Holger Stark

About Holger Stark

Holger Stark, With an exceptional h-index of 61 and a recent h-index of 32 (since 2020), a distinguished researcher at Heinrich-Heine-Universität Düsseldorf, specializes in the field of Medicinal Chemistry, Drug Development.

His recent articles reflect a diverse array of research interests and contributions to the field:

Novel 4-nitroimidazole analogues: synthesis, in vitro biological evaluation, in silico studies, and molecular dynamics simulation

4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors

Histamine receptors in GtoPdb v. 2023.1

Thiazole derivatives as dual inhibitors of deoxyribonuclease I and 5-lipoxygenase: A promising scaffold for the development of neuroprotective drugs

Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch

Adriforant is a functional antagonist of histamine receptor 4 and attenuates itch and skin inflammation in mice

Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

Holger Stark Information

University

Position

/Germany

Citations(all)

15566

Citations(since 2020)

5368

Cited By

12098

hIndex(all)

61

hIndex(since 2020)

32

i10Index(all)

292

i10Index(since 2020)

158

Email

University Profile Page

Heinrich-Heine-Universität Düsseldorf

Google Scholar

View Google Scholar Profile

Holger Stark Skills & Research Interests

Medicinal Chemistry

Drug Development

Top articles of Holger Stark

Title

Journal

Author(s)

Publication Date

Novel 4-nitroimidazole analogues: synthesis, in vitro biological evaluation, in silico studies, and molecular dynamics simulation

Zeitschrift für Naturforschung C

Yaseen A Al-Soud

Sondos O Al-Sawakhnah

Raed A Al-Qawasmeh

Najim A Al-Masoudi

Ala’a H Al-Ahmad

...

2024/4/8

4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases

ACS Chemical Neuroscience

Beata Michalska

Marek Dzięgielewski

Justyna Godyń

Tobias Werner

Marek Bajda

...

2024/3/5

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors

Bioorganic & Medicinal Chemistry

Cecília MSQ Aranha

David Reiner-Link

Luisa R Leitzbach

Flavia B Lopes

Holger Stark

...

2023/1/15

Histamine receptors in GtoPdb v. 2023.1

IUPHAR/BPS Guide to Pharmacology CITE

Paul Chazot

Marlon Cowart

Hiroyuki Fukui

C Robin Ganellin

Ralf Gutzmer

...

2023/4/26

Thiazole derivatives as dual inhibitors of deoxyribonuclease I and 5-lipoxygenase: A promising scaffold for the development of neuroprotective drugs

Chemico-Biological Interactions

Ana Marković

Aleksandra Živković

Mariyana Atanasova

Irini Doytchinova

Bettina Hofmann

...

2023/8/25

Discovery of a new activator of Slack potassium channels with robust efficacy in models of histamine-independent and chronic itch

bioRxiv

Annika Balzulat

W Felix Zhu

Cathrin Flauaus

Victor Hernandez-Olmos

Jan Heering

...

2023

Adriforant is a functional antagonist of histamine receptor 4 and attenuates itch and skin inflammation in mice

European Journal of Pharmacology

Özge Uluckan

Sandro Bruno

Yichen Wang

Nathalie Wack

Jenny Wilzopolski

...

2023/4/15

Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain

Journal of Medicinal Chemistry

Katarzyna Szczepańska

Tadeusz Karcz

Maria Dichiara

Szczepan Mogilski

Justyna Kalinowska-Tłuścik

...

2023/7/7

Sphingolipid subtypes differentially control proinsulin processing and systemic glucose homeostasis

Nature Cell Biology

Kerstin Griess

Michael Rieck

Nadine Müller

Gergely Karsai

Sonja Hartwig

...

2023/1

Multitargeting Histamine H3 Receptor Ligands among Acetyl- and Propionyl-Phenoxyalkyl Derivatives

Molecules

Dorota Łażewska

Maria Kaleta

Paula Zaręba

Justyna Godyń

Mariam Dubiel

...

2023/3/3

Ceramides and ceramide synthases in cancer: Focus on apoptosis and autophagy

Javad Alizadeh

Simone C da Silva Rosa

Xiaohui Weng

Joadi Jacobs

Shahrokh Lorzadeh

...

2023/6/26

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer’s disease

Journal of Enzyme Inhibition and Medicinal Chemistry

Donia E Hafez

Mariam Dubiel

Gabriella La Spada

Marco Catto

David Reiner-Link

...

2023/12/31

Targeting UGCG overcomes resistance to lysosomal autophagy inhibition

Cancer discovery

Vaibhav Jain

Sandra L Harper

Amanda M Versace

Dylan Fingerman

Gregory Schuyler Brown

...

2023/2/6

Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo

Molecules

Agnieszka Olejarz-Maciej

Szczepan Mogilski

Tadeusz Karcz

Tobias Werner

Katarzyna Kamińska

...

2023/5/19

An orally available Cav2.2 calcium channel inhibitor for the treatment of neuropathic pain

British Journal of Pharmacology

Janine Kutzsche

Gustavo A Guzman

Antje Willuweit

Olaf Kletke

Esther Wollert

...

2023/12/29

Anti-inflammatory effects of new human histamine H3 receptor ligands with flavonoid structure on BV-2 neuroinflammation

Inflammation Research

Ewelina Honkisz-Orzechowska

Katarzyna Popiołek-Barczyk

Zuzanna Linart

Jadwiga Filipek-Gorzała

Anna Rudnicka

...

2023/2

Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

Pharmaceuticals

Marek Staszewski

Magdalena Iwan

Tobias Werner

Marek Bajda

Justyna Godyń

...

2023/4/30

N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease

Results in Chemistry

Tereza Hofmanova

Carolina Marques

Alfonso T García-Sosa

Óscar López

Luisa Leitzbach

...

2023/12/1

Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment

European Journal of Medicinal Chemistry

Radomir Juza

Iveta Vojtechova

Kristyna Stefkova-Mazochova

Wim Dehaen

Tomas Petrasek

...

2022/3/15

Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK pathway

Leukemia

M Hanief Sofi

Linlu Tian

Steven Schutt

Imran Khan

Hee-Jin Choi

...

2022/7

See List of Professors in Holger Stark University(Heinrich-Heine-Universität Düsseldorf)