcos AS Fonseca

Rosario I Corona

Robbin Nameki

Felipe Segato Dezem

...

2021/11/24

Parallel automated flow synthesis of covalent protein complexes that can inhibit MYC-driven transcription

ACS Central Science

Sebastian Pomplun

Muhammad Jbara

Carly K Schissel

Susana Wilson Hawken

Ann Boija

...

2021/8/4

Abstract GS3-10: Partitioning of cancer therapeutics in nuclear condensates

Cancer Research

Isaac Klein

Ann Boija

Lena Afeyan

Susana Wilson Hawken

Mengyang Fan

...

2021/2/15

Biomolecular condensates and cancer

Ann Boija

Isaac A Klein

Richard A Young

2021/2/8

Impact of cancer history on outcomes among hospitalized patients with COVID-19

The oncologist

Isaac A Klein

Shoshana M Rosenberg

Kerry L Reynolds

Leyre Zubiri

Rachel Rosovsky

...

2021/8/1

481 Impact of COVID-19 on cancer patients receiving immune checkpoint inhibitors

Kevin Tyan

Ai-Tram Bui

Anita Giobbie-Hurder

Isaac Klein

Michael Manos

...

2020/11/1

lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation

Nature cell biology

Kaveh Daneshvar

M Behfar Ardehali

Isaac A Klein

Fu-Kai Hsieh

Arcadia J Kratkiewicz

...

2020/10

Abstract PO-063: Impact of cancer history on outcomes among hospitalized COVID-19 patients: A case-control analysis

Clinical Cancer Research

Isaac Klein

Shoshana Rosenberg

Camille Kotton

Kerry Reynolds

Leyre Zubiri

...

2020/9/15

See List of Professors in Isaac Klein University(Harvard University)

Co-Authors

H-index: 189
Richard Young

Richard Young

Massachusetts Institute of Technology

H-index: 48
Davide F. Robbiani, MD, PhD

Davide F. Robbiani, MD, PhD

Università della Svizzera Italiana

H-index: 22
Alessandra Dall'Agnese

Alessandra Dall'Agnese

Massachusetts Institute of Technology

H-index: 19
Jurian Schuijers

Jurian Schuijers

Universiteit Utrecht

H-index: 18
Benjamin R. Sabari

Benjamin R. Sabari

University of Texas Southwestern Medical Center

H-index: 17
Daniel Day

Daniel Day

Massachusetts Institute of Technology

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