Graham MacLeod

Graham MacLeod

University of Toronto

H-index: 15

North America-Canada

About Graham MacLeod

Graham MacLeod, With an exceptional h-index of 15 and a recent h-index of 12 (since 2020), a distinguished researcher at University of Toronto, specializes in the field of Functional Genomics, Cell & Molecular Biology, Brain Tumor Biology, Drug Discovery.

His recent articles reflect a diverse array of research interests and contributions to the field:

PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma

A GENOME-WIDE CRISPR/CAS9 SCREENING IDENTIFIES GENETIC MODIFIERS OF ΑLPHA SYNUCLEIN AGGREGATES UPTAKE

Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes

A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans

Identification of Drug Resistance Mechanisms Using Genome-Wide CRISPR-Cas9CRISPR-Cas9 Screens

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

Graham MacLeod Information

University

Position

___

Citations(all)

3265

Citations(since 2020)

2700

Cited By

1531

hIndex(all)

15

hIndex(since 2020)

12

i10Index(all)

18

i10Index(since 2020)

13

Email

University Profile Page

University of Toronto

Google Scholar

View Google Scholar Profile

Graham MacLeod Skills & Research Interests

Functional Genomics

Cell & Molecular Biology

Brain Tumor Biology

Drug Discovery

Top articles of Graham MacLeod

Title

Journal

Author(s)

Publication Date

PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

bioRxiv

MONA ALQAZZAZ

Felipe Eduardo Ciamponi Sr

Jolene Caifeng Ho

Maxim I Maron

Manisha Yadav

...

2024

The CDK12 inhibitor SR-4835 functions as a molecular glue that promotes cyclin K degradation in melanoma

Cell Death Discovery

Thibault Houles

Jonathan Boucher

Geneviève Lavoie

Graham MacLeod

Sichun Lin

...

2023/12/16

A GENOME-WIDE CRISPR/CAS9 SCREENING IDENTIFIES GENETIC MODIFIERS OF ΑLPHA SYNUCLEIN AGGREGATES UPTAKE

IBRO Neuroscience Reports

Benoît Vanderperre

Amitha Muraleedharan

Frédérique Larroquette

Rony Chidiac

Charlotte Tardif

...

2023/10/1

Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

bioRxiv

Islam E Elkholi

Amélie Robert

Hellen Kuasne

Stanislav Drapela

Graham Macleod

...

2023/8/5

Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes

Science Advances

Xian Wang

Zheyuan Gong

Tiancong Wang

Junhui Law

Xin Chen

...

2023/3/29

A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans

bioRxiv

Benoit Vanderperre

Amitha Muraleedharan

Marie-France Dorion

Frederique Larroquette

Esther Del Cid Pellitero

...

2023

Identification of Drug Resistance Mechanisms Using Genome-Wide CRISPR-Cas9CRISPR-Cas9 Screens

Graham MacLeod

Nishani Rajakulendran

Stephane Angers

2022/7/23

A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy

EMBO Molecular Medicine

Rony Chidiac

Md Abedin

Graham Macleod

Andy Yang

Pierre E Thibeault

...

2021/7/7

The Mediator tail module cooperates with proneural factors to determine fate identity in Glioblastoma

bioRxiv

Moloud Ahmadi

Graham MacLeod

Nishani Rajakulendran

Milena Kosic

Andy Yang

...

2021/5/4

Gradient of developmental and injury response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Nature Cancer

Laura M Richards

Owen KN Whitley

Graham MacLeod

Florence MG Cavalli

Fiona J Coutinho

...

2021/2

Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival

Elife

Paul Guilhamon

Charles Chesnelong

Michelle M Kushida

Ana Nikolic

Divya Singhal

...

2021/1/11

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Nature communications

Léo Aubert

Neethi Nandagopal

Zachary Steinhart

Geneviève Lavoie

Sami Nourreddine

...

2020/7/24

Metabolic regulation of the epigenome drives lethal infantile ependymoma

Cell

Kulandaimanuvel Antony Michealraj

Sachin A Kumar

Leo JY Kim

Florence MG Cavalli

David Przelicki

...

2020/6/11

See List of Professors in Graham MacLeod University(University of Toronto)