Douglas H. Smith

Douglas H. Smith

University of Pennsylvania

H-index: 97

North America-United States

About Douglas H. Smith

Douglas H. Smith, With an exceptional h-index of 97 and a recent h-index of 56 (since 2020), a distinguished researcher at University of Pennsylvania, specializes in the field of Traumatic Brain Injury, Concussion, Neurorepair, Diffuse Axonal Injury.

His recent articles reflect a diverse array of research interests and contributions to the field:

Dose-Dependent Tranexamic Acid Blunting of Penumbral Leukocyte Mobilization and Blood–Brain Barrier Permeability Following Traumatic Brain Injury: An In Vivo Murine Study

Delayed tranexamic acid after traumatic brain injury impedes learning and memory: Early tranexamic acid is favorable but not in sham animals

Lower and higher volumes of physical exercise build up brain reserves against memory deficits triggered by a head injury in mice

Translating from mice to humans: using preclinical blood-based biomarkers for the prognosis and treatment of traumatic brain injury

EARLY POST-TRAUMATIC BRAIN INJURY TXA PREVENTS BLOOD BRAIN BARRIER HYPERPERMEABILITY AND SURROGATES OF NEUROCLINICAL RECOVERY

Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2

DELAYED TXA AFTER TBI IMPEDES LEARNING, MEMORY; EARLY TXA IS FAVORABLE BUT NOT IN SHAM ANIMALS

Early posttraumatic brain injury tranexamic acid prevents blood-brain barrier hyperpermeability and improves surrogates of neuroclinical recovery

Douglas H. Smith Information

University

Position

Prof. Neurosurgery Director - Center for Brain Injury and Repair

Citations(all)

34225

Citations(since 2020)

11313

Cited By

26675

hIndex(all)

97

hIndex(since 2020)

56

i10Index(all)

237

i10Index(since 2020)

163

Email

University Profile Page

University of Pennsylvania

Google Scholar

View Google Scholar Profile

Douglas H. Smith Skills & Research Interests

Traumatic Brain Injury

Concussion

Neurorepair

Diffuse Axonal Injury

Top articles of Douglas H. Smith

Title

Journal

Author(s)

Publication Date

Dose-Dependent Tranexamic Acid Blunting of Penumbral Leukocyte Mobilization and Blood–Brain Barrier Permeability Following Traumatic Brain Injury: An In Vivo Murine Study

Neurocritical Care

Matthew C Culkin

Priyanka Bele

Anastasia P Georges

Patricia Santos

Grace Niziolek

...

2024/3/5

Delayed tranexamic acid after traumatic brain injury impedes learning and memory: Early tranexamic acid is favorable but not in sham animals

Journal of Trauma and Acute Care Surgery

Matthew C Culkin

Michael Coons

Priyanka Bele

Advait Thaploo

Anastasia P Georges

...

2024/1/1

Lower and higher volumes of physical exercise build up brain reserves against memory deficits triggered by a head injury in mice

Experimental Neurology

Afonso Kopczynski

Randhall B Carteri

Marcelo S Rodolphi

Jean P Oses

Luiz O Portela

...

2023/5/1

Translating from mice to humans: using preclinical blood-based biomarkers for the prognosis and treatment of traumatic brain injury

bioRxiv

Ilaria Lisi

Federico Moro

Edoardo Mazzone

Niklas Marklund

Francesca Pischiutta

...

2023/12/4

EARLY POST-TRAUMATIC BRAIN INJURY TXA PREVENTS BLOOD BRAIN BARRIER HYPERPERMEABILITY AND SURROGATES OF NEUROCLINICAL RECOVERY

Journal of Trauma and Acute Care Surgery

Matthew C Culkin

Priyanka Bele

Anastasia P Georges

Alfonso J Lopez

Grace Niziolek

...

2023/4/11

Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2

Acta neuropathologica

Hailong Song

Alexandra Tomasevich

Kofi K Acheampong

Dylan L Schaff

Sydney M Shaffer

...

2023/11

DELAYED TXA AFTER TBI IMPEDES LEARNING, MEMORY; EARLY TXA IS FAVORABLE BUT NOT IN SHAM ANIMALS

Journal of Trauma and Acute Care Surgery

Matthew C Culkin

Michael Coons

Priyanka Bele

Advait Thaploo

Anastasia P Georges

...

