Hans-Ulrich Klein

About Hans-Ulrich Klein

Hans-Ulrich Klein, With an exceptional h-index of 42 and a recent h-index of 31 (since 2020), a distinguished researcher at Columbia University in the City of New York, specializes in the field of Computational Neurology, Bioinformatics, Neuroinflammation.

His recent articles reflect a diverse array of research interests and contributions to the field:

ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease

Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities

A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis

Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

demuxmix: Demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

Proteome-wide discovery of cortical proteins that may provide motor resilience to offset the negative effects of pathologies in older adults

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory …

Mitochondrial respiratory chain protein co-regulation in the human brain

Hans-Ulrich Klein Information

University

Position

Columbia University Medical Center

Citations(all)

8611

Citations(since 2020)

5196

Cited By

5578

hIndex(all)

42

hIndex(since 2020)

31

i10Index(all)

69

i10Index(since 2020)

58

Email

University Profile Page

Google Scholar

Hans-Ulrich Klein Skills & Research Interests

Computational Neurology

Bioinformatics

Neuroinflammation

Top articles of Hans-Ulrich Klein

ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease

Journal of Neuroscience

2024/1/17

Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities

Neurology

2024/1/9

A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis

Biological Psychiatry

2023/12/21

Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease

Nature Communications

2023/11

demuxmix: Demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models

Bioinformatics

2023/8/1

Hans-Ulrich Klein
Hans-Ulrich Klein

H-Index: 30

Proteome-wide discovery of cortical proteins that may provide motor resilience to offset the negative effects of pathologies in older adults

The Journals of Gerontology: Series A

2023/3/1

Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory …

Alzheimer's & Dementia

2022/10

Mitochondrial respiratory chain protein co-regulation in the human brain

Heliyon

2022/5/1

Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans

Alzheimer's & Dementia

2022/4

Cortical proteins and individual differences in cognitive resilience in older adults

Neurology

2022/3/29

Novel Alzheimer disease risk loci and pathways in African American individuals using the African genome resources panel: a meta-analysis

JAMA neurology

2021/1/1

Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome

Nature communications

2021/12/6

Hans-Ulrich Klein
Hans-Ulrich Klein

H-Index: 30

Yiyi Ma
Yiyi Ma

H-Index: 13

Jia Liu
Jia Liu

H-Index: 5

Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue

Nature communications

2021/12/2

Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain

Molecular neurodegeneration

2021/12

The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes

Neurobiology of Disease

2021/9/1

Cortical proteins may provide motor resilience in older adults

Scientific reports

2021/5/28

A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies

Translational psychiatry

2021/1/14

BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology

Molecular neurodegeneration

2020/12

Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms

2020/9

Genetics of gene expression in the aging human brain reveal TDP-43 proteinopathy pathophysiology

Neuron

2020/8/5

See List of Professors in Hans-Ulrich Klein University(Columbia University in the City of New York)

Co-Authors

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