Derek Abbott

Derek Abbott

Case Western Reserve University

H-index: 41

North America-United States

About Derek Abbott

Derek Abbott, With an exceptional h-index of 41 and a recent h-index of 31 (since 2020), a distinguished researcher at Case Western Reserve University,

His recent articles reflect a diverse array of research interests and contributions to the field:

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis (vol 185, pg 283, 2022)

Chemical modulation of gasdermin D activity: Therapeutic implications and consequences

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface

Investigation of the Common Independent Component Analysis Approaches in Biological Signals for Removing Cardiac Field Artefact from EEG

Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis

Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies

TH17 cells promote CNS inflammation by sensing danger signals via Mincle

Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases

Derek Abbott Information

University

Position

___

Citations(all)

9577

Citations(since 2020)

4340

Cited By

6778

hIndex(all)

41

hIndex(since 2020)

31

i10Index(all)

58

i10Index(since 2020)

50

Email

University Profile Page

Case Western Reserve University

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Top articles of Derek Abbott

Title

Journal

Author(s)

Publication Date

GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis (vol 185, pg 283, 2022)

Cell

Nitish Rana

Giuseppe Privitera

Hannah C Kondolf

Katarzyna Bulek

Susana Lechuga

...

2022/1/20

Chemical modulation of gasdermin D activity: Therapeutic implications and consequences

Bowen Zhou

Derek W Abbott

2023/11/1

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface

Life Science Alliance

Mathilde Lethier

Karine Huard

Michael Hons

Adrien Favier

Bernhard Brutscher

...

2023/11/1

Investigation of the Common Independent Component Analysis Approaches in Biological Signals for Removing Cardiac Field Artefact from EEG

Maryam Ebrahimpour

Derek Abbott

Mathias Baumert

2023/7/24

Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis

Journal of Biological Chemistry

Hannah C Kondolf

AD Dana

George R Dubyak

Derek W Abbott

2023/2/1

Gasdermins and pannexin-1 mediate pathways of chemotherapy-induced cell lysis in hematopoietic malignancies

Science signaling

Bowen Zhou

Christopher B Ryder

George R Dubyak

Derek W Abbott

2022/12/20

TH17 cells promote CNS inflammation by sensing danger signals via Mincle

Nature communications

Quanri Zhang

Weiwei Liu

Han Wang

Hao Zhou

Katarzyna Bulek

...

2022/5/3

Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases

Cell reports

Bowen Zhou

Derek W Abbott

2021/4/13

Full-length gasdermin-B (GSDMB) regulates epithelial adhesion and migration, and is increased in patients with IBD

The Journal of Immunology

Nitish Rana

Rebecca Maywald

Hannah Kondolf

Derek W Abbott

Jason Heaney

...

2020/5/1

Discovery of a redox thiol switch: implications for cellular energy metabolism

Molecular & Cellular Proteomics

Xing-Huang Gao

Ling Li

Marc Parisien

Jing Wu

Ilya Bederman

...

2020/5/1

Human polymorphisms in GSDMD alter the inflammatory response

Journal of Biological Chemistry

Joseph K Rathkey

Tsan S Xiao

Derek W Abbott

2020/3/6

Caspase-1 engages full-length gasdermin D through two distinct interfaces that mediate caspase recruitment and substrate cleavage

Immunity

Zhonghua Liu

Chuanping Wang

Jie Yang

Yinghua Chen

Bowen Zhou

...

2020/6/17

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

Nature communications

Mausita Karmakar

Martin Minns

Elyse N Greenberg

Jose Diaz-Aponte

Kersi Pestonjamasp

...

2020/5/5

See List of Professors in Derek Abbott University(Case Western Reserve University)