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Edgar Otto, PhD

Edgar Otto, PhD

University of Michigan

H-index: 80

North America-United States

Contact Edgar Otto, PhD

About Edgar Otto, PhD

Edgar Otto, PhD, With an exceptional h-index of 80 and a recent h-index of 55 (since 2020), a distinguished researcher at University of Michigan, specializes in the field of Nephrology, Human Genetics.

His recent articles reflect a diverse array of research interests and contributions to the field:

WCN24-1387 Integration of Single Cell Data from Human and RNA-Seq Analysis from Rat to Identify Surrogate Drugs Mimicking the Effects of Metabolic Bariatric Surgery

Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project

Plasma Proteins associated with Chronic Histopathologic Lesions on Kidney Biopsy

Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury preventing transition to chronic kidney disease

Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury

An atlas of healthy and injured cell states and niches in the human kidney

Defining the molecular correlate of arteriolar hyalinosis in kidney disease progression by integration of single cell transcriptomic analysis and pathology scoring

WCN23-0471 THE ENHANCEMENT OF METALLOTHIONEIN BIND METAL PATHWAY WITH SGLT2 INHIBITORS IN KIDNEY PROXIMAL TUBULES OF ADOLESCENTS WITH TYPE 2 DIABETES USING SINGLE CELL RNA-SEQ DATA

Edgar Otto, PhD Information

University

Position

Associate Research Scientist Internal Medicine-Nephrology

Citations(all)

21720

Citations(since 2020)

7289

Cited By

17254

hIndex(all)

80

hIndex(since 2020)

55

i10Index(all)

141

i10Index(since 2020)

107

Email

University Profile Page

Google Scholar

Edgar Otto, PhD Skills & Research Interests

Nephrology

Human Genetics

Top articles of Edgar Otto, PhD

WCN24-1387 Integration of Single Cell Data from Human and RNA-Seq Analysis from Rat to Identify Surrogate Drugs Mimicking the Effects of Metabolic Bariatric Surgery

Kidney International Reports

2024/4/1

Fadhl Alakwaa
Fadhl Alakwaa

H-Index: 6

Laura Pyle
Laura Pyle

H-Index: 27

Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project

American Journal of Kidney Diseases

2024/3/1

Jonathan Himmelfarb
Jonathan Himmelfarb

H-Index: 59

Kun Zhang
Kun Zhang

H-Index: 13

Laurence Beck
Laurence Beck

H-Index: 24

Ashish Verma
Ashish Verma

H-Index: 11

Gearoid Mcmahon
Gearoid Mcmahon

H-Index: 16

William Bush
William Bush

H-Index: 30

Anant Madabhushi
Anant Madabhushi

H-Index: 58

Jane Nguyen
Jane Nguyen

H-Index: 2

Andrew Bomback
Andrew Bomback

H-Index: 34

Girish Nadkarni
Girish Nadkarni

H-Index: 45

Stephen Ward
Stephen Ward

H-Index: 20

Yuguang Xiong
Yuguang Xiong

H-Index: 4

Debora Lidia Gisch
Debora Lidia Gisch

H-Index: 2

James Williams
James Williams

H-Index: 2

Kenneth Dunn
Kenneth Dunn

H-Index: 25

William Bowen
William Bowen

H-Index: 15

Katy Borner
Katy Borner

H-Index: 38

Mohamed Atta
Mohamed Atta

H-Index: 9

Steven Menez
Steven Menez

H-Index: 8

Chirag Parikh
Chirag Parikh

H-Index: 68

Yumeng Wen
Yumeng Wen

H-Index: 9

Jennifer Sun
Jennifer Sun

H-Index: 5

Samir Parikh
Samir Parikh

H-Index: 39

Olga Troyanskaya
Olga Troyanskaya

H-Index: 45

Garry Nolan
Garry Nolan

H-Index: 64

Plasma Proteins associated with Chronic Histopathologic Lesions on Kidney Biopsy

Journal of the American Society of Nephrology

2024/2/6

Taesoo Kim
Taesoo Kim

H-Index: 37

Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury preventing transition to chronic kidney disease

