Hector Keun

Hector Keun

Imperial College London

H-index: 63

Europe-United Kingdom

About Hector Keun

Hector Keun, With an exceptional h-index of 63 and a recent h-index of 37 (since 2020), a distinguished researcher at Imperial College London, specializes in the field of metabolic profiling, toxicology, tumour metabolism, NMR spectroscopy, pattern recognition.

His recent articles reflect a diverse array of research interests and contributions to the field:

Safety and preliminary efficacy of pembrolizumab following trans-arterial chemoembolization for hepatocellular carcinoma: the PETAL phase Ib study.

Abstract B096: Targeting RNA splicing factor RBM39 improves therapy responses in ovarian high-grade serous carcinoma

Corrigendum to" In-utero and childhood chemical exposome in six European mother-child cohorts"[Environ. Int. 121 (Part 1)(2018) 751-763]

Hyperacetylated histone H4 is a source of carbon contributing to lipid synthesis

Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome

Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma

Cobalt-Doped g-C3N4 Nanosheets for One-Pot Synthesis of Imines under Mild Conditions

Chemical Tools for Profiling the Intracellular ADP-ribosylated Proteome

Hector Keun Information

University

Position

Professor of Biochemistry

Citations(all)

14907

Citations(since 2020)

5687

Cited By

11441

hIndex(all)

63

hIndex(since 2020)

37

i10Index(all)

146

i10Index(since 2020)

119

Email

University Profile Page

Imperial College London

Google Scholar

View Google Scholar Profile

Hector Keun Skills & Research Interests

metabolic profiling

toxicology

tumour metabolism

NMR spectroscopy

pattern recognition

Top articles of Hector Keun

Title

Journal

Author(s)

Publication Date

Safety and preliminary efficacy of pembrolizumab following trans-arterial chemoembolization for hepatocellular carcinoma: the PETAL phase Ib study.

Clinical Cancer Research

David J Pinato

Antonio D'Alessio

Claudia Angela Maria Fulgenzi

Alexandra Emilia Schlaak

Ciro Celsa

...

2024/4/5

Abstract B096: Targeting RNA splicing factor RBM39 improves therapy responses in ovarian high-grade serous carcinoma

Cancer Research

Yuewei Xu

Sarah Spear

Yurui Ma

Marc Lorentzen

Michael Gruet

...

2024/3/4

Corrigendum to" In-utero and childhood chemical exposome in six European mother-child cohorts"[Environ. Int. 121 (Part 1)(2018) 751-763]

Environment International

Line Småstuen Haug

Amrit Kaur Sakhi

Enrique Cequier

Maribel Casas

Léa Maitre

...

2024/3

Hyperacetylated histone H4 is a source of carbon contributing to lipid synthesis

The EMBO Journal

Evelina Charidemou

Roberta Noberini

Chiara Ghirardi

Polymnia Georgiou

Panayiota Marcou

...

2024/2/21

Blurred lines: Crossing the boundaries between the chemical exposome and the metabolome

Cristina Balcells

Yitao Xu

Rubén Gil-Solsona

Léa Maitre

Pablo Gago-Ferrero

...

2024/2/1

Pharmacological depletion of RNA splicing factor RBM39 by indisulam synergizes with PARP inhibitors in high-grade serous ovarian carcinoma

Cell Reports

Yuewei Xu

Sarah Spear

Yurui Ma

Marc P Lorentzen

Michael Gruet

...

2023/10/31

Cobalt-Doped g-C3N4 Nanosheets for One-Pot Synthesis of Imines under Mild Conditions

CLINICAL CANCER RESEARCH

Sarah Halford

Gareth J Veal

Stephen R Wedge

Geoffrey S Payne

Chris M Bacon

...

2023/4/15

Chemical Tools for Profiling the Intracellular ADP-ribosylated Proteome

bioRxiv

Simeon D Draganov

Michael J Gruet

Daniel Conole

Cristina Balcells

Alexandros P Siskos

...

2023

P-179 Altered lipid metabolism in IMiD/CELMoD resistant multiple myeloma confers novel and targetable vulnerabilities

Clinical Lymphoma Myeloma and Leukemia

Sarah Bird

Yitao Xu

Fernando Sialana

Marco Licciardello

Harvey Che

...

2023/9/1

A phase I dose-escalation study of AZD3965, an oral monocarboxylate transporter 1 inhibitor, in patients with advanced cancer

Clinical Cancer Research

Sarah Halford

Gareth J Veal

Stephen R Wedge

Geoffrey S Payne

Chris M Bacon

...

2023/4/14

Heme oxygenase-1 expressing omental macrophages as a therapeutic target in ovarian high grade serous carcinoma

bioRxiv

Sarah Spear

Olivia Le Saux

Hasan B Mirza

Katie Tyson

Jasmine Bickel

...

2023

Metabolomics and the exposome

Frontiers in Public Health

Alexandros P Siskos

Hector C Keun

Benedikt Warth

Rachel S Kelly

Lea Maitre

2023/6/28

Childhood exposure to non-persistent endocrine disrupting chemicals and multi-omic profiles: A panel study

Environment International

Lorenzo Fabbri

Ronan Garlantézec

Karine Audouze

Mariona Bustamante

Ángel Carracedo

...

2023/3/1

Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort

Elife

Oliver Robinson

ChungHo E Lau

Sungyeon Joo

Sandra Andrusaityte

Eva Borras

...

2023/6/6

Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts

BMC medicine

Joseph A Rothwell

Jelena Bešević

Niki Dimou

Marie Breeur

Neil Murphy

...

2023/2/28

RBM39: A druggable metabolic sensor linking RNA splicing, transcriptional regulation, and metabolic reprogramming in cancer

Molecular Cell

Hector C Keun

Anke Nijhuis

2023/12/7

miR-22-enriched breast cancer cells display repressed glycolytic metabolism, increased glycogen synthesis, and reduced survival in low glucose conditions

Molecular Biology Reports

Costas Koufaris

Margarita E Papandreou

James K Ellis

Vicky Nicolaidou

Hector C Keun

2023/6

The potential and challenges of targeting MTAP-negative cancers beyond synthetic lethality

Chandler Bray

Cristina Balcells

Iain A McNeish

Hector C Keun

2023

Urinary metabolic biomarkers of diet quality in European children are associated with metabolic health

Elife

Nikos Stratakis

Alexandros P Siskos

Eleni Papadopoulou

Anh N Nguyen

Yinqi Zhao

...

2022/1/25

RSK4 inhibition promotes pseudo-hypoxic metabolic responses in lung adenocarcinoma

Cancer Research

Lucksamon Thamlikitkul

Peng Chai

Cristina Balcells Nadal

Rajat Roy

Xiao-Ming Sun

...

2022/6/15

See List of Professors in Hector Keun University(Imperial College London)

Co-Authors

H-index: 166
Jeremy K Nicholson

Jeremy K Nicholson

Murdoch University

H-index: 144
Elaine Holmes

Elaine Holmes

Imperial College London

H-index: 97
R.C.H. Vermeulen

R.C.H. Vermeulen

Universiteit Utrecht

H-index: 94
Ian D Wilson

Ian D Wilson

Imperial College London

H-index: 88
Justin Stebbing

Justin Stebbing

Imperial College London

H-index: 60
Tim Ebbels

Tim Ebbels

Imperial College London

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