Douglas A Mitchell

Douglas A Mitchell

University of Illinois at Urbana-Champaign

H-index: 52

North America-United States

About Douglas A Mitchell

Douglas A Mitchell, With an exceptional h-index of 52 and a recent h-index of 41 (since 2020), a distinguished researcher at University of Illinois at Urbana-Champaign, specializes in the field of chemical biology, natural product biosynthesis, genome-mining, RiPPs.

His recent articles reflect a diverse array of research interests and contributions to the field:

Non-modular fatty acid synthases yield distinct N-terminal acylation in ribosomal peptides

Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications

Substrate Prediction for RiPP Biosynthetic Enzymes via Masked Language Modeling and Transfer Learning

High-Yield Lasso Peptide Production in a Burkholderia Bacterial Host by Plasmid Copy Number Engineering

Discovery of Borosin Catalytic Strategies and Function through Bioinformatic Profiling

Computationally guided exploration of borosin biosynthetic strategies

Enterolyin S, a Polythiazole‐containing Hemolytic Peptide from Enterococcus caccae

Genome mining unveils a class of ribosomal peptides with two amino termini

Douglas A Mitchell Information

University

Position

Professor of Chemistry

Citations(all)

11634

Citations(since 2020)

7176

Cited By

7537

hIndex(all)

52

hIndex(since 2020)

41

i10Index(all)

87

i10Index(since 2020)

82

Email

University Profile Page

University of Illinois at Urbana-Champaign

Google Scholar

View Google Scholar Profile

Douglas A Mitchell Skills & Research Interests

chemical biology

natural product biosynthesis

genome-mining

RiPPs

Top articles of Douglas A Mitchell

Title

Journal

Author(s)

Publication Date

Non-modular fatty acid synthases yield distinct N-terminal acylation in ribosomal peptides

Nature Chemistry

Hengqian Ren

Chunshuai Huang

Yuwei Pan

Shravan R Dommaraju

Haiyang Cui

...

2024/3/25

Tryptophan-Centric Bioinformatics Identifies New Lasso Peptide Modifications

Biochemistry

Lonnie A Harris

Hamada Saad

Kyle E Shelton

Lingyang Zhu

Xiaorui Guo

...

2024/3/18

Substrate Prediction for RiPP Biosynthetic Enzymes via Masked Language Modeling and Transfer Learning

arXiv preprint arXiv:2402.15181

Joseph D Clark

Xuenan Mi

Douglas A Mitchell

Diwakar Shukla

2024/2/23

High-Yield Lasso Peptide Production in a Burkholderia Bacterial Host by Plasmid Copy Number Engineering

ACS Synthetic Biology

Hannah N Fernandez

Ashley M Kretsch

Sylvia Kunakom

Adjo E Kadjo

Douglas A Mitchell

...

2024/1/9

Discovery of Borosin Catalytic Strategies and Function through Bioinformatic Profiling

ACS Chemical Biology

Aileen R Lee

Riley S Carter

Aman S Imani

Shravan R Dommaraju

Graham A Hudson

...

2024/5/2

Computationally guided exploration of borosin biosynthetic strategies

bioRxiv

Aileen R Lee

Riley S Carter

Aman S Imani

Shravan R Dommaraju

Graham A Hudson

...

2024

Enterolyin S, a Polythiazole‐containing Hemolytic Peptide from Enterococcus caccae

ChemBioChem

Chengyou Shi

Varshal A Patel

Douglas A Mitchell

Huimin Zhao

2024/4/22

Genome mining unveils a class of ribosomal peptides with two amino termini

Nature Communications

Hengqian Ren

Shravan R Dommaraju

Chunshuai Huang

Haiyang Cui

Yuwei Pan

...

2023/3/23

Benzylic Radical Stabilization Permits Ether Formation During Darobactin Biosynthesis

bioRxiv

Austin M Woodard

Francesca Peccati

Claudio D Navo

Gonzalo Jiménez-Osés

Douglas A Mitchell

2023/11/29

Bioinformatic prediction and experimental validation of RiPP recognition elements

Immunotherapy

Maryam Keshtvarz

Jafar Salimian

Mehdi Yaseri

Seyedeh Zahra Bathaie

Ehsan Rezaie

...

2017/4

Bioinformatics-guided discovery of biaryl-tailored lasso peptides

bioRxiv

Hamada Saad

Thomas Majer

Keshab Bhattarai

Sarah Lampe

Dinh T Nguyen

...

2023/3/6

Discovery of biaryl macrocyclic peptides with C-terminal β-amino-α-keto acid groups.

Biorxiv: the Preprint Server for Biology

Dinh T Nguyen

Lingyang Zhu

Douglas A Mitchell

Wilfred A van der Donk

2023/11/7

Catalytic Site Proximity Profiling for Functional Unification of Sequence-Diverse Radical S-Adenosylmethionine Enzymes

ACS bio & med Chem Au

Timothy W Precord

Sangeetha Ramesh

Shravan R Dommaraju

Lonnie A Harris

Bryce L Kille

...

2023/3/1

Biosynthesis of macrocyclic peptides with C-terminal β-amino-α-keto acid groups by three different metalloenzymes

bioRxiv

Dinh T Nguyen

Lingyang Zhu

Danielle L Gray

Toby J Woods

Chandrashekhar Padhi

...

2023/10/30

Peptidase activation by a leader peptide-bound RiPP recognition element

Biochemistry

Ashley M Kretsch

Mayuresh G Gadgil

Adam J DiCaprio

Susanna E Barrett

Bryce L Kille

...

2023/2/3

Reverse-Engineered High-Yield Lasso Peptide Production in an Alternative Host

Hannah Fernandez

Ashley Kretsch

Sylvia Kunakom

Adjo Kadjo

Douglas Mitchell

...

2023/9/26

Bioinformatics-guided discovery of biaryl-linked lasso peptides

Chemical Science

Hamada Saad

Thomas Majer

Keshab Bhattarai

Sarah Lampe

Dinh T Nguyen

...

2023

McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly

Proceedings of the National Academy of Sciences

Grayson L Chadwick

Aaron MN Joiner

Sangeetha Ramesh

Douglas A Mitchell

Dipti D Nayak

2023/6/20

Non-modular Fatty Acid Synthases Yield Unique Acylation in Ribosomal Peptides

bioRxiv

Hengqian Ren

Chunshuai Huang

Yuwei Pan

Haiyang Cui

Shravan R Dommaraju

...

2023

Radical SAM Enzymes and the Unexplored Chemistry of RiPP Biosynthesis

The FASEB Journal

Douglas Mitchell

Timothy Precord

Graham Hudson

Nilkamal Mahanta

Brandon Burkhart

...

2022/5

See List of Professors in Douglas A Mitchell University(University of Illinois at Urbana-Champaign)

Co-Authors

H-index: 102
Michael A. MARLETTA

Michael A. MARLETTA

University of California, Berkeley

H-index: 93
Huimin Zhao

Huimin Zhao

University of Illinois at Urbana-Champaign

H-index: 64
William W. Metcalf

William W. Metcalf

University of Illinois at Urbana-Champaign

H-index: 55
Satish Nair

Satish Nair

University of Illinois at Urbana-Champaign

H-index: 21
Abhishek Sharma

Abhishek Sharma

Stevens Institute of Technology

H-index: 18
NILKAMAL MAHANTA

NILKAMAL MAHANTA

University of Illinois at Urbana-Champaign

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