Eric Shifrut

About Eric Shifrut

Eric Shifrut, With an exceptional h-index of 27 and a recent h-index of 26 (since 2020), a distinguished researcher at University of California, San Francisco, specializes in the field of T cell engineering, Immuno-oncology.

His recent articles reflect a diverse array of research interests and contributions to the field:

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells

Targeted replacement of endogenous t cell receptors

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

A functional map of HIV-host interactions in primary human T cells

Hypoxia is a dominant remodeler of the effector T cell surface proteome relative to activation and regulatory T cell suppression

Highly Parallel Discovery of Synthetic Knockin Sequences for Enhanced Cancer Immunotherapies

Eric Shifrut Information

University

Position

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Citations(all)

3820

Citations(since 2020)

3215

Cited By

1688

hIndex(all)

27

hIndex(since 2020)

26

i10Index(all)

28

i10Index(since 2020)

28

Email

University Profile Page

Google Scholar

Eric Shifrut Skills & Research Interests

T cell engineering

Immuno-oncology

Top articles of Eric Shifrut

TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells

Frontiers in Immunology

2024/2/29

Eric Shifrut
Eric Shifrut

H-Index: 19

Fabio Ciceri
Fabio Ciceri

H-Index: 29

Targeted replacement of endogenous t cell receptors

2023/10/5

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Cell

2023/9/14

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

Nature biotechnology

2023/4

Pooled knock-in screening and heterologous polypeptides co-expressed under the control of endogenous loci

2023/3/2

A functional map of HIV-host interactions in primary human T cells

Nature communications

2022/4/1

Hypoxia is a dominant remodeler of the effector T cell surface proteome relative to activation and regulatory T cell suppression

Molecular & Cellular Proteomics

2022/4/1

Eric Shifrut
Eric Shifrut

H-Index: 19

Alexander Marson
Alexander Marson

H-Index: 30

Highly Parallel Discovery of Synthetic Knockin Sequences for Enhanced Cancer Immunotherapies

Blood

2022/11/15

Memento: generalized differential expression analysis of single-cell RNA-seq with method of moments estimation and efficient resampling

bioRxiv

2022/11/10

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Cancer Cell

2022/7/11

Compositions and methods for modifying regulatory t cells

2021/11/4

Gene targets for t-cell-based immunotherapy

2021/10/14

Hypoxia is a dominant remodeler of the CD8+ T cell surface proteome relative to activation and regulatory T cell-mediated suppression

bioRxiv

2021/6/7

Eric Shifrut
Eric Shifrut

H-Index: 19

Alexander Marson
Alexander Marson

H-Index: 30

Efficient generation of isogenic primary human myeloid cells using CRISPR-Cas9 ribonucleoproteins

Cell reports

2021/5/11

XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment

Science advances

2021/4/21

Functional CRISPR dissection of gene networks controlling human regulatory T cell identity

Nature immunology

2020/11

substituição-alvo de receptores de células t endógenos

2020/10/6

Layilin augments integrin activation to promote antitumor immunity

Journal of Experimental Medicine

2020/9/7

See List of Professors in Eric Shifrut University(University of California, San Francisco)