Husain Yar Khan

Husain Yar Khan

Wayne State University

H-index: 19

North America-United States

About Husain Yar Khan

Husain Yar Khan, With an exceptional h-index of 19 and a recent h-index of 18 (since 2020), a distinguished researcher at Wayne State University, specializes in the field of Translational Cancer Research, Cancer Chemoprevention, Pancreatic Cancer.

His recent articles reflect a diverse array of research interests and contributions to the field:

Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma

Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma

Nuclear export inhibitor cooperates with PARP inhibitor to suppress the growth of metastatic castration resistant prostate cancer in vivo

Next generation nuclear export blocker KPT8602 synergizes with KRASG12D inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal …

Abstract B077: KRASG12D inhibitor MRTX1133 synergizes with the next generation nuclear transport protein inhibitor eltanexor resulting in enhanced antitumor …

Emerging talents in pharmacology of anti-cancer drugs 2022

Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis

Abstract LB299: Identification of key regulators for nuclear protein export inhibitor and chemotherapy combination in pancreatic cancer using spatial genomics approach

Husain Yar Khan Information

University

Position

Karmanos Cancer Institute School of Medicine

Citations(all)

1535

Citations(since 2020)

835

Cited By

996

hIndex(all)

19

hIndex(since 2020)

18

i10Index(all)

32

i10Index(since 2020)

24

Email

University Profile Page

Wayne State University

Google Scholar

View Google Scholar Profile

Husain Yar Khan Skills & Research Interests

Translational Cancer Research

Cancer Chemoprevention

Pancreatic Cancer

Top articles of Husain Yar Khan

Title

Journal

Author(s)

Publication Date

Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma

Cancer Research

Mandana Kamgar

Husain Yar Khan

Amro Aboukameel

Sahar F Bannoura

Brian Y Chung

...

2024/4/5

Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma

Cancer Research

Sahar F Bannoura

Husain Y Khan

Amro Aboukameel

Md Hafiz Uddin

Rund Nimri

...

2024/3/22

Nuclear export inhibitor cooperates with PARP inhibitor to suppress the growth of metastatic castration resistant prostate cancer in vivo

Cancer Research

Md Hafiz Uddin

Amro Aboukameel

Husain Y Khan

Sahar F Bannoura

Frank Cackowski

...

2024/3/22

Next generation nuclear export blocker KPT8602 synergizes with KRASG12D inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal …

Cancer Research

Husain Yar Khan

Amro Aboukameel

Md Hafiz Uddin

Sahar F Bannoura

Khaled Keffri

...

2024/3/22

Abstract B077: KRASG12D inhibitor MRTX1133 synergizes with the next generation nuclear transport protein inhibitor eltanexor resulting in enhanced antitumor …

Cancer Research

Husain Y Khan

Amro Aboukameel

Md Hafiz Uddin

Mohammad Najeeb Al-Hallak

Eliza W Beal

...

2024/1/16

Emerging talents in pharmacology of anti-cancer drugs 2022

Frontiers in Pharmacology

Husain Yar Khan

Khuloud Bajbouj

Mai F Tolba

2023/4/19

Regulator of Chromosome Condensation (RCC1) a novel therapeutic target in pancreatic ductal adenocarcinoma drives tumor progression via the c-Myc-RCC1-Ran axis

bioRxiv

Sahar F Bannoura

Amro Aboukameel

Husain Yar Khan

Md Hafiz Uddin

Hyejeong Jang

...

2023/12/18

Abstract LB299: Identification of key regulators for nuclear protein export inhibitor and chemotherapy combination in pancreatic cancer using spatial genomics approach

Cancer Research

Md Hafiz Uddin

Sahar F Bannoura

Husain Y Khan

Amro Aboukameel

Yiwei Li

...

2023/4/14

Molecular analysis of XPO1 inhibitor and gemcitabine–nab‐paclitaxel combination in KPC pancreatic cancer mouse model

Clinical and Translational Medicine

Md Hafiz Uddin

Mohammad Najeeb Al‐Hallak

Husain Yar Khan

Amro Aboukameel

Yiwei Li

...

