Edmund R.S. Kunji

Edmund R.S. Kunji

University of Cambridge

H-index: 59

Europe-United Kingdom

About Edmund R.S. Kunji

Edmund R.S. Kunji, With an exceptional h-index of 59 and a recent h-index of 35 (since 2020), a distinguished researcher at University of Cambridge, specializes in the field of Mitochondrial carriers, Mitochondrial diseases, Structural biology, Membrane proteins, Solute transport.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis

Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition

A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

Structural basis of purine nucleotide inhibition of human uncoupling protein 1

The concise guide to PHARMACOLOGY 2023/24: transporters

Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism

The free-living flagellate Paratrimastix pyriformis uses a distinct mitochondrial carrier to balance adenine nucleotide pools

Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle

Edmund R.S. Kunji Information

University

Position

Professor of Biophysics

Citations(all)

12239

Citations(since 2020)

5223

Cited By

9093

hIndex(all)

59

hIndex(since 2020)

35

i10Index(all)

100

i10Index(since 2020)

85

Email

University Profile Page

Google Scholar

Edmund R.S. Kunji Skills & Research Interests

Mitochondrial carriers

Mitochondrial diseases

Structural biology

Membrane proteins

Solute transport

Top articles of Edmund R.S. Kunji

Title

Journal

Author(s)

Publication Date

Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis

Scott A Jones

Jonathan J Ruprecht

Paul G Crichton

Edmund RS Kunji

2024/4/1

Fifty years of the mitochondrial pyruvate carrier: New insights into its structure, function, and inhibition

Acta physiologica (Oxford, England)

Sotiria Tavoulari

Maximilian Sichrovsky

Edmund RS Kunji

2023/6/27

A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

bioRxiv

Eva Pyrihová

Martin S King

Alannah C King

M Rey Toleco

Mark van der Giezen

...

2023/11/2

Structural basis of purine nucleotide inhibition of human uncoupling protein 1

Science Advances

Scott A Jones

Prerana Gogoi

Jonathan J Ruprecht

Martin S King

Yang Lee

...

2023/5/31

The concise guide to PHARMACOLOGY 2023/24: transporters

British journal of pharmacology

Stephen PH Alexander

Doriano Fabbro

Eamonn Kelly

Alistair A Mathie

John A Peters

...

2023/10

Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism

EMBO reports

Camila Cimadamore‐Werthein

Stephany Jaiquel Baron

Martin S King

Roger Springett

Edmund RS Kunji

2023/8/3

The free-living flagellate Paratrimastix pyriformis uses a distinct mitochondrial carrier to balance adenine nucleotide pools

Archives of Biochemistry and Biophysics

Justyna Zítek

Martin S King

Priscila Peña-Diaz

Eva Pyrihová

Alannah C King

...

2023/7/1

Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle

Nature Communications

Vasiliki Mavridou

Martin S King

Sotiria Tavoulari

Jonathan J Ruprecht

Shane M Palmer

...

2022/6/23

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Molecular metabolism

Sotiria Tavoulari

Tom JJ Schirris

Vasiliki Mavridou

Chancievan Thangaratnarajah

Martin S King

...

2022/6/1

TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia

Brain

Luis Carlos Tábara

Fatema Al-Salmi

Reza Maroofian

Amna Mohammed Al-Futaisi

Fathiya Al-Murshedi

...

2022/9/1

Activating ligands of Uncoupling protein 1 identified by rapid membrane protein thermostability shift analysis

Molecular metabolism

Riccardo Cavalieri

Marlou Klein Hazebroek

Camila A Cotrim

Yang Lee

Edmund RS Kunji

...

2022/8/1

Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency

Sotiria Tavoulari

Denis Lacabanne

Chancievan Thangaratnarajah

Edmund RS Kunji

2022/8/1

Characterization of drug-induced human mitochondrial ADP/ATP carrier inhibition

Theranostics

Stephany Jaiquel Baron

Martin S King

Edmund RS Kunji

Tom JJ Schirris

2021

Structure, substrate binding, and symmetry of the mitochondrial ADP/ATP carrier in its matrix-open state

Biophysical Journal

Joel José Montalvo-Acosta

Edmund RS Kunji

Jonathan J Ruprecht

François Dehez

Christophe Chipot

2021/12/7

Exome sequencing identifies a disease variant of the mitochondrial ATP‐Mg/Pi carrier SLC25A25 in two families with kidney stones

Molecular Genetics & Genomic Medicine

M Reza Jabalameli

Fiona M Fitzpatrick

Roberto Colombo

Sarah A Howles

Gary Leggatt

...

2021/12

Structural mechanism of transport of mitochondrial carriers

JJ Ruprecht

ERS Kunji

2021/6/20

Thermostability assays: A generic and versatile tool for studying the functional and structural properties of membrane proteins in detergents

Biophysics of Membrane Proteins: Methods and Protocols

Steven PD Harborne

Martin S King

Edmund RS Kunji

2020

A single cysteine residue in the translocation pathway of the mitosomal ADP/ATP carrier from Cryptosporidium parvum confers a broad nucleotide specificity

International Journal of Molecular Sciences

Martin S King

Sotiria Tavoulari

Vasiliki Mavridou

Alannah C King

John Mifsud

...

2020/1

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology

Physiology (Bethesda)

Edmund R S Kunji

Martin S King

Jonathan J Ruprecht

Chancievan Thangaratnarajah

2020/9/1

Expression and Purification of Membrane Proteins in Saccharomyces cerevisiae

Expression, Purification, and Structural Biology of Membrane Proteins

Martin S King

Edmund RS Kunji

2020

See List of Professors in Edmund R.S. Kunji University(University of Cambridge)

Co-Authors

academic-engine