douglas R higgs

douglas R higgs

University of Oxford

H-index: 112

Europe-United Kingdom

About douglas R higgs

douglas R higgs, With an exceptional h-index of 112 and a recent h-index of 56 (since 2020), a distinguished researcher at University of Oxford, specializes in the field of gene expression, erythropoiesis, human genetics.

His recent articles reflect a diverse array of research interests and contributions to the field:

Sir David John Weatherall. 9 March 1933—8 December 2018

Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future

Beginnings: the molecular pathology of hemoglobin

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α‐globin locus

Ancient genomic linkage couples metabolism with erythroid development

Super-enhancers include classical enhancers and facilitators to fully activate gene expression

Direct correction of haemoglobin E β-thalassaemia using base editors

douglas R higgs Information

University

Position

Professor of haematology

Citations(all)

44114

Citations(since 2020)

11439

Cited By

38647

hIndex(all)

112

hIndex(since 2020)

56

i10Index(all)

348

i10Index(since 2020)

171

Email

University Profile Page

University of Oxford

Google Scholar

View Google Scholar Profile

douglas R higgs Skills & Research Interests

gene expression

erythropoiesis

human genetics

Top articles of douglas R higgs

Title

Journal

Author(s)

Publication Date

Sir David John Weatherall. 9 March 1933—8 December 2018

BIOGRAPHICAL MEMOIRS OF FELLOWS OF THE ROYAL SOCIETY

Douglas R Higgs

2023/11/29

Haemoglobin Bart's Hydrops Fetalis: Charting the Past and Envisioning the Future

Blood Journal

Ali Amid

Siyu Liu

Christian Babbs

Douglas R Higgs

2024/3/8

Beginnings: the molecular pathology of hemoglobin

Molecular Hematology

Douglas Higgs

Mohsin Badat

2024/5/28

The characteristics of CTCF binding sequences contribute to enhancer blocking activity

bioRxiv

Felice H Tsang

Rosa J Stolper

Muhammad Hanifi

Lucy J Cornell

Helena S Francis

...

2023

Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α‐globin locus

Mira Kassouf

Seren Ford

Joseph Blayney

Doug Higgs

2023/10

Ancient genomic linkage couples metabolism with erythroid development

bioRxiv

Alexandra E Preston

Joe N Frost

Mohsin Badat

Megan Teh

Andrew E Armitage

...

2023/9/25

Super-enhancers include classical enhancers and facilitators to fully activate gene expression

Cell

Joseph W Blayney

Helena Francis

Alexandra Rampasekova

Brendan Camellato

Leslie Mitchell

...

2023/12/21

Direct correction of haemoglobin E β-thalassaemia using base editors

Nature Communications

Mohsin Badat

Ayesha Ejaz

Peng Hua

Siobhan Rice

Weijiao Zhang

...

2023/4/19

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

bioRxiv

Guanjue Xiang

Xi He

Belinda M Giardine

Kathryn J Isaac

Dylan J Taylor

...

2023/11/21

Active regulatory elements recruit cohesin to establish cell-specific chromatin domains.

bioRxiv

Emily Georgiades

Caroline L Harrold

Nigel Roberts

Mira Kassouf

Simone G Riva

...

2023

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation

Developmental Cell

Danya J Martell

Hope E Merens

Alexis Caulier

Claudia Fiorini

Jacob C Ulirsch

...

2023/10/23

Loop extrusion by cohesin plays a key role in enhancer-activated gene expression during differentiation

bioRxiv

Rosa J Stolper

Felice H Tsang

Emily Georgiades

Lars LP Hanssen

Damien J Downes

...

2023

The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin

Nature Communications

Julia Truch

Damien J Downes

Caroline Scott

E Ravza Gür

Jelena M Telenius

...

2022/6/17

An Ancient Transcriptional Hub Couples Developmentally Regulated Gene Expression with Metabolism during Erythropoiesis

Blood

Alexandra E Preston

Joe N Frost

Mohsin Badat

Andrew E Armitage

Sarah Wideman

...

2022/11/15

Editing of haemoglobin genes

2022/2/3

On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation

Nature Communications

DM Jeziorska

EAJ Tunnacliffe

JM Brown

H Ayyub

J Sloane-Stanley

...

2022/11/4

Scalable in vitro production of defined mouse erythroblasts

Plos one

Helena S Francis

Caroline L Harold

Robert A Beagrie

Andrew J King

Matthew E Gosden

...

2022/1/7

Multipartite super-enhancers function in an orientation-dependent manner

BioRxiv

Mira T Kassouf

Helena S Francis

Matthew Gosden

Maria C Suciu

Damien J Downes

...

2022/7/14

P104: base editing repairs the HbE mutation restoring the production of normal globin chains in severe HbE/β-thalassemia patient hematopoietic stem and erythroid cells

HemaSphere

M Badat

P Hua

S Mettananda

C Fisher

N Roy

...

2022/1/1

Functional impairment of erythropoiesis in Congenital Dyserythropoietic Anaemia type I arises at the progenitor level

British Journal of Haematology

Caroline Scott

Kerol Bartolovic

Sally‐Ann Clark

Dominic Waithe

Quentin A Hill

...

2022/7

See List of Professors in douglas R higgs University(University of Oxford)