2023/12

A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic adenocarcinoma.

Mandana Kamgar

Husain Yar Khan

Amro Aboukameel

Sahar Bannoura

Brian Y Chung

...

2023/2/1

Anticancer Efficacy of KRASG12C Inhibitors Is Potentiated by PAK4 Inhibitor KPT9274 in Preclinical Models of KRASG12C-Mutant Pancreatic and Lung Cancers

Molecular Cancer Therapeutics

Husain Yar Khan

Misako Nagasaka

Amro Aboukameel

Osama Alkhalili

Md Hafiz Uddin

...

2023/12/1

Targeting cellular metabolism with CPI-613 sensitizes pancreatic cancer cells to radiation therapy

Advances in Radiation Oncology

Husain Yar Khan

Mandana Kamgar

Amro Aboukameel

Sahar Bannoura

Brian Y Chung

...

2023/1/1

The clinical menin inhibitor ziftomenib and the nuclear export inhibitor selinexor synergistically inhibit the growth of MLL-r AML

Blood

Md Hafiz Uddin

Amro Aboukameel

Husain Khan

Sahar Bannoura

Abhinav Deol

...

2023/11/2

P-76 Genomic and transcriptomic characterization of pancreatic neuroendocrine tumors reveals novel therapeutic candidates

Annals of Oncology

A Azmi

Z Mahdi

S Bannoura

M Al-Hallak

M Uddin

...

2023/6/1

Association of PAK4 expression with overall survival in patients with non-small cell lung cancer (NSCLC).

Hirva Mamdani

Sharon Wu

Erin Morgan

Husain Yar Khan

Chadi Nabhan

...

2022/6/1

Novel Combination of Clinical Menin Inhibitor Ziftomenib and the Nuclear Export Inhibitor Selinexor Synergistically Inhibit MLL-r AML

Blood

Md Hafiz Uddin

Amro Aboukameel

Husain Khan

Sahar Bannoura

Yiwei Li

...

2022/11/15

Inhibitor of the nuclear transport protein XPO1 enhances the anticancer efficacy of KRAS G12C inhibitors in preclinical models of KRAS G12C–mutant cancers

Cancer research communications

Husain Yar Khan

Misako Nagasaka

Yiwei Li

Amro Aboukameel

Md Hafiz Uddin

...

2022/5/10

Anti-tumor activity of KRASG12C inhibitors is enhanced when combined with Cdc42 effector p21-activated kinase 4 targeting agents

Cancer Research

Husain Yar Khan

Sahar Bannoura

Hirva Mamdani

Amro Aboukameel

Yousef Mzannar

...

2022/6/15

Molecular profiling of XPO1 inhibitor and gemcitabine-nab-paclitaxel combination in cellular and LSL-Kras G12D/+; Trp53 fl/+; Pdx1-Cre (KPC) pancreatic cancer model

bioRxiv

Md Hafiz Uddin

Amro Aboukameel

Yiwei Li

Husain Yar Khan

Rachel E Sexton

...

2022/3/9

Nuclear protein export inhibitor selinexor chemotherapy combination for pancreatic cancer therapy

Cancer Research

Md Hafiz Uddin

Sahar Bannoura

Yiwei Li

Husain Y Khan

Amro Aboukameel

...

2022/6/15

See List of Professors in Husain Yar Khan University(Wayne State University)

Co-Authors

H-index: 73
Aamir Ahmad

Aamir Ahmad

University of Alabama at Birmingham

H-index: 56
Ghulam Md Ashraf

Ghulam Md Ashraf

King AbdulAziz University

H-index: 34
Mohammad Fahad Ullah

Mohammad Fahad Ullah

University of Tabuk

H-index: 28
Naheed Banu

Naheed Banu

Qassim University

H-index: 21
Mohd Farhan

Mohd Farhan

King Faisal University

H-index: 14
Mohammed Najeeb Al Hallak, MD, MS

Mohammed Najeeb Al Hallak, MD, MS

Wayne State University

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