Donald E. Spratt
Clark University
H-index: 19
North America-United States
Top articles of Donald E. Spratt
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Synthesis and evaluation of 2, 5-substituted pyrimidines as small-molecule gankyrin binders | Future Medicinal Chemistry | Dipti Kanabar Emma I Kane Tejashri Chavan Taylor M Laflamme Ethan Suarez | 2024/3 |
New Discoveries on Protein Recruitment and Regulation during the Early Stages of the DNA Damage Response Pathways | Kelly L Waters Donald E Spratt | 2024/1/30 | |
Optimization of Expression and Purification of the Antiviral Protein HERC5 for Structural Determination | Elnaz Yazdani Mahboobeh Nazari Abolghasem Esmaeili TEHRANI ARASH MINAI Rahman Emamzadeh | 2016 | |
Redefining the catalytic HECT domain boundaries for the HECT E3 ubiquitin ligase family | Bioscience reports | Emma I Kane Steven A Beasley Johanna M Schafer Justine E Bohl Young Sun Lee | 2022/10 |
Exchange broadening underlies the enhancement of IDE-dependent degradation of insulin by anionic membranes | ACS omega | Qiuchen Zheng Bethany Lee Micheal T Kebede Valerie A Ivancic Merc M Kemeh | 2022/7/7 |
Small-molecule Gankyrin inhibition as a therapeutic strategy for breast and lung cancer | Journal of medicinal chemistry | Dipti Kanabar Mimansa Goyal Emma I Kane Tejashri Chavan Abbas Kabir | 2022/6/27 |
Extending the Catalytic HECT Domain Boundaries for the HECT E3 Ubiquitin Ligase HACE1 Increases Solubility and Enzymatic Activity | The FASEB Journal | Emma I Kane Kayla Rich Steven Beasley Donald E Spratt | 2022/5 |
Intersection of redox chemistry and ubiquitylation: post-translational modifications required for maintaining cellular homeostasis and neuroprotection | Emma I Kane Kelly L Waters Donald E Spratt | 2021/8/18 | |
HERC5 and the ISGylation pathway: critical modulators of the antiviral immune response | Nicholas A Mathieu Ermela Paparisto Stephen D Barr Donald E Spratt | 2021/6/9 | |
Exploring the roles of HERC2 and the NEDD4L HECT E3 ubiquitin ligase subfamily in p53 signaling and the DNA damage response | Nicholas A Mathieu Rafael H Levin Donald E Spratt | 2021/3/31 | |
Structural insights into ankyrin repeat-containing proteins and their influence in ubiquitylation | Emma I Kane Donald E Spratt | 2021/1/9 | |
Differential effects of polyphenols on insulin proteolysis by the insulin-degrading enzyme | Antioxidants | Qiuchen Zheng Micheal T Kebede Bethany Lee Claire A Krasinski Saadman Islam | 2021/8/25 |
Structural and Mechanistic Characterization of HERC2 E3 Ubiquitin Ligase C‐lobe with Implications in Cancer, Prader‐Willi Syndrome, and Eye Color | The FASEB Journal | Kayla Rich Noah Schwaegerle Donald Spratt | 2020/4 |
Lysine 33 polyubiquitin chain formation by the HECT Ubiquitin E3 Ligase AREL1 | The FASEB Journal | Emily Rose Ladda Donald Spratt | 2020/4 |
HECT E3 ubiquitin ligases–emerging insights into their biological roles and disease relevance | Yaya Wang Diana Argiles-Castillo Emma I Kane Anning Zhou Donald E Spratt | 2020/4/1 | |
New discoveries on the roles of “other” HECT E3 ubiquitin ligases in disease development | Ubiquitin-Proteasome Pathway | Emma I Kane Donald E Spratt | 2020/3/21 |
An Angelman syndrome substitution in the HECT E3 ubiquitin ligase C-terminal Lobe of E6AP affects protein stability and activity | Plos one | Steven A Beasley Chloe E Kellum Rachel J Orlomoski Feston Idrizi Donald E Spratt | 2020/7/8 |
Crystal structure of the catalytic C‐lobe of the HECT‐type ubiquitin ligase E6AP | Protein Science | Lena K Ries Anna KL Liess Christian G Feiler Donald E Spratt Edward D Lowe | 2020/6 |
Co-Authors
