Fred Guengerich
Vanderbilt University
H-index: 175
North America-United States
Top articles of Fred Guengerich
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target | Journal of Medicinal Chemistry | Muthuraj Prakash Yukihiro Itoh Yoshie Fujiwara Yukari Takahashi Yuri Takada | 2021/11/3 |
In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells | Chemical Research in Toxicology | Shotaro Uehara Norie Murayama Yuichiro Higuchi Makiko Shimizu Hiroshi Suemizu | 2024/4/16 |
Formation of potentially toxic metabolites of drugs in reactions catalyzed by human drug-metabolizing enzymes | Slobodan P Rendic F Peter Guengerich | 2024/3/23 | |
Proteomics, modeling, and fluorescence assays delineate cytochrome b5 residues involved in binding and stimulation of cytochrome P450 17A1 17, 20-lyase | Journal of Biological Chemistry | Yasuhiro Tateishi Stephany N Webb Bian Li Lu Liu Kristie Lindsey Rose | 2024/3/1 |
Oxygen‐18 Labeling Reveals a Mixed Fe− O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation | Angewandte Chemie | Kevin D McCarty Yasuhiro Tateishi Tatiana Y Hargrove Galina I Lepesheva F Peter Guengerich | 2024/2/26 |
Ninety-eight semesters of cytochrome P450 enzymes and related topics—What have I taught and learned? | Journal of Biological Chemistry | F Peter Guengerich | 2024/2/1 |
Oxygen-18 Labeling Defines a Ferric Peroxide (Compound 0) Mechanism in the Oxidative Deformylation of Aldehydes by Cytochrome P450 2B4 | ACS catalysis | Yasuhiro Tateishi Kevin D McCarty Martha V Martin F Peter Guengerich | 2024/1/31 |
Principles of Xenobiotic Metabolism (Biotransformation) | Mirza Bojić Željko Debeljak F Peter Guengerich | 2024/1/5 | |
The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive | Journal of Biological Chemistry | Kevin D McCarty Lu Liu Yasuhiro Tateishi Hannah L Wapshott-Stehli F Peter Guengerich | 2023/11/24 |
Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1 | Journal of Biological Chemistry | Kevin D McCarty Molly E Sullivan Yasuhiro Tateishi Tatiana Y Hargrove Galina I Lepesheva | 2023/7/1 |
Basis for the discrimination of supercoil handedness during DNA cleavage by human and bacterial type II topoisomerases | Nucleic Acids Research | Jeffrey Y Jian Kevin D McCarty Jo Ann W Byl F Peter Guengerich Keir C Neuman | 2023/5/8 |
The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants in vitro | Xenobiotica | Michiaki Kojima Kanami Machida Sumie Cho Daichi Watanabe Hiroyuki Seki | 2023/5/4 |
FEMA GRAS assessment of natural flavor complexes: Lemongrass oil, chamomile oils, citronella oil and related flavoring ingredients | Food and Chemical Toxicology | Thomas J Rosol Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham | 2023/5/1 |
FEMA GRAS assessment of derivatives of basil, nutmeg, parsley, tarragon and related allylalkoxybenzene-containing natural flavor complexes | Food and Chemical Toxicology | Jeanne M Davidsen Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham | 2023/5/1 |
Identification of Three Human POLH Germline Variants Defective in Complementing the UV-and Cisplatin-Sensitivity of POLH-Deficient Cells | International Journal of Molecular Sciences | Mina Yeom Jin-Kyung Hong Joo-Ho Shin Yunjong Lee Frederick Peter Guengerich | 2023/3/8 |
Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1) | Journal of inorganic biochemistry | Sung-Gyu Lee Vitchan Kim Gyu-Hyeong Lee Changmin Kim Eunseo Jeong | 2023/3/1 |
The Importance of Biotransformation | F Peter Guengerich | 2023/1/1 | |
Cytochrome P450 enzymes as drug targets in human disease | Drug Metabolism and Disposition | F Peter Guengerich | 2023/1/1 |
Steroid 17α-hydroxylase/17, 20-lyase (cytochrome P450 17A1) | F Peter Guengerich Kevin D McCarty Yasuhiro Tateishi Lu Liu | 2023/1/1 | |
Direct addition of flavors, including taste and flavor modifiers | Ivonne MCM Rietjens Samuel M Cohen Gerhard Eisenbrand Shoji Fukushima Nigel J Gooderham | 2023/1/1 |
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