douglas R higgs
University of Oxford
H-index: 112
Europe-United Kingdom
Top articles of douglas R higgs
Title | Journal | Author(s) | Publication Date |
---|---|---|---|
Sir David John Weatherall. 9 March 1933—8 December 2018 | BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY | Douglas R Higgs | 2023/11/29 |
Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future | Blood Journal | Ali Amid Siyu Liu Christian Babbs Douglas R Higgs | 2024/3/8 |
Beginnings: the molecular pathology of hemoglobin | Molecular Hematology | Douglas Higgs Mohsin Badat | 2024/5/28 |
The characteristics of CTCF binding sequences contribute to enhancer blocking activity | bioRxiv | Felice H Tsang Rosa J Stolper Muhammad Hanifi Lucy J Cornell Helena S Francis | 2023 |
Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α‐globin locus | Mira Kassouf Seren Ford Joseph Blayney Doug Higgs | 2023/10 | |
Ancient genomic linkage couples metabolism with erythroid development | bioRxiv | Alexandra E Preston Joe N Frost Mohsin Badat Megan Teh Andrew E Armitage | 2023/9/25 |
Super-enhancers include classical enhancers and facilitators to fully activate gene expression | Cell | Joseph W Blayney Helena Francis Alexandra Rampasekova Brendan Camellato Leslie Mitchell | 2023/12/21 |
Direct correction of haemoglobin E β-thalassaemia using base editors | Nature Communications | Mohsin Badat Ayesha Ejaz Peng Hua Siobhan Rice Weijiao Zhang | 2023/4/19 |
Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes | bioRxiv | Guanjue Xiang Xi He Belinda M Giardine Kathryn J Isaac Dylan J Taylor | 2023/11/21 |
Active regulatory elements recruit cohesin to establish cell-specific chromatin domains. | bioRxiv | Emily Georgiades Caroline L Harrold Nigel Roberts Mira Kassouf Simone G Riva | 2023 |
RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation | Developmental Cell | Danya J Martell Hope E Merens Alexis Caulier Claudia Fiorini Jacob C Ulirsch | 2023/10/23 |
Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation | bioRxiv | Rosa J Stolper Felice H Tsang Emily Georgiades Lars LP Hanssen Damien J Downes | 2023 |
The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin | Nature Communications | Julia Truch Damien J Downes Caroline Scott E Ravza Gür Jelena M Telenius | 2022/6/17 |
An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis | Blood | Alexandra E Preston Joe N Frost Mohsin Badat Andrew E Armitage Sarah Wideman | 2022/11/15 |
Editing of haemoglobin genes | 2022/2/3 | ||
On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation | Nature Communications | DM Jeziorska EAJ Tunnacliffe JM Brown H Ayyub J Sloane-Stanley | 2022/11/4 |
Scalable in vitro production of defined mouse erythroblasts | Plos one | Helena S Francis Caroline L Harold Robert A Beagrie Andrew J King Matthew E Gosden | 2022/1/7 |
Multipartite super-enhancers function in an orientation-dependent manner | BioRxiv | Mira T Kassouf Helena S Francis Matthew Gosden Maria C Suciu Damien J Downes | 2022/7/14 |
P104: base editing repairs the HbE mutation restoring the production of normal globin chains in severe HbE/β-thalassemia patient hematopoietic stem and erythroid cells | HemaSphere | M Badat P Hua S Mettananda C Fisher N Roy | 2022/1/1 |
Functional impairment of erythropoiesis in Congenital Dyserythropoietic Anaemia type I arises at the progenitor level | British Journal of Haematology | Caroline Scott Kerol Bartolovic Sally‐Ann Clark Dominic Waithe Quentin A Hill | 2022/7 |