Kidney International

2024/2/1

Integrated multiomics implicates dysregulation of ECM and cell adhesion pathways as drivers of severe COVID-associated kidney injury

medRxiv

2024

Nanditha Anandakrishnan
Nanditha Anandakrishnan

H-Index: 2

Tong Liu
Tong Liu

H-Index: 5

Sean Eddy
Sean Eddy

H-Index: 17

Pushkala Jayaraman
Pushkala Jayaraman

H-Index: 6

Aparna Saha
Aparna Saha

H-Index: 18

Qian Sun
Qian Sun

H-Index: 1

Yang Dai
Yang Dai

H-Index: 6

Huei Hsun Wen
Huei Hsun Wen

H-Index: 5

Jia Fu
Jia Fu

H-Index: 2

Lisa Miorin
Lisa Miorin

H-Index: 20

Girish Nadkarni
Girish Nadkarni

H-Index: 45

Hong Li
Hong Li

H-Index: 7

Weijia Zhang
Weijia Zhang

H-Index: 5

An atlas of healthy and injured cell states and niches in the human kidney

Nature

2023/7/20

Qiwen Hu
Qiwen Hu

H-Index: 12

Kian Kalhor
Kian Kalhor

H-Index: 2

Dinh Diep
Dinh Diep

H-Index: 14

Sean Eddy
Sean Eddy

H-Index: 17

Bo Zhang
Bo Zhang

H-Index: 8

Yan Wu
Yan Wu

H-Index: 2

Xin Wang
Xin Wang

H-Index: 6

Anitha Vijayan
Anitha Vijayan

H-Index: 21

Fei Chen
Fei Chen

H-Index: 15

Paul M Palevsky
Paul M Palevsky

H-Index: 41

Eric H Kim
Eric H Kim

H-Index: 18

Kun Zhang
Kun Zhang

H-Index: 13

Sanjay Jain
Sanjay Jain

H-Index: 13

Defining the molecular correlate of arteriolar hyalinosis in kidney disease progression by integration of single cell transcriptomic analysis and pathology scoring

medRxiv

2023/6/14

Paul M Palevsky
Paul M Palevsky

H-Index: 41

Charles E Alpers
Charles E Alpers

H-Index: 50

WCN23-0471 THE ENHANCEMENT OF METALLOTHIONEIN BIND METAL PATHWAY WITH SGLT2 INHIBITORS IN KIDNEY PROXIMAL TUBULES OF ADOLESCENTS WITH TYPE 2 DIABETES USING SINGLE CELL RNA-SEQ DATA

Kidney International Reports

2023/3/1

SGLT2 inhibitors mitigate kidney tubular metabolic and mTORC1 perturbations in youth-onset type 2 diabetes

