Fred W. van Leeuwen
Universiteit Maastricht
H-index: 64
Europe-Netherlands
Top articles of Fred W. van Leeuwen
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Altered ubiquitin signaling induces Alzheimer’s disease-like hallmarks in a three-dimensional human neural cell culture model | Nature Communications | Inbal Maniv Mahasen Sarji Anwar Bdarneh Alona Feldman Roi Ankawa | 2023/9/22 |
DOT1L regulates chromatin reorganization and gene expression during sperm differentiation | EMBO reports | Mélina Blanco Laila El Khattabi Clara Gobé Marion Crespo Manon Coulée | 2023/6/5 |
Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting | Nature structural & molecular biology | Ineke Brouwer Emma Kerklingh Fred van Leeuwen Tineke L Lenstra | 2023/5 |
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability | Cell reports | Lisa Willemsen Koen HM Prange Annette E Neele Cindy PAA Van Roomen Marion Gijbels | 2022/11/22 |
DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro | Frontiers in Genetics | Eliza Mari Kwesi-Maliepaard Muddassir Malik Tibor Van Welsem Remco Van Doorn Maarten H Vermeer | 2022/11/8 |
The histone methyltransferase SETD2 negatively regulates cell size | Journal of Cell Science | Thom M Molenaar Muddassir Malik Joana Silva Ning Qing Liu Judith HI Haarhuis | 2022/10/1 |
SETD2: from chromatin modifier to multipronged regulator of the genome and beyond | Thom M Molenaar Fred van Leeuwen | 2022/6 | |
Signals for antigen-independent differentiation of memory CD8+ T cells | Eliza Mari Kwesi-Maliepaard Heinz Jacobs Fred van Leeuwen | 2021/10 | |
Histone methyltransferase DOT1L regulates macrophage inflammatory responses and lipid metabolism | Atherosclerosis | L Willemsen AE Neele KHM Prange DAM Lotgerink Bruinenberg M Den Toom | 2021/8/1 |
Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies | Scientific reports | Leonie Kollenstart Sophie C van der Horst Kees Vreeken George MC Janssen Fabrizio Martino | 2021/6/17 |
Histone methyltransferase DOT1L controls state‐specific identity during B cell differentiation | EMBO reports | Muhammad Assad Aslam Mir Farshid Alemdehy Eliza Mari Kwesi‐Maliepaard Fitriari Izzatunnisa Muhaimin Marieta Caganova | 2021/2/3 |
SETD2 negatively regulates cell size through its catalytic activity and SRI domain | bioRxiv | Thom M Molenaar Eliza Mari Kwesi-Maliepaard Joana Silva Muddassir Malik William J Faller | 2021/10/31 |
Chromatin modified in a molecular reaction chamber | Nick Gilbert Fred van Leeuwen | 2020/3/26 | |
Application of recombination-induced tag exchange (RITE) to study histone dynamics in human cells | Epigenetics | Thom M Molenaar Marc Pagès-Gallego Vanessa Meyn Fred van Leeuwen | 2020/9/1 |
Strategy for development of site-specific ubiquitin antibodies | Frontiers in Chemistry | Ila Van Kruijsbergen Monique PC Mulder Michael Uckelmann Tibor Van Welsem John De Widt | 2020/2/21 |
The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8+ T cells | Proceedings of the National Academy of Sciences | Eliza Mari Kwesi-Maliepaard Muhammad Assad Aslam Mir Farshid Alemdehy Teun van den Brand Chelsea McLean | 2020/8/25 |
A reaction chamber for chromatin modification | Nature | Nick Gilbert Fred van Leeuwen | 2020 |
Expression of mutant ubiquitin and proteostasis impairment in Kii Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex brains | Journal of Neuropathology & Experimental Neurology | Bert M Verheijen Satoru Morimoto Ryogen Sasaki Kiyomitsu Oyanagi Yasumasa Kokubo | 2020/8/1 |
Activation of the unfolded protein response and proteostasis disturbance in parkinsonism-dementia of Guam | Journal of Neuropathology & Experimental Neurology | Bert M Verheijen Celina Lussier Cora Müller-Hübers Ralph M Garruto Kiyomitsu Oyanagi | 2020/1/1 |
A genetic interaction map centered on cohesin reveals auxiliary factors involved in sister chromatid cohesion in S. cerevisiae | Journal of cell science | Su Ming Sun Amandine Batté Mireille Elmer Sophie C van Der Horst Tibor van Welsem | 2020/5/15 |
