Fabrizio Chiti
Università degli Studi di Firenze
H-index: 68
Europe-Italy
Top articles of Fabrizio Chiti
Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases
2024/12
Fabrizio Chiti
H-Index: 38
Michele Vendruscolo
H-Index: 70
Structure–Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates
Journal of the American Chemical Society
2024/4/3
Cristina Cecchi
H-Index: 24
Fabrizio Chiti
H-Index: 38
Giuliana Fusco
H-Index: 12
Alfonso De Simone
H-Index: 27
Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
Translational Neurodegeneration
2024/3/8
Lorenzo Neri
H-Index: 1
Sandro Sorbi
H-Index: 59
Benedetta Nacmias
H-Index: 43
Cristina Cecchi
H-Index: 24
Fabrizio Chiti
H-Index: 38
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
Alzheimer's Research & Therapy
2024/1/18
Leveraging Machine Learning-Guided Molecular Simulations Coupled with Experimental Data to Decipher Membrane Binding Mechanisms of Aminosterols
bioRxiv
2024
Fabrizio Chiti
H-Index: 38
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature
Annals of Medicine
2023/12/31
Single domain antibodies as promising tools for the selective detection and neutralization of neurotoxic Aβ42 oligomers in the cerebrospinal fluid of Alzheimer’s …
Alzheimer's & Dementia
2023/12
Fabrizio Chiti
H-Index: 38
Cristina Cecchi
H-Index: 24
Amyloid Aggregation Is Potently Slowed Down by Osmolytes Due to Compaction of Partially Folded State
Journal of Molecular Biology
2023/11/15
Daniel Harries
H-Index: 26
Fabrizio Chiti
H-Index: 38
Alzheimer Disease Detection from Raman Spectroscopy of the Cerebrospinal Fluid via Topological Machine Learning
Engineering Proceedings
2023/10/27
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes
Journal of Medicinal Chemistry
2023/7/11
Single domain antibodies as new detectors of neurotoxic Aβ42 oligomers
Alzheimer's & Dementia
2023/6
Fabrizio Chiti
H-Index: 38
Cristina Cecchi
H-Index: 24
Characterization of pairs of toxic and nontoxic misfolded protein oligomers elucidates the structural determinants of oligomer toxicity in protein misfolding diseases
2023/4/18
Michele Vendruscolo
H-Index: 70
Fabrizio Chiti
H-Index: 38
Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol
Colloids and Surfaces B: Biointerfaces
2023/2/1
Fabrizio Chiti
H-Index: 38
Gabriella Caminati
H-Index: 13
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity
Chemico-Biological Interactions
2023/2/1
Fabrizio Chiti
H-Index: 38
Michele Vendruscolo
H-Index: 70
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Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors
The FEBS Journal
2023/1
Caterina Bernacchioni
H-Index: 16
Paola Bruni
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Fabrizio Chiti
H-Index: 38
Cristina Cecchi
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Biophysical characterization of full‐length TAR DNA‐binding protein (TDP‐43) phase separation
Protein Science
2022/12
Cristina Cecchi
H-Index: 24
Fabrizio Chiti
H-Index: 38
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases
2022/11
Fabrizio Chiti
H-Index: 38
Cristina Cecchi
H-Index: 24
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes
Frontiers in Molecular Biosciences
2022/9/7
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species
Cellular and Molecular Life Sciences
2022/9