The Journal of clinical investigation

2023/3/1

Sean Eddy
Sean Eddy

H-Index: 17

Laura Pyle
Laura Pyle

H-Index: 27

Subramaniam Pennathur
Subramaniam Pennathur

H-Index: 46

Ken Inoki
Ken Inoki

H-Index: 44

Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis

Kidney international

2023/3/1

Sean Eddy
Sean Eddy

H-Index: 17

Patrick H Nachman
Patrick H Nachman

H-Index: 36

Dwomoa Adu
Dwomoa Adu

H-Index: 28

Role of endogenous adenine in kidney failure and mortality with diabetes

medRxiv

2023

Kumar Sharma
Kumar Sharma

H-Index: 14

Jens Hansen
Jens Hansen

H-Index: 4

Leila Hejazi
Leila Hejazi

H-Index: 10

Loki Natarajan
Loki Natarajan

H-Index: 45

Jing Zhang
Jing Zhang

H-Index: 7

Brian Kwan
Brian Kwan

H-Index: 5

Jonathan Himmelfarb
Jonathan Himmelfarb

H-Index: 59

Ravi Iyengar
Ravi Iyengar

H-Index: 35

Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients

The Journal of Clinical Investigation

2023/10/16

Kumar Sharma
Kumar Sharma

H-Index: 14

Jens Hansen
Jens Hansen

H-Index: 4

Leila Hejazi
Leila Hejazi

H-Index: 10

Loki Natarajan
Loki Natarajan

H-Index: 45

Jing Zhang
Jing Zhang

H-Index: 7

Brian Kwan
Brian Kwan

H-Index: 5

Jonathan Himmelfarb
Jonathan Himmelfarb

H-Index: 59

Hiddo Lambers Heerspink
Hiddo Lambers Heerspink

H-Index: 64

Ravi Iyengar
Ravi Iyengar

H-Index: 35

Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes

Kidney International

2023/10/1

Laura Pyle
Laura Pyle

H-Index: 27

A reference tissue atlas for the human kidney

Science advances

2022/6/8

Jens Hansen
Jens Hansen

H-Index: 4

Samir Parikh
Samir Parikh

H-Index: 39

Miguel Rivera
Miguel Rivera

H-Index: 0

Yuguang Xiong
Yuguang Xiong

H-Index: 4

Kumar Sharma
Kumar Sharma

H-Index: 14

Kun Zhang
Kun Zhang

H-Index: 13

Jonathan Himmelfarb
Jonathan Himmelfarb

H-Index: 59

M Todd Valerius
M Todd Valerius

H-Index: 21

Sanjay Jain
Sanjay Jain

H-Index: 13

Ravi Iyengar
Ravi Iyengar

H-Index: 35

Integrated single-cell sequencing and histopathological analyses reveal diverse injury and repair responses in a participant with acute kidney injury: a clinical-molecular …

Kidney international

2022/6/1

Steven Menez
Steven Menez

H-Index: 8

Sanjay Jain
Sanjay Jain

H-Index: 13

Jane Nguyen
Jane Nguyen

H-Index: 2

Shweta Bansal
Shweta Bansal

H-Index: 25

Mark Williams
Mark Williams

H-Index: 24

Ravi Iyengar
Ravi Iyengar

H-Index: 35

Jens Hansen
Jens Hansen

H-Index: 4

Yuguang Xiong
Yuguang Xiong

H-Index: 4

Samir Parikh
Samir Parikh

H-Index: 39

Olga Troyanskaya
Olga Troyanskaya

H-Index: 45

Kun Zhang
Kun Zhang

H-Index: 13

Garry Nolan
Garry Nolan

H-Index: 64

Minnie Sarwal
Minnie Sarwal

H-Index: 36

Sean Eddy
Sean Eddy

H-Index: 17

Paul M Palevsky
Paul M Palevsky

H-Index: 41

John A Kellum
John A Kellum

H-Index: 89

Raghavan Murugan
Raghavan Murugan

H-Index: 30

Charles E Alpers
Charles E Alpers

H-Index: 50

Jonathan Himmelfarb
Jonathan Himmelfarb

H-Index: 59

Adam Wilcox
Adam Wilcox

H-Index: 19

Kumar Sharma
Kumar Sharma

H-Index: 14

Miguel Vazquez
Miguel Vazquez

H-Index: 6

Glomerular endothelial cell-podocyte stresses and crosstalk in structurally normal kidney transplants

Kidney international

2022/4/1

Haniyeh Zamani
Haniyeh Zamani

H-Index: 1

Multi-scalar data integration links glomerular angiopoietin-tie signaling pathway activation with progression of diabetic kidney disease

Diabetes

2022/12/1

Jiahao Liu
Jiahao Liu

H-Index: 2

Subramaniam Pennathur
Subramaniam Pennathur

H-Index: 46

Min Chen
Min Chen

H-Index: 4

Urinary Transcriptomics Identified Inflammatory Signals Associated With COVID-19-Related AKI

Journal of the American Society of Nephrology

2022

N Singh
N Singh

H-Index: 18

SGLT2 inhibition mitigates perturbations in nephron segment-specific metabolic transcripts and mTOR pathway activity in kidneys of young persons with type 2 diabetes

MedRxiv

2022/7/24

Sean Eddy
Sean Eddy

H-Index: 17

Laura Pyle
Laura Pyle

H-Index: 27

PKD2 founder mutation is the most common mutation of polycystic kidney disease in Taiwan

NPJ Genomic Medicine

2022/7/1

Ming-Yen Lin
Ming-Yen Lin

H-Index: 9

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