Frank J Bruggeman

Frank J Bruggeman

Vrije Universiteit Amsterdam

H-index: 46

Europe-Netherlands

About Frank J Bruggeman

Frank J Bruggeman, With an exceptional h-index of 46 and a recent h-index of 30 (since 2020), a distinguished researcher at Vrije Universiteit Amsterdam, specializes in the field of Systems biology, computational biology, biophysics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Understanding and computational design of genetic circuits of metabolic networks

Trade‐offs between the instantaneous growth rate and long‐term fitness: consequences for microbial physiology and predictive computational models

Is distance from equilibrium a good indicator for a reaction’s flux control?

Growth consequences of the inhomogeneous organization of the bacterial cytoplasm

Effective bet-hedging through growth rate dependent stability

Whole-cell metabolic control analysis

A temperature-sensitive metabolic valve and a transcriptional feedback loop drive rapid homeoviscous adaptation in Escherichia coli

Understanding spatiotemporal coupling of gene expression using single molecule RNA imaging technologies

Frank J Bruggeman Information

University

Position

Professor

Citations(all)

7883

Citations(since 2020)

2745

Cited By

6301

hIndex(all)

46

hIndex(since 2020)

30

i10Index(all)

98

i10Index(since 2020)

63

Email

University Profile Page

Vrije Universiteit Amsterdam

Google Scholar

View Google Scholar Profile

Frank J Bruggeman Skills & Research Interests

Systems biology

computational biology

biophysics

Top articles of Frank J Bruggeman

Title

Journal

Author(s)

Publication Date

Understanding and computational design of genetic circuits of metabolic networks

Alicia Berkvens

Luis Salinas

Maaike Remeijer

Robert Planqué

Bas Teusink

...

2024/4/25

Trade‐offs between the instantaneous growth rate and long‐term fitness: consequences for microbial physiology and predictive computational models

Frank J Bruggeman

Bas Teusink

Ralf Steuer

2023/10

Is distance from equilibrium a good indicator for a reaction’s flux control?

BioSystems

David D van Niekerk

Erik Rust

Frank Bruggeman

Hans V Westerhoff

Jacky L Snoep

2023/10/1

Growth consequences of the inhomogeneous organization of the bacterial cytoplasm

bioRxiv

Johan H van Heerden

Alicia M Berkvens

Daan H de Groot

Frank J Bruggeman

2023

Effective bet-hedging through growth rate dependent stability

Proceedings of the National Academy of Sciences

Daan H de Groot

Age J Tjalma

Frank J Bruggeman

Erik van Nimwegen

2023/2/21

Whole-cell metabolic control analysis

Biosystems

Frank J Bruggeman

Maaike Remeijer

Maarten Droste

Luis Salinas

Meike Wortel

...

2023/12/1

A temperature-sensitive metabolic valve and a transcriptional feedback loop drive rapid homeoviscous adaptation in Escherichia coli

bioRxiv

Loles Hoogerland

Stefan van den Berg

Adja Zoumaro-Djayoon

Esther Geurken

Flora Yang

...

2023

Understanding spatiotemporal coupling of gene expression using single molecule RNA imaging technologies

Alan Gerber

Sander van Otterdijk

Frank J Bruggeman

Evelina Tutucci

2023/10/20

Integrative biology of persister cell formation: molecular circuitry, phenotypic diversification and fitness effects

Alicia Berkvens

Priyanka Chauhan

Frank J Bruggeman

2022/9/14

Selection for Cell Yield Does Not Reduce Overflow Metabolism in Escherichia coli

Molecular biology and evolution

Iraes Rabbers

Willi Gottstein

Adam M Feist

Bas Teusink

Frank J Bruggeman

...

2022/1/1

Escherichia coli robustly expresses ATP synthase at growth rate‐maximizing concentrations

The FEBS Journal

Iraes Rabbers

Frank J Bruggeman

2022/8

Coupling phenotype stability to growth rate overcomes limitations of bet-hedging strategies

BioRxiv

Daan H de Groot

Age J Tjalma

Frank J Bruggeman

Erik van Nimwegen

2022/4/13

Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors

Journal of cell science

Sergei Chavez-Abiega

Max LB Grönloh

Theodorus WJ Gadella Jr

Frank J Bruggeman

Joachim Goedhart

2022/3/15

Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies

Nature communications

Ibrahim E Elsemman

Angelica Rodriguez Prado

Pranas Grigaitis

Manuel Garcia Albornoz

Victoria Harman

...

2022/2/10

Homeostasis

Cell Systems

Inna Slutsky

Gerhard Schratt

Guy-Bart Stan

Sacha Nelson

Frank J Bruggeman

2021/12/15

Heterogeneity and dynamics of ERK and Akt activation by G protein-coupled receptors depend on the activated heterotrimeric G proteins

bioRxiv

Sergei Chavez-Abiega

Max LB Grönloh

TWJ Gadella Jr

Frank J Bruggeman

J Goedhart

2021/7/27

A yeast FRET biosensor enlightens cAMP signaling

Molecular Biology of the Cell

Dennis Botman

Tom G O’Toole

Joachim Goedhart

Frank J Bruggeman

Johan H van Heerden

...

2021/6/15

Unlocking elementary conversion modes: Ecmtool unveils all capabilities of metabolic networks

Patterns

Tom J Clement

Erik B Baalhuis

Bas Teusink

Frank J Bruggeman

Robert Planqué

...

2021/1/8

The common message of constraint-based optimization approaches: overflow metabolism is caused by two growth-limiting constraints

Daan H De Groot

Julia Lischke

Riccardo Muolo

Robert Planqué

Frank J Bruggeman

...

2020/2

The fundamental equations of change in statistical ensembles and biological populations

Entropy

Steven A Frank

Frank J Bruggeman

2020/12/10

See List of Professors in Frank J Bruggeman University(Vrije Universiteit Amsterdam)

Co-Authors

H-index: 97
Hans Westerhoff

Hans Westerhoff

Manchester University

H-index: 68
Jan B. Hoek

Jan B. Hoek

Thomas Jefferson University

H-index: 64
Boris Kholodenko

Boris Kholodenko

University College Dublin

H-index: 64
Bas Teusink

Bas Teusink

Vrije Universiteit Amsterdam

H-index: 53
Barbara Bakker

Barbara Bakker

Rijksuniversiteit Groningen

H-index: 51
Wilfred F.M. Roling

Wilfred F.M. Roling

Vrije Universiteit Amsterdam

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