Dennis Discher
University of Pennsylvania
H-index: 108
North America-United States
Top articles of Dennis Discher
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Genetic heterogeneity in p53-null leukemia increases transiently with spindle assembly checkpoint inhibition and is not rescued by p53 | Chromosoma | Mai Wang Steven Phan Brandon H Hayes Dennis E Discher | 2024/1 |
High interfacial tension of lipid droplets disrupts the nucleus, cytoskeleton, and motile functions | Biophysical Journal | Irena L Ivanovska Michael P Tobin Dennis E Discher | 2024/2/8 |
Cover Image, Volume 44, Issue 1 | Cancer Communications | Monika Raab Izabela Kostova Samuel Peña‐Llopis Daniela Fietz Monika Kressin | 2024/1 |
Intracellular enrichment of lipid droplets increases cytoskeletal polymerization and chromosome segregation errors | Biophysical Journal | Geng-Yuan Chen Lawrence J Dooling Megan Chung Dennis E Discher Michael A Lampson | 2024/2/8 |
Solid tumor cohesion and growth are overcome in phagocytosis by SIRPα-knockout macrophages | Biophysical Journal | Tristan Marchena Lawrence J Dooling Nicholas Ontko Jason C Andrechak Dennis E Discher | 2024/2/8 |
Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractile-strain-driven collagen degradation | Biophysical Journal | Karanvir Saini Sangkyun Cho Manu Tewari Abdelaziz Jalil Mai Wang | 2024/2/8 |
Chromosomal instability leads to durable tumor suppression upon macrophage-checkpoint disruption, with induction of anti-tumor IgG | Cancer Research | Dennis E Discher | 2024/3/22 |
Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects | bioRxiv | Serena Omo-Lamai Yufei Wang Manthan N Patel Eno-obong Essien Mengwen Shen | 2024 |
Macrophages aggregate and phase separate when activated via Fc receptors or inflammatory cytokines | Biophysical Journal | Lawrence J Dooling Nicholas Ontko Tristan Marchena Dennis E Discher | 2024/2/8 |
Confinement with Myosin-II suppression increases heritable loss of chromosomes, using live-cell ChReporters | BioRxiv | Brandon H Hayes Peter Kuangzheng Zhu Mai Wang Charlotte R Pfeifer Yuntao Xia | 2023/2/26 |
Titrating CD47 by mismatch CRISPR-interference reveals incomplete repression can eliminate IgG-opsonized tumors but limits induction of antitumor IgG | PNAS nexus | Brandon H Hayes Hui Zhu Jason C Andrechak Lawrence J Dooling Dennis E Discher | 2023/8 |
Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen | Biophysical Journal | Karanvir Saini Sangkyun Cho Manu Tewari Abdelaziz Jalil Mai Wang | 2023/2/10 |
Confinement plus myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters | Journal of cell science | Brandon H Hayes Peter Kuangzheng Zhu Mai Wang Charlotte R Pfeifer Yuntao Xia | 2023/6/1 |
Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture | Journal of Cell Biology | Irena L Ivanovska Michael P Tobin Tianyi Bai Lawrence J Dooling Dennis E Discher | 2023/5/22 |
Small fat droplets interact with structural filaments in macrophages with cytoskeletal dysfunction contributing to perturbed phagocytosis and migration | Biophysical Journal | Michael P Tobin Irena L Ivanovska Dennis E Discher | 2023/2/10 |
A Highlights from MBoC Selection: Differences in cell shape, motility, and growth reflect chromosomal number variations that can be visualized with live-cell ChReporters | Molecular Biology of the Cell | Michael P Tobin Charlotte R Pfeifer Peter Kuangzheng Zhu Brandon H Hayes Mai Wang | 2023/12/12 |
Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response | bioRxiv | Brandon H Hayes Mai Wang Hui Zhu Steven H Phan Jason C Andrechak | 2023/4/4 |
Differences in cell shape, motility, and growth reflect chromosomal number variations that can be visualized with live-cell ChReporters | Molecular Biology of the Cell | Michael P Tobin Charlotte R Pfeifer Peter Kuangzheng Zhu Brandon H Hayes Mai Wang | 2023/12/1 |
Fat-filled lipid droplets with high curvature act as stiff inclusions that disrupt the lamina, rupture the nucleus and increase DNA damage | Biophysical Journal | Irena L Ivanovska Michael P Tobin Lawrence J Dooling Dennis E Discher | 2023/2/10 |
Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses | Nature Biomedical Engineering | Lawrence J Dooling Jason C Andrechak Brandon H Hayes Siddhant Kadu William Zhang | 2023/9 |
Co-Authors
