Harmen J. Bussemaker
Columbia University in the City of New York
H-index: 45
North America-United States
Top articles of Harmen J. Bussemaker
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Predicting the DNA binding specificity of mutated transcription factors using family-level biophysically interpretable machine learning | bioRxiv | Shaoxun Liu Pilar Gomez-Alcala Christ Leemans William J Glassford Richard S Mann | 2024 |
Identifying genetic regulatory variants that affect transcription factor activity | Cell Genomics | Xiaoting Li Tuuli Lappalainen Harmen J Bussemaker | 2023/9/13 |
Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR | Nucleic Acids Research | Vincent D FitzPatrick Christ Leemans Joris van Arensbergen Bas van Steensel Harmen J Bussemaker | 2023/6/23 |
Emerging questions in transcriptional regulation | Cell Systems | Elphege P Nora Stein Aerts Patricia J Wittkopp Harmen J Bussemaker Martha Bulyk | 2023/4/19 |
Benchmarking DNA binding affinity models using allele-specific transcription factor binding data | bioRxiv | Xiaoting Li Lucas AN Melo Harmen J Bussemaker | 2023 |
Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements | Nucleic Acids Research | Max Trauernicht Chaitanya Rastogi Stefano G Manzo Harmen J Bussemaker Bas van Steensel | 2023/10/13 |
Transcription factor paralogs orchestrate alternative gene regulatory networks by context-dependent cooperation with multiple cofactors | Nature Communications | Siqian Feng Chaitanya Rastogi Ryan Loker William J Glassford H Tomas Rube | 2022/7/1 |
Transcription factor regulation of eQTL activity across individuals and tissues | PLoS Genetics | Elise D Flynn Athena L Tsu Silva Kasela Sarah Kim-Hellmuth Francois Aguet | 2022/1/31 |
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning | Nature Biotechnology | H Tomas Rube Chaitanya Rastogi Siqian Feng Judith F Kribelbauer Allyson Li | 2022/10 |
Probing molecular specificity with deep sequencing and biophysically interpretable machine learning | bioRxiv | H Tomas Rube Chaitanya Rastogi Siqian Feng Judith F Kribelbauer Allyson Li | 2021/7/1 |
Toward a Mechanistic Understanding of DNA Methylation Readout by Transcription Factors | Judith F Kribelbauer Xiang-Jun Lu Remo Rohs Richard S Mann Harmen J Bussemaker | 2020/3/13 | |
Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes | Nucleic Acids Research | Liyang Zhang H Tomas Rube Christopher A Vakulskas Mark A Behlke Harmen J Bussemaker | 2020/5/21 |
Context-dependent gene regulation by homeodomain transcription factor complexes revealed by shape-readout deficient proteins | Molecular cell | Judith F Kribelbauer Ryan E Loker Siqian Feng Chaitanya Rastogi Namiko Abe | 2020/4/2 |
Co-Authors
