Dionicio Siegel

Dionicio Siegel

University of California, San Diego

H-index: 37

North America-United States

About Dionicio Siegel

Dionicio Siegel, With an exceptional h-index of 37 and a recent h-index of 27 (since 2020), a distinguished researcher at University of California, San Diego, specializes in the field of Synthetic organic chemsitry, medicinal chemistry, drug development.

His recent articles reflect a diverse array of research interests and contributions to the field:

Reverse metabolomics for the discovery of chemical structures from humans

Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry

Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells

The underappreciated diversity of bile acid modifications

Short synthesis of a broadly Reactive, cell permeable serine hydrolase Fluorophosphonate-Alkyne probe

A class of anti-inflammatory lipids decrease with aging in the central nervous system

Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice

Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line

Dionicio Siegel Information

University

Position

___

Citations(all)

4530

Citations(since 2020)

2514

Cited By

2857

hIndex(all)

37

hIndex(since 2020)

27

i10Index(all)

61

i10Index(since 2020)

53

Email

University Profile Page

University of California, San Diego

Google Scholar

View Google Scholar Profile

Dionicio Siegel Skills & Research Interests

Synthetic organic chemsitry

medicinal chemistry

drug development

Top articles of Dionicio Siegel

Title

Journal

Author(s)

Publication Date

Reverse metabolomics for the discovery of chemical structures from humans

Nature

Emily C Gentry

Stephanie L Collins

Morgan Panitchpakdi

Pedro Belda-Ferre

Allison K Stewart

...

2024/2/8

Tracking Inhibition of Human Small C-Terminal Domain Phosphatase 1 Using 193 nm Ultraviolet Photodissociation Mass Spectrometry

Journal of the American Society for Mass Spectrometry

Edwin E Escobar

Wanjie Yang

Michael B Lanzillotti

Kyle J Juetten

Samuel Shields

...

2024/4/25

Targeting of REST with rationally-designed small molecule compounds exhibits synergetic therapeutic potential in human glioblastoma cells

BMC biology

Svetlana B Panina

Joshua V Schweer

Qian Zhang

Gaurav Raina

Haley A Hardtke

...

2024/4/12

The underappreciated diversity of bile acid modifications

Cell

Ipsita Mohanty

Helena Mannochio-Russo

Joshua V Schweer

Yasin El Abiead

Wout Bittremieux

...

2024/3/28

Short synthesis of a broadly Reactive, cell permeable serine hydrolase Fluorophosphonate-Alkyne probe

Bioorganic & Medicinal Chemistry Letters

Srihari Konduri

Joshua Schweer

Dionicio Siegel

2023/10/15

A class of anti-inflammatory lipids decrease with aging in the central nervous system

Nature chemical biology

Dan Tan

Srihari Konduri

Meric Erikci Ertunc

Pan Zhang

Justin Wang

...

2023/2

Beneficial metabolic effects of PAHSAs depend on the gut microbiota in diet-induced obese mice

bioRxiv

Jennifer Lee

Kerry Wellenstein

Ali Rahnavard

Andrew Timothy Nelson

Marlena Holter

...

2023

Mechanistic insights gained from cell and molecular analysis of the neuroprotective potential of bioactive natural compounds in an immortalized hippocampal cell line

PloS one

Harris A Weisz

Deborah R Boone

William S Coggins

Gabrielle A Edwards

Hannah E Willey

...

2022/6/3

ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids

Nature

Rucha Patel

Anna Santoro

Peter Hofer

Dan Tan

Monika Oberer

...

2022/6/30

Synthesis of the 26-Membered Core of Thiopeptide Natural Products by Scalable Thiazole-Forming Reactions of Cysteine Derivatives and Nitriles

Synthesis

Trevor C Johnson

Mitchell P Christy

Dionicio Siegel

2021/2

Discovery of an IKK2 Site that Allosterically Controls Its Activation

bioRxiv

Sonjiala Jackson Hotchkiss

Maria Carmen Mulero

Garrett J Chan

Tapan Biswas

Smarajit Polley

...

2021/1/27

Synthesis of tetracyclines and analogues thereof

2021/12/7

Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)

Journal of Lipid Research

Pratik Aryal

Ismail Syed

Jennifer Lee

Rucha Patel

Andrew T Nelson

...

2021/1/1

A Synthesis-Based Reverse Metabolomics Approach for the Discovery of Chemical Structures from Humans and Animals.

Pieter Dorrestein

Emily Gentry

Stephanie Collins

Morgan Panitchpakdi

Pedro Belda-Ferre

...

2021/8/30

Compostos de tetraciclinas e análogos das mesmas, uso dos referidos compostos, composição farmacêutica, bem como métodos de sintetização e de preparação dos referidos compostos

2021/7/20

Vinaxanthone inhibits Semaphorin3A induced axonal growth cone collapse in embryonic neurons but fails to block its growth promoting effects on adult neurons

Scientific Reports

Evguenia Ivakhnitskaia

Matthew R Chin

Dionicio Siegel

Victor H Guaiquil

2021/6/21

Total synthesis of micrococcin P1 through scalable thiazole forming reactions of cysteine derivatives and nitriles

Organic letters

Mitchell P Christy

Trevor Johnson

Clare D McNerlin

John Woodard

Andrew T Nelson

...

2020/3/5

Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells

Blood Cells, Molecules, and Diseases

Jing Zhang

Xinxin Huang

Bin Guo

Scott Cooper

Maegan L Capitano

...

2020/9/1

1938-P: The Gut Microbiota Is Critical for the Beneficial Metabolic Effects of Palmitic Acid Hydroxy Stearic Acids (PAHSAs) in Diet-Induced Obese Mice

Diabetes

Jennifer Lee

Ali Rahnavard

Kerry Wellenstein

Andrew T Nelson

Clary B Clish

...

2020/6/1

1832-P: Palmitic Acid Esters of Hydroxy Stearic Acids Reduce Endogenous Glucose Production through GPR43 Activation

Diabetes

Anna Santoro

Peng Zhou

Yan Zhu

Odile D Peroni

Andrew T Nelson

...

2020/6/1

See List of Professors in Dionicio Siegel University(University of California, San Diego)