Gabriela Alexe

Gabriela Alexe

Harvard University

H-index: 50

North America-United States

About Gabriela Alexe

Gabriela Alexe, With an exceptional h-index of 50 and a recent h-index of 37 (since 2020), a distinguished researcher at Harvard University, specializes in the field of Integrative Cancer Genomics, Breast Cancer, Logical Analysis of Data, Combinatorial Pattern Discovery, Scientific Computation.

His recent articles reflect a diverse array of research interests and contributions to the field:

ATM and PARP combined inhibition demonstrate synergistic antitumor efficacy in osteosarcoma models

The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia

Abstract PR004: SMARCAL1 is a selective dependency and a novel synthetic lethal target in ATRX/DAXX mutant ALT+ osteosarcoma and neuroblastoma

Combining menin and MEK inhibition to target poor prognostic KMT2A-rearranged RAS pathway-mutant acute leukemia

Transcriptional antagonism by CDK8 inhibition improves therapeutic efficacy of MEK inhibitors

The Splicing-Associated Network PAK1-Clk-SRRM1 Is a Critical Vulnerability to Overcome Chemoresistance in Acute Myeloid Leukemia

Identifying Targeted Therapies for CBFA2T3-GLIS2 Acute Myeloid Leukemia

DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

Gabriela Alexe Information

University

Position

Dana-Farber Cancer Institute / Harvard Medical School / Broad Institute of MIT and Harvard

Citations(all)

23935

Citations(since 2020)

9818

Cited By

18154

hIndex(all)

50

hIndex(since 2020)

37

i10Index(all)

85

i10Index(since 2020)

72

Email

University Profile Page

Harvard University

Google Scholar

View Google Scholar Profile

Gabriela Alexe Skills & Research Interests

Integrative Cancer Genomics

Breast Cancer

Logical Analysis of Data

Combinatorial Pattern Discovery

Scientific Computation

Top articles of Gabriela Alexe

Title

Journal

Author(s)

Publication Date

ATM and PARP combined inhibition demonstrate synergistic antitumor efficacy in osteosarcoma models

Cancer Research

Sona N Kocinsky

Janeala J Morsby

William C Wright

Monika Wierdl

Caroline S Wechsler

...

2024/3/22

The UBE2J2/UBE2K-MARCH5 ubiquitination machinery regulates apoptosis in response to venetoclax in acute myeloid leukemia

Leukemia

Shan Lin

Constanze Schneider

Angela H Su

Gabriela Alexe

David E Root

...

2024/2/16

Abstract PR004: SMARCAL1 is a selective dependency and a novel synthetic lethal target in ATRX/DAXX mutant ALT+ osteosarcoma and neuroblastoma

Cancer Research

Monika Wierdl

Jerrel L Catlett

Nicole Ocasio-Martinez

John D Johnson Jr

Amy Herman

...

2024/1/9

Combining menin and MEK inhibition to target poor prognostic KMT2A-rearranged RAS pathway-mutant acute leukemia

Blood

Nastassja Scheidegger

Gabriela Alexe

Delan Khalid

Rhonda E Ries

Jim Wang

...

2023/11/28

Transcriptional antagonism by CDK8 inhibition improves therapeutic efficacy of MEK inhibitors

Cancer research

Clare F Malone

Minjee Kim

Gabriela Alexe

Kathleen Engel

Alexandra B Forman

...

2023/1/18

The Splicing-Associated Network PAK1-Clk-SRRM1 Is a Critical Vulnerability to Overcome Chemoresistance in Acute Myeloid Leukemia

Blood

Camille Vaganay

Frank Ling

Lois M Kelly

Duong Ho Nhat

Antoine Forget

...

2023/11/28

Identifying Targeted Therapies for CBFA2T3-GLIS2 Acute Myeloid Leukemia

Blood

Fanny Gonzales

Shan Lin

Delan Khalid

Jana M Ellegast

Gabriela Alexe

...