2023/1/11

Early posttraumatic brain injury tranexamic acid prevents blood-brain barrier hyperpermeability and improves surrogates of neuroclinical recovery

Journal of Trauma and Acute Care Surgery

Matthew C Culkin

Priyanka Bele

Anastasia P Georges

Alfonso J Lopez

Grace Niziolek

...

2023/7/1

Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs–An exploratory study

Frontiers in Cellular Neuroscience

James P Harris

Constance J Mietus

Kevin D Browne

Kathryn L Wofford

Carolyn E Keating

...

2023

The perils of contact sport: pathologies of diffuse brain swelling and chronic traumatic encephalopathy neuropathologic change in a 23-year-old rugby union player

Acta Neuropathologica

Edward B Lee

Claire Kennedy-Dietrich

Jennian F Geddes

James AR Nicoll

Tamas Revesz

...

2023/6

Traumatic brain injury recapitulates developmental changes of axons

Progress in Neurobiology

Hailong Song

Chen Chen

Brian Kelley

Alexandra Tomasevich

Hyoungjoo Lee

...

2022/10/1

Genetic testing to inform epilepsy treatment management from an international study of clinical practice

JAMA neurology

Dianalee McKnight

Ana Morales

Kathryn E Hatchell

Sara L Bristow

Joshua L Bonkowsky

...

2022/12/1

Beta blockade in TBI: Dose-dependent reductions in BBB leukocyte mobilization and permeability in vivo

Journal of Trauma and Acute Care Surgery

Alfonso J Lopez

Mohamed ElSaadani

Christina L Jacovides

Anastasia Georges

Matthew C Culkin

...

2022/5/1

Persistent Blunting of Penumbral Leukocyte Mobilization by Beta Blockade Administered for Two Weeks After Traumatic Brain Injury

Journal of Surgical Research

Alfonso J Lopez

Mohamed ElSaadani

Matthew C Culkin

Christina L Jacovides

Anastasia P Georges

...

2022/12/1

Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change

Acta neuropathologica communications

Kamar E Ameen-Ali

Abigail Bretzin

Edward B Lee

Rebecca Folkerth

Lili-Naz Hazrati

...

2022/4/11

Non-linear device head coupling and temporal delays in large animal acceleration models of traumatic brain injury

Annals of Biomedical Engineering

Andrew R Mayer

Josef M Ling

Declan A Patton

David D Stephenson

Andrew B Dodd

...

2022/6

Using UAS-multispectral images to predict cord yield under different planting dates

ASA, CSSA, SSSA International Annual Meeting

BALA SAPKOTA

Sayantan Sarkar

Gurjinder S Baath

Kyle Flynn

Douglas Smith

2022/11/7

Tissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs

Science Advances

Douglas H Smith

Justin C Burrell

Kevin D Browne

Kritika S Katiyar

Mindy I Ezra

...

2022/11/4

Cerebrospinal fluid purinomics as a biomarker approach to predict outcome after severe traumatic brain injury

Journal of neurochemistry

Nathan R Strogulski

Marco Antonio Stefani

Ana Elisa Böhmer

Gisele Hansel

Marcelo S Rodolphi

...

2022/4

Ultrasensitive single extracellular vesicle detection using high throughput droplet digital enzyme-linked immunosorbent assay

Nano letters

Zijian Yang

Yasemin Atiyas

Hanfei Shen

Michael J Siedlik

Jingyu Wu

...

2022/5/19

See List of Professors in Douglas H. Smith University(University of Pennsylvania)

Co-Authors

H-index: 102
Max Wintermark, MD, MAS

Max Wintermark, MD, MAS

Stanford University

H-index: 99
David Alsop

David Alsop

Harvard University

H-index: 83
Pratik Mukherjee

Pratik Mukherjee

University of California, San Francisco

H-index: 73
David Meaney

David Meaney

University of Pennsylvania

H-index: 69
Peter K. Stys

Peter K. Stys

University of Calgary

H-index: 56
David L Brody

David L Brody

Washington University in St. Louis

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