Hynek Wichterle

Hynek Wichterle

Columbia University in the City of New York

H-index: 47

North America-United States

About Hynek Wichterle

Hynek Wichterle, With an exceptional h-index of 47 and a recent h-index of 36 (since 2020), a distinguished researcher at Columbia University in the City of New York, specializes in the field of transcription factors, enhancers, ALS, motor neurons, neuronal maturation.

His recent articles reflect a diverse array of research interests and contributions to the field:

Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons

Major β cell-specific functions of NKX2. 2 are mediated via the NK2-specific domain

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective

A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective

Long 3′ UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation

Species-specific progenitor sub-domain extends neurogenesis and increases human motor neuron production

Human-specific progenitor sub-domain contributes to extended neurogenesis and increased motor neuron production

Ranking reprogramming factors for cell differentiation

Hynek Wichterle Information

University

Position

___

Citations(all)

17713

Citations(since 2020)

4303

Cited By

15121

hIndex(all)

47

hIndex(since 2020)

36

i10Index(all)

69

i10Index(since 2020)

59

Email

University Profile Page

Columbia University in the City of New York

Google Scholar

View Google Scholar Profile

Hynek Wichterle Skills & Research Interests

transcription factors

enhancers

ALS

motor neurons

neuronal maturation

Top articles of Hynek Wichterle

Title

Journal

Author(s)

Publication Date

Embryonic motor neuron programming factors reactivate immature gene expression and suppress ALS pathologies in postnatal motor neurons

bioRxiv

Emily R Lowry

Tulsi Patel

Jonathon A Costa

Elizabeth Chang

Shahroz Tariq

...

2024

Major β cell-specific functions of NKX2. 2 are mediated via the NK2-specific domain

Genes & Development

Vladimir Abarinov

Joshua A Levine

Angela J Churchill

Bryce Hopwood

Cailin S Deiter

...

2023/6/1

Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective

ACS Chemical Neuroscience

Han Wee Ong

Yi Liang

William Richardson

Emily R Lowry

Carrow I Wells

...

2023/4/21

A Potent and Selective CDKL5/GSK3 Chemical Probe is Neuroprotective

bioRxiv

Han Wee Ong

Yi Liang

William Richardson

Emily R Lowry

Carrow I Wells

...

2023/2/10

Long 3′ UTRs predispose neurons to inflammation by promoting immunostimulatory double-stranded RNA formation

Science Immunology

Tyler J Dorrity

Heegwon Shin

Kenenni A Wiegand

Justin Aruda

Michael Closser

...

2023/10/20

Species-specific progenitor sub-domain extends neurogenesis and increases human motor neuron production

Hynek Wichterle

Sumin Jang

Elias Gunmit

2023/6/22

Human-specific progenitor sub-domain contributes to extended neurogenesis and increased motor neuron production

bioRxiv

Sumin Jang

Elias Gunmit

Hynek Wichterle

2022/7/5

Ranking reprogramming factors for cell differentiation

Nature methods

Jennifer Hammelman

Tulsi Patel

Michael Closser

Hynek Wichterle

David Gifford

2022/7

An expansion of the non-coding genome and its regulatory potential underlies vertebrate neuronal diversity

Neuron

Michael Closser

Yuchun Guo

Ping Wang

Tulsi Patel

Sumin Jang

...

2022/1/5

Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

bioRxiv

Delfina Larrea

Kirstin A Tamucci

Khushbu Kabra

Kevin Velasco

Taekyung D Yun

...

2022

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Nature communications

Tulsi Patel

Jennifer Hammelman

Siaresh Aziz

Sumin Jang

Michael Closser

...

2022/9/15

General and cell-type-specific aspects of the motor neuron maturation transcriptional program

BioRxiv

Tulsi Patel

Jennifer Hammelman

Michael Closser

David K Gifford

Hynek Wichterle

2021/3/6

Compounds, compositions, and methods for suppressing toxic endoplasmic reticulum stress

2021/2/11

A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus

Developmental cell

Boaz E Aronson

Laurianne Scourzic

Veevek Shah

Emily Swanzey

Andreas Kloetgen

...

2021/11/22

Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification

Development

Vincent Mouilleau

Célia Vaslin

Rémi Robert

Simona Gribaudo

Nour Nicolas

...

2021/3/15

Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells

Neuroscience

Alejandro Garcia-Diaz

Gizem Efe

Khushbu Kabra

Achchhe Patel

Emily R Lowry

...

2020/12/1

Differential abilities to engage inaccessible chromatin diversify vertebrate Hox binding patterns

Development

Milica Bulajić

Divyanshi Srivastava

Jeremy S Dasen

Hynek Wichterle

Shaun Mahony

...

2020/11/15

See List of Professors in Hynek Wichterle University(Columbia University in the City of New York)