Graham Packham

Graham Packham

University of Southampton

H-index: 78

Europe-United Kingdom

About Graham Packham

Graham Packham, With an exceptional h-index of 78 and a recent h-index of 36 (since 2020), a distinguished researcher at University of Southampton,

His recent articles reflect a diverse array of research interests and contributions to the field:

Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL

B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells

Editor's Note: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance

Dataset for thesis titled: B-Cell receptor induced autophagy and phagocytosis in chronic lymphocytic leukaemia

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells

BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells

Synthesis of Carboxamide‐Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia

Graham Packham Information

University

Position

___

Citations(all)

17381

Citations(since 2020)

4627

Cited By

14342

hIndex(all)

78

hIndex(since 2020)

36

i10Index(all)

177

i10Index(since 2020)

107

Email

University Profile Page

University of Southampton

Google Scholar

View Google Scholar Profile

Top articles of Graham Packham

Title

Journal

Author(s)

Publication Date

Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL

Leukemia

Dean Bryant

Lindsay Smith

Karly Rai Rogers-Broadway

Laura Karydis

Jeongmin Woo

...

2023/7

B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells

Cellular Signalling

Joe Taylor

Sarah Wilmore

Sophie Marriot

Karly-Rai Rogers-Broadway

Rachel Fell

...

2022/6/1

Editor's Note: miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance

Cancer Research

Lei Zhang

Karen Pickard

Veronika Jenei

Marc D Bullock

Amanda Bruce

...

2022/4/15

Dataset for thesis titled: B-Cell receptor induced autophagy and phagocytosis in chronic lymphocytic leukaemia

Annabel Minton

Graham Packham

David Tumbarello

Andrew Steele

Lindsay D Smith

2022

Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

Blood, The Journal of the American Society of Hematology

Zhenghao Chen

Helga Simon-Molas

Gaspard Cretenet

Beatriz Valle-Argos

Lindsay D Smith

...

2022/8/11

B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells

Exploration of targeted anti-tumor therapy

Annabel R Minton

Lindsay D Smith

Dean J Bryant

Jonathan C Strefford

Francesco Forconi

...

2022

BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells

Cellular Signalling

Rachael Arthur

Alexander Wathen

Elizabeth A Lemm

Freda K Stevenson

Francesco Forconi

...

2022/8/1

Synthesis of Carboxamide‐Containing Tranylcypromine Analogues as LSD1 (KDM1A) Inhibitors Targeting Acute Myeloid Leukemia

ChemMedChem

Maria Teresa Borrello

Hanae Benelkebir

Adam Lee

Chak Hin Tam

Manar Shafat

...

2021/4/20

Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior

Blood, The Journal of the American Society of Hematology

Giorgia Chiodin

Joel D Allen

Dean J Bryant

Philip Rock

Enrica A Martino

...

2021/10/28

V-ATPase inhibition decreases mutant androgen receptor activity in castrate-resistant prostate cancer

Molecular cancer therapeutics

Bradleigh Whitton

Haruko Okamoto

Matthew Rose-Zerilli

Graham Packham

Simon J Crabb

2021/4/1

Kinobead profiling reveals reprogramming of BCR signaling in response to therapy within primary CLL cells

Clinical Cancer Research

Adam J Linley

Laura I Karydis

Anil K Mondru

Annalisa D'Avola

Humood Al Shmrany

...

2021/10/15

Synthesis of carboxamides tranylcypromine analogues as LSD1 (KDM1A) inhibitors for AML

Teresa Borrello

Chak Hin Tam

Manar Shafat

Stuart Rushworth

Kristian Bowles

...

2021/1/27

Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells

Cellular and Molecular Life Sciences

Sarah Wilmore

Karly-Rai Rogers-Broadway

Joe Taylor

Elizabeth Lemm

Rachel Fell

...

2021/9

KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas

Blood, The Journal of the American Society of Hematology

James Heward

Lola Koniali

Annalisa D’Avola

Karina Close

Alison Yeomans

...

2021/8/5

DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity

Scientific Reports

Beatriz Valle-Argos

Giorgia Chiodin

Dean J Bryant

Joe Taylor

Elizabeth Lemm

...

2021/6/3

Targeting Metabolic Alterations in CLL Microenvironment; Inhibition of Glutamine Import Attenuates Venetoclax Resistance

Blood

Zhenghao Chen

Helga Simon-Molas

Gaspard Cretenet

Beatriz Valle-Argos

Francesco Forconi

...

2021/11/23

Targeted inhibition of mRNA translation initiation factors as a novel therapeutic strategy for mature B-cell neoplasms

Exploration of Targeted Anti-tumor Therapy

Joe Taylor

Alison M Yeomans

Graham Packham

2020

Upregulation of epithelial metallothioneins by metal-rich ultrafine particulate matter from an underground railway

Metallomics

Matthew Loxham

Jeongmin Woo

Akul Singhania

Natalie P Smithers

Alison Yeomans

...

2020/7

Development of PROTACs to address clinical limitations associated with BTK-targeted kinase inhibitor

Exploration of Targeted Anti-tumor Therapy

Rachael Arthur

Beatriz Valle-Argos

Andrew J Steele

Graham Packham

2020

Correction: Bidirectional linkage between the B-cell receptor and NOTCH1 in chronic lymphocytic leukemia and in Richter’s syndrome: therapeutic implications

Leukemia

Francesca Arruga

Valeria Bracciamà

Nicoletta Vitale

Tiziana Vaisitti

Katiuscia Gizzi

...

2020/6

See List of Professors in Graham Packham University(University of Southampton)