2023/11/28

DHODH: a promising target in the treatment of T-cell acute lymphoblastic leukemia

Blood Advances

Amy N Sexauer

Gabriela Alexe

Karin Gustafsson

Elizabeth Zanetakos

Jelena Milosevic

...

2023/11/14

Functional Dissection of Cellular Programs to Uncover Novel Gene Dependencies in AML

Blood

Jana M Ellegast

Gabriela Alexe

Subha Baniya

Amanda Hamze

Audrey Taillon

...

2023/11/28

P410: COMBINING MENIN AND MEK INHIBITION TO TREAT CHILDREN WITH POOR PROGNOSTIC KMT2A-R RAS-MUTANT ACUTE LEUKEMIA

HemaSphere

Nastassja Scheidegger

Gabriela Alexe

Delan Khalid

Jennifer Perry

Scott Armstrong

...

2023/8/1

Abstract LB076: Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts

Cancer Research

Jana M Ellegast

Gabriela Alexe

Amanda Hamze

Shan Lin

Hannah J Uckelmann

...

2022/6/15

Breaking the pump: targeting the sodium-potassium pump as a therapeutic strategy in acute myeloid leukemia

Blood

Constanze Schneider

Hermes Spaink

Gabriela Alexe

Neekesh V Dharia

Ashleigh Meyer

...

2022/11/15

P455: BREAKING THE PUMP: TARGETING THE SODIUM-POTASSIUM PUMP AS A THERAPEUTIC STRATEGY IN ACUTE MYELOID LEUKEMIA

HemaSphere

Constanze Schneider

Hermes Spaink

Gabriela Alexe

Neekesh V Dharia

Delan Khalid

...

2022/6/1

Transition to a mesenchymal state in neuroblastoma confers resistance to anti-GD2 antibody via reduced expression of ST8SIA1

Nature cancer

Nathaniel W Mabe

Min Huang

Guillermo N Dalton

Gabriela Alexe

Daniel A Schaefer

...

2022/8

Abstract PR003: Lineage plasticity dictates responsiveness to anti-GD2 therapy in neuroblastoma

Cancer Research

Nathaniel W Mabe

Min Huang

Daniel A Schaefer

Guillermo N Dalton

Giulia Digiovanni

...

2022/12/1

Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts

Cancer discovery

Jana M Ellegast

Gabriela Alexe

Amanda Hamze

Shan Lin

Hannah J Uckelmann

...

2022/7/6

Cystine uptake inhibition potentiates front-line therapies in acute myeloid leukemia

Leukemia

Bryann Pardieu

Justine Pasanisi

Frank Ling

Reinaldo Dal Bello

Justine Penneroux

...

2022/6

DHODH: A Promising New Therapeutic Target in Pediatric T-ALL

Blood

Amy N Sexauer

Gabriela Alexe

Varsha Gandhi

Kimberly Stegmaier

David Sykes

2022/11/15

Mitochondrial dysfunction is a driver of SP-2509 drug resistance in ewing sarcoma

Molecular Cancer Research

E John Tokarsky

Jesse C Crow

Lillian M Guenther

John Sherman

Cenny Taslim

...

2022/7/6

The proteogenomic subtypes of acute myeloid leukemia

Cancer Cell

Ashok Kumar Jayavelu

Sebastian Wolf

Florian Buettner

Gabriela Alexe

Björn Häupl

...

2022/3/14

See List of Professors in Gabriela Alexe University(Harvard University)

Co-Authors

H-index: 186
Todd Golub

Todd Golub

Harvard University

H-index: 87
PABLO TAMAYO

PABLO TAMAYO

University of California, San Diego

H-index: 85
Anant Madabhushi

Anant Madabhushi

Case Western Reserve University

H-index: 82
William A. Weiss

William A. Weiss

University of California, San Francisco

H-index: 67
Shridar Ganesan

Shridar Ganesan

Rutgers, The State University of New Jersey

H-index: 56
Gyan Bhanot

Gyan Bhanot

Rutgers, The State University of New Jersey

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