Ignaty Leshchiner

Ignaty Leshchiner

Harvard University

H-index: 39

North America-United States

About Ignaty Leshchiner

Ignaty Leshchiner, With an exceptional h-index of 39 and a recent h-index of 37 (since 2020), a distinguished researcher at Harvard University,

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract LB449: Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

Methylation based phylogeny and timing in cancer

Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

Longitudinal whole exome sequencing of cell-free DNA in advanced bladder cancer.

Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors

Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer

Drug persistence pathways in ovarian cancer identified by single-cell analysis of patient samples and cell line models

Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer

Ignaty Leshchiner Information

University

Position

Broad Institute of Harvard and MIT

Citations(all)

15199

Citations(since 2020)

12612

Cited By

7243

hIndex(all)

39

hIndex(since 2020)

37

i10Index(all)

65

i10Index(since 2020)

59

Email

University Profile Page

Harvard University

Google Scholar

View Google Scholar Profile

Top articles of Ignaty Leshchiner

Title

Journal

Author(s)

Publication Date

Abstract LB449: Strategies to overcome resistance to PI3Kalpha-selective inhibitors mediated by acquired alterations in the PI3K/AKT pathway

Cancer Research

Ferran Fece de la Cruz

Andreas Varkaris

Elizabeth E Martin

Bryanna L Norden

Nicholas Chevalier

...

2024/4/5

Methylation based phylogeny and timing in cancer

Cancer Research

Nataliya Guteneva

Eliezer Lichter

Ignaty Leshchiner

2024/3/22

Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations

Cancer Discovery

Andreas Varkaris

Ferran Fece de la Cruz

Elizabeth E Martin

Bryanna L Norden

Nicholas Chevalier

...

2024/2/8

Longitudinal whole exome sequencing of cell-free DNA in advanced bladder cancer.

Arvind Ravi

Ilana Epstein

Dory Freeman

Praful Ravi

Tim Coorens

...

2024/2/1

Understanding Resistance Mechanisms and Growth Kinetics of CLL Treated with Covalent and Non-Covalent BTK Inhibitors

Blood

Aishath Naeem

Liang Li

Filippo Utro

Justin Cha

Junko Tsuji

...

2023/11/28

Immunoproteasome expression and checkpoint blockade response in advanced non-small cell lung cancer

Cancer Research

Vivek Naranbhai

Arvind Ravi

Matthew Hellmann

Monica Arniella

Mark Holton

...

2023/4/4

Drug persistence pathways in ovarian cancer identified by single-cell analysis of patient samples and cell line models

Cancer Research

Elizaveta Leshchiner

Richard Panayiotou

Anay Gupta

Thomas Zhang

Kayli Neil

...

2023/4/4

Germline mutations and developmental mosaicism underlying EGFR-mutant lung cancer

medRxiv

Risa Burr

Ignaty Leshchiner

Christina L Costantino

Martin Blohmer

Tilak Sundaresan

...

2023/9/29

Author Correction: The evolutionary history of 2,658 cancers (Nature,(2020), 578, 7793,(122-128), 10.1038/s41586-019-1907-7)

Nature

Moritz Gerstung

Clemency Jolly

Ignaty Leshchiner

Stefan C Dentro

Santiago Gonzalez

...

2023/2/16

Link to this full text: http://hdl. handle. net

ONCOLOGY

Riccardo Autorino

Pierluigi Bove

Marco De Sio

Roberto Miano

Salvatore Micali

...

2023/1/9

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Blood Advances

Aishath Naeem

Filippo Utro

Qing Wang

Justin Cha

Mauno Vihinen

...

2023/5/9

Abstract A013: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma

Cancer Research

David A Braun

Derin B Keskin

Sachet A Shukla

Bradley A McGregor

Nicholas R Schindler

...

2023/8/15

Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Nature genetics

Isidro Cortés-Ciriano

Jake June-Koo Lee

Ruibin Xi

Dhawal Jain

Youngsook L Jung

...

2023/6

Inferring early genetic progression in cancers with unobtainable premalignant disease

Nature Cancer

Ignaty Leshchiner

Edmund A Mroz

Justin Cha

Daniel Rosebrock

Oliver Spiro

...

2023/4

Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Nature genetics

Arvind Ravi

Matthew D Hellmann

Monica B Arniella

Mark Holton

Samuel S Freeman

...

2023/5

Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome

Nature Medicine

Erin M Parry

Ignaty Leshchiner

Romain Guièze

Connor Johnson

Eugen Tausch

...

2023/1/9

Mechanisms of genetic predisposition to multifocal lung cancer

Cancer Research

Risa Burr

Ignaty Leshchiner

Christina L Costantino

Martin Blohmer

Tilak Sundaresan

...

2023/4/4

Abstract PR015: Tumor-specific immunity generated by a personalized neoantigen vaccination incorporating locally delivered ipilimumab in renal cell carcinoma

Cancer Research

David A Braun

Derin B Keskin

Sachet A Shukla

Bradley A McGregor

Nicholas R Schindler

...

2023/8/15

ESR1 mutational landscape and impact of co-existing resistance variants on clinical outcomes in patients with metastatic breast cancer.

Arielle J Medford

Ignaty Leshchiner

Justin Cha

Lesli Ann Kiedrowski

Andrzej Niemierko

...

2023/6/1

Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples

Blood

Jasneet Kaur Khalsa

Justin Cha

Filippo Utro

Aishath Naeem

Ishwarya Murali

...

2023/8/3

See List of Professors in Ignaty Leshchiner University(Harvard University)

Co-Authors

H-index: 228
Gad Getz

Gad Getz

Harvard University

H-index: 89
Shamil Sunyaev

Shamil Sunyaev

Harvard University

academic-engine