Frederic Kaye

Frederic Kaye

University of Florida

H-index: 57

North America-United States

About Frederic Kaye

Frederic Kaye, With an exceptional h-index of 57 and a recent h-index of 29 (since 2020), a distinguished researcher at University of Florida,

His recent articles reflect a diverse array of research interests and contributions to the field:

PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer

Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032)

Elucidating the significance of amphiregulin and its implications for EGFR inhibition strategies in LKB1-mutant NSCLC

Discovery of a first-in-class multifunctional TYMS non-classical antifolate inhibitors with potent in vivo activity that prolongs survival

TYMS as a novel target for AAV-based therapy

PROTAC therapy as a new targeted therapy for lung cancer

Disparities Contributing to Late-Stage Diagnosis of Lung, Colorectal, Breast, and Cervical Cancers: Rural and Urban Poverty in Florida

A phase II randomized therapeutic optimization trial for patients with refractory metastatic colorectal cancer using circulating tumor DNA (ctDNA): Rapid 1 trial.

Frederic Kaye Information

University

Position

___

Citations(all)

32705

Citations(since 2020)

8598

Cited By

27492

hIndex(all)

57

hIndex(since 2020)

29

i10Index(all)

117

i10Index(since 2020)

64

Email

University Profile Page

Google Scholar

Top articles of Frederic Kaye

Title

Journal

Author(s)

Publication Date

PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer

Cells

Sajid Khan

Lin Cao

Janet Wiegand

Peiyi Zhang

Maria Zajac-Kaye

...

2024/3/17

Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032)

Journal for Immunotherapy of Cancer

Margaret Callahan

Asim Amin

Frederic J Kaye

Michael A Morse

Matthew H Taylor

...

2024

Elucidating the significance of amphiregulin and its implications for EGFR inhibition strategies in LKB1-mutant NSCLC

Cancer Research

Xzaviar Kaymar Solone

Xin Zhou

Mu Yu

Jennifer W Li

Finn Rimay

...

2024/3/22

Discovery of a first-in-class multifunctional TYMS non-classical antifolate inhibitors with potent in vivo activity that prolongs survival

Cancer Research

Peter Elias Dib

Maria Guijarro

Patrick Kellish

Nick Paciaroni

Akbar Nawab

...

2023/4/4

TYMS as a novel target for AAV-based therapy

Cancer Research

Vinod Vijayakurup

Benjamin Meyer

Akbar Nawab

Frederic J Kaye

Maria V Guijarro

...

2023/4/4

PROTAC therapy as a new targeted therapy for lung cancer

Jennifer W Li

Guangrong Zheng

Frederic J Kaye

Lizi Wu

2023/3/1

Disparities Contributing to Late-Stage Diagnosis of Lung, Colorectal, Breast, and Cervical Cancers: Rural and Urban Poverty in Florida

Cancers

Jaclyn M Hall

Rahma S Mkuu

Hee Deok Cho

Jennifer N Woodard

Frederic J Kaye

...

2023/10/31

A phase II randomized therapeutic optimization trial for patients with refractory metastatic colorectal cancer using circulating tumor DNA (ctDNA): Rapid 1 trial.

Sherise C Rogers

Shu Wang

Ryan Michael Thomas

Brian Hemendra Ramnaraign

Jesus C Fabregas

...

2023/2/1

TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

Oncogene

Maria V Guijarro

Akbar Nawab

Peter Dib

Sandra Burkett

Xiaoping Luo

...

2023/6/6

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery

Sajid Khan

Patrick Kellish

Nick Connis

Dinesh Thummuri

Janet Wiegand

...

2023/1/2

First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival

JCI insight

Maria V Guijarro

Patrick C Kellish

Peter E Dib

Nicholas G Paciaroni

Akbar Nawab

...

2023/5/5

Effects of a yoga intervention on distress indicators among diverse women with gynecologic, gastrointestinal, and thoracic cancers.

Grace Ann Hanvey

Adaixa Padron

Elizabeth L Kacel

Kelsey C Bacharz

Dennie V Jones

...

2022/6/1

Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival

JCI insight

Vinod Vijayakurup

Kyungah Maeng

Hye Seung Lee

Benjamin Meyer

Sandra Burkett

...

2022/10/10

Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming—A New Mechanism for SCLC Chemoresistance Boosted by Nicotine

Cancers

Yuzhi Wang

Tengfei Bian

Lina Song

Yunhan Jiang

Zhiguang Huo

...

2022/5/2

First in class multifunctional non classical antifolates inhibits thymidylate synthase and extends survival in pancreatic cancer model

Cancer Research

Maria V Guijarro

Patrick C Kellish

Peter E Dib

Nicholas G Paciaroni

Akbar Nawab

...

2022/6/15

Managing stage 4 ameloblastoma with dual BRAF/MEK inhibition: A case report with 8-year clinical follow-up

Oral oncology

Zachary Abramson

Orrin L Dayton

Walter E Drane

William M Mendenhall

Frederic J Kaye

2022/5/1

A BCL-XL PROTAC degrader DT2216 synergizes with KRASG12C inhibitors for effectively treating KRASG12C-mutated cancers

Cancer Research

Sajid Khan

Janet Wiegand

Peiyi Zhang

Wanyi Hu

Dinesh Thummuri

...

2022/6/15

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

Journal of Hematology & Oncology

Sajid Khan

Janet Wiegand

Peiyi Zhang

Wanyi Hu

Dinesh Thummuri

...

2022/3/9

Personalised Lung Cancer Screening (PLuS) study to assess the importance of coexisting chronic conditions to clinical practice and policy: protocol for a multicentre …

BMJ open

Dejana Braithwaite

Shama D Karanth

Christopher G Slatore

Dongyu Zhang

Jiang Bian

...

2022/6/1

BCL-X

Sajid Khan

Janet Wiegand

Peiyi Zhang

Wanyi Hu

Dinesh Thummuri

...

2022

See List of Professors in Frederic Kaye University(University of Florida)