Eddy Arnold
Rutgers, The State University of New Jersey
H-index: 96
North America-United States
Top articles of Eddy Arnold
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Structures, functions and adaptations of the human LINE-1 ORF2 protein | Nature | Eric T Baldwin Trevor van Eeuwen David Hoyos Arthur Zalevsky Egor P Tchesnokov | 2023/12/14 |
Kinetic coevolutionary models predict the temporal emergence of HIV-1 resistance mutations under drug selection pressure | Proceedings of the National Academy of Sciences | Avik Biswas Indrani Choudhuri Eddy Arnold Dmitry Lyumkis Allan Haldane | 2024/4/9 |
Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model | Science | Bin Tan Xiaoming Zhang Ahmadullah Ansari Prakash Jadhav Haozhou Tan | 2024/3/29 |
Crystal structures of an HIV-1 reverse transcriptase second strand initiation complex with and without non-nucleoside inhibitors may explain slow nucleotide incorporation and … | Biophysical Journal | Shawn Rumrill Francesc X Ruiz Eddy Arnold | 2024/2/8 |
Expanding our knowledge of the SARS-CoV-2 polyproteins: Structural and biochemical insights into the viral processing | Biophysical Journal | Ruchi Yadav Valentine V Courouble Sanjay K Dey Jerry Joe EK Harrison Jennifer Timm | 2024/2/8 |
Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors | Communications Chemistry | Xiangyi Jiang Boshi Huang Shawn Rumrill David Pople Waleed A Zalloum | 2023/4/29 |
Halo Library, a Tool for Rapid Identification of Ligand Binding Sites on Proteins Using Crystallographic Fragment Screening | Journal of Medicinal Chemistry | Ashima Chopra Joseph D Bauman Francesc X Ruiz Eddy Arnold | 2023/4/28 |
Targeting HIV-1 Reverse transcriptase using a fragment-based approach | Molecules | Mahta Mansouri Shawn Rumrill Shane Dawson Adam Johnson Jo-Anne Pinson | 2023/3/30 |
Design of SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model (preprint) | Science | Bin Tan Xiaoming Zhang Ahmadullah Ansari Prakash Jadhav Haozhou Tan | 2024/3/29 |
Evolution of the SARS‐CoV‐2 proteome in three dimensions (3D) during the first 6 months of the COVID‐19 pandemic | Proteins: Structure, Function, and Bioinformatics | Joseph H Lubin Christine Zardecki Elliott M Dolan Changpeng Lu Zhuofan Shen | 2022/5 |
Biochemical and structural insights into SARS-CoV-2 polyprotein processing by Mpro | Science Advances | Ruchi Yadav Valentine V Courouble Sanjay K Dey Jerry Joe EK Harrison Jennifer Timm | 2022/12/9 |
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine | Proceedings of the National Academy of Sciences | Abhimanyu K Singh Brent De Wijngaert Marc Bijnens Kris Uyttersprot Hoai Nguyen | 2022/7/26 |
Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation | Science Advances | Jerry Joe EK Harrison Dario Oliveira Passos Jessica F Bruhn Joseph D Bauman Lynda Tuberty | 2022/7/6 |
Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K–specific … | Proceedings of the National Academy of Sciences | Eric T Baldwin Matthias Götte Egor P Tchesnokov Eddy Arnold Margit Hagel | 2022/7/5 |
Structural basis of HIV inhibition by L-nucleosides: Opportunities for drug development and repurposing | Francesc X Ruiz Anthony Hoang Christopher R Dilmore Jeffrey J DeStefano Eddy Arnold | 2022/2/23 | |
2, 4, 5-trisubstituted pyrimidines as potent HIV-1 NNRTIs: rational design, synthesis, activity evaluation, and crystallographic studies | Journal of Medicinal Chemistry | Dongwei Kang Francesc X Ruiz Yanying Sun Da Feng Lanlan Jing | 2021/3/18 |
Resolving the dynamic motions of SARS-CoV-2 nsp7 and nsp8 proteins using structural proteomics | bioRxiv | Valentine V Courouble Sanjay Kumar Dey Ruchi Yadav Jennifer Timm Jerry Joe EK Harrison | 2021/3/6 |
HIV-1 gp120 antagonists also inhibit HIV-1 reverse transcriptase by bridging the NNRTI and NRTI sites | Journal of Medicinal Chemistry | Natalie Losada Francesc X Ruiz Francesca Curreli Kevin Gruber Alyssa Pilch | 2021/11/4 |
Crystal structure of a retroviral polyprotein: Prototype foamy virus protease-reverse transcriptase (PR-RT) | bioRxiv | Jerry Joe EK Harrison Steve Tuske Kalyan Das Francesc Xavier Ruiz Joseph D Bauman | 2021/1/1 |
Revealing the structural plasticity of SARS-CoV-2 nsp7 and nsp8 using structural proteomics | Journal of the American Society for Mass Spectrometry | Valentine V Courouble Sanjay Kumar Dey Ruchi Yadav Jennifer Timm Jerry Joe EK Harrison | 2021/6/14 |