Eric Gaucher
Georgia State University
H-index: 41
North America-United States
Top articles of Eric Gaucher
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Factor VIII proteins having ancestral sequences, expression vectors, and uses related thereto | 2024/2/13 | ||
Protein | Eric Gaucher Vanessa Cox | 2023/7/28 | |
Protection of catalytic cofactors by polypeptides as a driver for the emergence of primordial enzymes | Molecular Biology and Evolution | Luis I Gutierrez-Rus Gloria Gamiz-Arco Jose A Gavira Eric A Gaucher Valeria A Risso | 2023/6 |
Oral delivery of nanoparticles carrying ancestral uricase enzyme protects against hyperuricemia in knockout mice | Biomacromolecules | Lily Tran Soumen Das Liangjun Zhao M.G. Finn Eric A. Gaucher | 2023/4/26 |
Nucleic acids encoding clotting factor variants and their use | 2023/4/25 | ||
Genetics re-establish the utility of 2-methylhopanes as cyanobacterial biomarkers before 750 million years ago | Nature Ecology & Evolution | Yosuke Hoshino Benjamin J Nettersheim David A Gold Christian Hallmann Galina Vinnichenko | 2023/12 |
Phylogenetic articulation of uric acid evolution in mammals and how it informs a therapeutic uricase | Molecular Biology and Evolution | Ze Li Yosuke Hoshino Lily Tran Eric A Gaucher | 2022/1/1 |
Do thrifty genes exist? Revisiting uricase | Richard J Johnson Laura G Sánchez‐Lozada Takahiko Nakagawa Bernardo Rodriguez‐Iturbe Dean Tolan | 2022/10 | |
Molecular coevolution of coagulation factor VIII and von Willebrand factor | Blood Advances | Philip M Zakas Christopher W Coyle Anja Brehm Marion Bayer Barbara Solecka-Witulska | 2021/2/9 |
CRISPR-Cas9-mediated reactivation of the uricase pseudogene in human cells prevents acute hyperuricemia | Molecular Therapy-Nucleic Acids | Lais de Lima Balico Eric A Gaucher | 2021/9/3 |
Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase | Nature communications | Gloria Gamiz-Arco Luis I Gutierrez-Rus Valeria A Risso Beatriz Ibarra-Molero Yosuke Hoshino | 2021/1/15 |
Evolution of bacterial steroid biosynthesis and its impact on eukaryogenesis | Proceedings of the National Academy of Sciences | Yosuke Hoshino Eric A Gaucher | 2021/6/22 |
Combining ancestral reconstruction with folding-landscape simulations to engineer heterologous protein expression | Journal of Molecular Biology | Gloria Gamiz-Arco Valeria A Risso Eric A Gaucher Jose A Gavira Athi N Naganathan | 2021/12/3 |
Ancestral sequence reconstruction: from chemical paleogenetics to maximum likelihood algorithms and beyond | Journal of Molecular Evolution | Avery GA Selberg Eric A Gaucher David A Liberles | 2021/4 |
Brief report: The uricase mutation in humans increases our risk for cancer growth | Cancer & Metabolism | Mehdi A Fini Miguel A Lanaspa Eric A Gaucher Brian Boutwell Takahiko Nakagawa | 2021/12 |
Identification of coagulation factor IX variants with enhanced activity through ancestral sequence reconstruction | Blood Advances | Kristopher A Knight Christopher W Coyle Caelan E Radford Ernest T Parker Andrew Fedanov | 2021/9/14 |
Brief Report: An Evolutionary Basis to Cancer Growth | Mehdi Fini Eric Gaucher Brian Boutwell Takahiko Nakagawa Richard Wright | 2021/3/2 | |
2-METHYLHOPANES AS UNIQUE CYANOBACTERIAL BIOMARKERS BEFORE 1.2 BILLION YEARS AGO | Yosuke Hoshino Benjamin Nettersheim Christian Hallmann G Vinnichenko J Brocks | 2021/9/12 | |
Resurrected Ancestral TIM-Barrel Glycosidase Displays Heme Binding and Allosteric Modulation | Biophysical Journal | Luis I Gutierrez-Rus Gloria Gamiz-Arco Valeria A Risso Beatriz Ibarra-Molero Yosuke Hoshino | 2021/2/12 |
Development of Coagulation Factor VIII Transgenes That Confer Greater Potency to Gene Therapies for Hemophilia A Through Ancestral Sequence Reconstruction | Christopher Coyle Jasmine Anickat Alex Condra Luke Blackmon Philip M Zakas | 2020/4/28 |
