Dr. Kakularam Kumar Reddy

About Dr. Kakularam Kumar Reddy

Dr. Kakularam Kumar Reddy, With an exceptional h-index of 11 and a recent h-index of 9 (since 2020), a distinguished researcher at University of Hyderabad, specializes in the field of Bioinformatics, Protein Biology.

His recent articles reflect a diverse array of research interests and contributions to the field:

Speculating on the Evolutionary Pathway of the Hypothalamus-Pituitary-Thyroid Axis

Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities

Functional Characterization of transgenic mice overexpressing human 15-Lipoxygenase-1 (ALOX15) under the control of the aP2 promoter

Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate …

Male knock-in mice expressing an arachidonic acid lipoxygenase 15B (Alox15B) with humanized reaction specificity are prematurely growth arrested when aging

The reaction specificity of mammalian ALOX15 orthologs is changed during late primate evolution and these alterations might offer evolutionary advantages for hominidae

Dr. Kakularam Kumar Reddy Information

University

Position

___

Citations(all)

648

Citations(since 2020)

379

Cited By

393

hIndex(all)

11

hIndex(since 2020)

9

i10Index(all)

11

i10Index(since 2020)

9

Email

University Profile Page

Google Scholar

Dr. Kakularam Kumar Reddy Skills & Research Interests

Bioinformatics

Protein Biology

Top articles of Dr. Kakularam Kumar Reddy

Title

Journal

Author(s)

Publication Date

Speculating on the Evolutionary Pathway of the Hypothalamus-Pituitary-Thyroid Axis

Claudia Ricci

Kumar Reddy Kakularam

Carlotta Marzocchi

Anna Cantore

Hartmut Kuhn

...

2024/4/1

Design, synthesis and evaluation of 2-aryl quinoline derivatives against 12R-lipoxygenase (12R-LOX): Discovery of first inhibitor of 12R-LOX

Bioorganic Chemistry

Harshavardhan Bhuktar

Sharda Shukla

Kumar Reddy Kakularam

Srikanth Battu

Manupati Srikanth

...

2023/9/1

Transgenic mice overexpressing human ALOX15 under the control of the aP2 promoter are partly protected in the complete Freund’s adjuvant-induced paw inflammation model

Inflammation Research

Dagmar Heydeck

Kumar R Kakularam

Dominika Labuz

Halina Machelska

Nadine Rohwer

...

2023/8

Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities

International journal of molecular sciences

Kumar R Kakularam

Miquel Canyelles-Niño

Xin Chen

José M Lluch

Àngels González-Lafont

...

2023/6/12

Functional Characterization of transgenic mice overexpressing human 15-Lipoxygenase-1 (ALOX15) under the control of the aP2 promoter

International journal of molecular sciences

Dagmar Heydeck

Christoph Ufer

Kumar R Kakularam

Michael Rothe

Thomas Liehr

...

2023/3/2

Bony Fish Arachidonic Acid 15-Lipoxygenases Exhibit Different Catalytic Properties than Their Mammalian Orthologs, Suggesting Functional Enzyme Evolution during Vertebrate …

International Journal of Molecular Sciences

Sophie Roigas

Kumar R Kakularam

Michael Rothe

Dagmar Heydeck

Polamarasetty Aparoy

...

2023/9/15

Male knock-in mice expressing an arachidonic acid lipoxygenase 15B (Alox15B) with humanized reaction specificity are prematurely growth arrested when aging

Biomedicines

Marjann Schäfer

Kumar R Kakularam

Florian Reisch

Michael Rothe

Sabine Stehling

...

2022/6/10

The reaction specificity of mammalian ALOX15 orthologs is changed during late primate evolution and these alterations might offer evolutionary advantages for hominidae

Frontiers in cell and developmental biology

Dagmar Heydeck

Florian Reisch

Marjann Schäfer

Kumar R Kakularam

Sophie A Roigas

...

2022/4/21

N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs …

Journal of medicinal chemistry

Alexey Golovanov

Alexander Zhuravlev

Alejandro Cruz

Vladislav Aksenov

Rania Shafiullina

...

2022/1/25

Paralog-and ortholog-specificity of inhibitors of human and mouse lipoxygenase-isoforms

Biomedicine & Pharmacotherapy

Kumar Reddy Kakularam

Felix Karst

Aparoy Polamarasetty

Igor Ivanov

Dagmar Heydeck

...

2022/1/1

Heterocyclic Compounds as Lipoxygenase Inhibitors

2022/11/10

Eicosanoid biosynthesis in marine mammals

The FEBS journal

Florian Reisch

Kumar Reddy Kakularam

Sabine Stehling

Dagmar Heydeck

Hartmut Kuhn

2021/2

Oxygenation of endocannabinoids by mammalian lipoxygenase isoforms

Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

Igor Ivanov

Kumar R Kakularam

Elena V Shmendel

Michael Rothe

Polamarasetty Aparoy

...

2021/6/1

Thr92Ala polymorphism in the type 2 deiodinase gene: an evolutionary perspective

Journal of Endocrinological Investigation

C Ricci

KR Kakularam

C Marzocchi

G Capecchi

G Riolo

...

2020/12

Performance evaluation of docking programs-glide, gold, AutoDock & SurflexDock, using free energy perturbation reference data: a case study of fructose-1, 6-bisphosphatase-AMP …

K Kumar Reddy

RS Rathore

P Srujana

RR Burri

C Ravikumar Reddy

...

2020/7/1

Studies towards the Total Synthesis of Kadcotrione B

Synthesis

Julakanti Satyanarayana Reddy

Marri Gangababu

Patel Manimala

Aluru Rammohan

Jillu Singh Yadav

2020/3

See List of Professors in Dr. Kakularam Kumar Reddy University(University of Hyderabad)