Fabrizio Chiti
Università degli Studi di Firenze
H-index: 68
Europe-Italy
Top articles of Fabrizio Chiti
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Leveraging Machine Learning-Guided Molecular Simulations Coupled with Experimental Data to Decipher Membrane Binding Mechanisms of Aminosterols | bioRxiv | Stefano Muscat Silvia Errico Andrea Danani Fabrizio Chiti Gianvito Grasso | 2024 |
Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases | Dillon J Rinauro Fabrizio Chiti Michele Vendruscolo Ryan Limbocker | 2024/12 | |
Structure–Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates | Journal of the American Chemical Society | Serene W Chen Joseph D Barritt Roberta Cascella Alessandra Bigi Cristina Cecchi | 2024/4/3 |
Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort | Translational Neurodegeneration | Alessandra Bigi Giulia Fani Valentina Bessi Liliana Napolitano Silvia Bagnoli | 2024/3/8 |
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF | Alzheimer's Research & Therapy | Alessandra Bigi Liliana Napolitano Devkee M Vadukul Fabrizio Chiti Cristina Cecchi | 2024/1/18 |
Suggested searches | Perspective | Sunkyung Kim Jing Chen Feiya Ou Tian-Tian Liu Suin Jo | 2024/3/4 |
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes | Journal of Medicinal Chemistry | Silvia Errico Giacomo Lucchesi Davide Odino Enass Youssef Osman Roberta Cascella | 2023/7/11 |
Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors | The FEBS Journal | Alessandra Bigi Roberta Cascella Giulia Fani Caterina Bernacchioni Francesca Cencetti | 2023/1 |
Single domain antibodies as new detectors of neurotoxic Aβ42 oligomers | Alzheimer's & Dementia | Liliana Napolitano Alessandra Bigi Devkee Vadukul Francesco Aprile Fabrizio Chiti | 2023/6 |
An in situ and in vitro investigation of cytoplasmic TDP-43 inclusions reveals the absence of a clear amyloid signature | Annals of Medicine | Roberta Cascella Martina Banchelli Seyyed Abolghasem Ghadami Diletta Ami Maria Cristina Gagliani | 2023/12/31 |
Characterization of pairs of toxic and nontoxic misfolded protein oligomers elucidates the structural determinants of oligomer toxicity in protein misfolding diseases | Ryan Limbocker Nunilo Cremades Roberta Cascella Peter M Tessier Michele Vendruscolo | 2023/4/18 | |
Single domain antibodies as promising tools for the selective detection and neutralization of neurotoxic Aβ42 oligomers in the cerebrospinal fluid of Alzheimer’s … | Alzheimer's & Dementia | Liliana Napolitano Alessandra Bigi Devkee Vadukul Francesco Aprile Fabrizio Chiti | 2023/12 |
Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol | Colloids and Surfaces B: Biointerfaces | Beatrice Barletti Giacomo Lucchesi Stefano Muscat Silvia Errico Denise Barbut | 2023/2/1 |
Amyloid Aggregation Is Potently Slowed Down by Osmolytes Due to Compaction of Partially Folded State | Journal of Molecular Biology | Tommaso Garfagnini Francesco Bemporad Daniel Harries Fabrizio Chiti Assaf Friedler | 2023/11/15 |
EGCG inactivates a pore-forming toxin by promoting its oligomerization and decreasing its solvent-exposed hydrophobicity | Chemico-Biological Interactions | Justus M Gabriel Thomas Tan Dillon J Rinauro Claire M Hsu Caleb J Buettner | 2023/2/1 |
Alzheimer Disease Detection from Raman Spectroscopy of the Cerebrospinal Fluid via Topological Machine Learning | Engineering Proceedings | Francesco Conti Martina Banchelli Valentina Bessi Cristina Cecchi Fabrizio Chiti | 2023/10/27 |
A brain-permeable aminosterol regulates cell membranes to mitigate the toxicity of diverse pore-forming agents | ACS Chemical Neuroscience | Ryan P Kreiser Aidan K Wright Liam R Sasser Dillon J Rinauro Justus M Gabriel | 2022/4/11 |
Amyloid fibrils act as a reservoir of soluble oligomers, the main culprits in protein deposition diseases | Alessandra Bigi Roberta Cascella Fabrizio Chiti Cristina Cecchi | 2022/11 | |
Conversion of the native N-terminal domain of TDP-43 into a monomeric alternative fold with lower aggregation propensity | Molecules | Matteo Moretti Isabella Marzi Cristina Cantarutti Mirella Vivoli Vega Walter Mandaliti | 2022/7/5 |
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes | Frontiers in Molecular Biosciences | Giuliana Fusco Francesco Bemporad Fabrizio Chiti Christopher M Dobson Alfonso De Simone | 2022/9/7 |
