Eddy Arnold

Eddy Arnold

Rutgers, The State University of New Jersey

H-index: 96

North America-United States

About Eddy Arnold

Eddy Arnold, With an exceptional h-index of 96 and a recent h-index of 38 (since 2020), a distinguished researcher at Rutgers, The State University of New Jersey, specializes in the field of structural biology, HIV/AIDS, influenza, infectious diseases, DNA and RNA polymerases.

His recent articles reflect a diverse array of research interests and contributions to the field:

Structures, functions and adaptations of the human LINE-1 ORF2 protein

Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Crystal structures of an HIV-1 reverse transcriptase second strand initiation complex with and without non-nucleoside inhibitors may explain slow nucleotide incorporation and …

Expanding our knowledge of the SARS-CoV-2 polyproteins: Structural and biochemical insights into the viral processing

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

Targeting HIV-1 Reverse transcriptase using a fragment-based approach

Eddy Arnold Information

University

Position

Board of Governors and Distinguished Professor of Chemistry and Chemical Biology

Citations(all)

32823

Citations(since 2020)

5211

Cited By

29271

hIndex(all)

96

hIndex(since 2020)

38

i10Index(all)

254

i10Index(since 2020)

133

Email

University Profile Page

Rutgers, The State University of New Jersey

Google Scholar

View Google Scholar Profile

Eddy Arnold Skills & Research Interests

structural biology

HIV/AIDS

influenza

infectious diseases

DNA and RNA polymerases

Top articles of Eddy Arnold

Title

Journal

Author(s)

Publication Date

Structures, functions and adaptations of the human LINE-1 ORF2 protein

Nature

Eric T Baldwin

Trevor van Eeuwen

David Hoyos

Arthur Zalevsky

Egor P Tchesnokov

...

2023/12/14

Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure

Proceedings of the National Academy of Sciences

Avik Biswas

Indrani Choudhuri

Eddy Arnold

Dmitry Lyumkis

Allan Haldane

...

2024/4/9

Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

Science

Bin Tan

Xiaoming Zhang

Ahmadullah Ansari

Prakash Jadhav

Haozhou Tan

...

2024/3/29

Crystal structures of an HIV-1 reverse transcriptase second strand initiation complex with and without non-nucleoside inhibitors may explain slow nucleotide incorporation and …

Biophysical Journal

Shawn Rumrill

Francesc X Ruiz

Eddy Arnold

2024/2/8

Expanding our knowledge of the SARS-CoV-2 polyproteins: Structural and biochemical insights into the viral processing

Biophysical Journal

Ruchi Yadav

Valentine V Courouble

Sanjay K Dey

Jerry Joe EK Harrison

Jennifer Timm

...

2024/2/8

Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

Communications Chemistry

Xiangyi Jiang

Boshi Huang

Shawn Rumrill

David Pople

Waleed A Zalloum

...

2023/4/29

Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening

Journal of Medicinal Chemistry

Ashima Chopra

Joseph D Bauman

Francesc X Ruiz

Eddy Arnold

2023/4/28

Targeting HIV-1 Reverse transcriptase using a fragment-based approach

Molecules

Mahta Mansouri

Shawn Rumrill

Shane Dawson

Adam Johnson

Jo-Anne Pinson

...

2023/3/30

Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model (preprint)

Science

Bin Tan

Xiaoming Zhang

Ahmadullah Ansari

Prakash Jadhav

Haozhou Tan

...

2024/3/29

Evolution of the SARS‐CoV‐2 proteome in three dimensions (3D) during the first 6 months of the COVID‐19 pandemic

Proteins: Structure, Function, and Bioinformatics

Joseph H Lubin

Christine Zardecki

Elliott M Dolan

Changpeng Lu

Zhuofan Shen

...

2022/5

Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro

Science Advances

Ruchi Yadav

Valentine V Courouble

Sanjay K Dey

Jerry Joe EK Harrison

Jennifer Timm

...

2022/12/9

Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine

Proceedings of the National Academy of Sciences

Abhimanyu K Singh

Brent De Wijngaert

Marc Bijnens

Kris Uyttersprot

Hoai Nguyen

...

2022/7/26

Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

Science Advances

Jerry Joe EK Harrison

Dario Oliveira Passos

Jessica F Bruhn

Joseph D Bauman

Lynda Tuberty

...

2022/7/6

Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific …

Proceedings of the National Academy of Sciences

Eric T Baldwin

Matthias Götte

Egor P Tchesnokov

Eddy Arnold

Margit Hagel

...

2022/7/5

Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing

Francesc X Ruiz

Anthony Hoang

Christopher R Dilmore

Jeffrey J DeStefano

Eddy Arnold

2022/2/23

2, 4, 5-trisubstituted pyrimidines as potent HIV-1 NNRTIs: rational design, synthesis, activity evaluation, and crystallographic studies

Journal of Medicinal Chemistry

Dongwei Kang

Francesc X Ruiz

Yanying Sun

Da Feng

Lanlan Jing

...

2021/3/18

Resolving the dynamic motions of SARS-CoV-2 nsp7 and nsp8 proteins using structural proteomics

bioRxiv

Valentine V Courouble

Sanjay Kumar Dey

Ruchi Yadav

Jennifer Timm

Jerry Joe EK Harrison

...

2021/3/6

HIV-1 gp120 antagonists also inhibit HIV-1 reverse transcriptase by bridging the NNRTI and NRTI sites

Journal of Medicinal Chemistry

Natalie Losada

Francesc X Ruiz

Francesca Curreli

Kevin Gruber

Alyssa Pilch

...

2021/11/4

Crystal structure of a retroviral polyprotein: Prototype foamy virus protease-reverse transcriptase (PR-RT)

bioRxiv

Jerry Joe EK Harrison

Steve Tuske

Kalyan Das

Francesc Xavier Ruiz

Joseph D Bauman

...

2021/1/1

Revealing the structural plasticity of SARS-CoV-2 nsp7 and nsp8 using structural proteomics

Journal of the American Society for Mass Spectrometry

Valentine V Courouble

Sanjay Kumar Dey

Ruchi Yadav

Jennifer Timm

Jerry Joe EK Harrison

...

2021/6/14

See List of Professors in Eddy Arnold University(Rutgers, The State University of New Jersey)

Co-Authors

H-index: 145
Jon Clardy

Jon Clardy

Harvard University

H-index: 88
Richard H. Ebright

Richard H. Ebright

Rutgers, The State University of New Jersey

H-index: 60
Kalyan Das

Kalyan Das

Katholieke Universiteit Leuven

H-index: 32
Martin S Taylor

Martin S Taylor

Harvard University

H-index: 22
Joseph D. Bauman

Joseph D. Bauman

Rutgers, The State University of New Jersey

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