Dean Paes
Universiteit Maastricht
H-index: 9
Europe-Netherlands
Top articles of Dean Paes
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Beta-amyloid associates directly with PDE4D5 to activate the enzyme and reduce cAMP availability | FEBS Letters | Yuan Yan Sin Ryan T Cameron Melissa Schepers Ruth MacLeod Tom A Wright | 2024/4/15 |
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | Brain, Behavior, and Immunity | Melissa Schepers Dean Paes Assia Tiane Ben Rombaut Elisabeth Piccart | 2023/3/1 |
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology | Cellular and Molecular Life Sciences | Dean Paes Melissa Schepers Emily Willems Ben Rombaut Assia Tiane | 2023/7 |
Picking the best isoform: PDE4D isoforms as therapeutic targets in Alzheimer’s disease | Dean Paes | 2023 | |
Soluble guanylate cyclase stimulator riociguat improves spatial memory in mice via peripheral mechanisms | Neuroscience Letters | Ellis Nelissen Britt TJ van Hagen Elentina K Argyrousi Nick P van Goethem Pim RA Heckman | 2022/9/25 |
Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types | Biophysical Journal | Dean Paes Sammy Hermans Daniel van den Hove Tim Vanmierlo Jos Prickaerts | 2022/7/19 |
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment | Molecular and cellular neuroscience | Britt TJ van Hagen Nick P van Goethem Ellis Nelissen Dean Paes Karin Koymans | 2022/5/1 |
Pharmacological inhibition of phosphodiesterase 7 enhances consolidation processes of spatial memory | Neurobiology of learning and memory | Susan McQuown Dean Paes Karsten Baumgärtel Jos Prickaerts Marco Peters | 2021/1/1 |
Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s disease | Neurobiology of Aging | Dean Paes Roy Lardenoije Riccardo M Carollo Janou AY Roubroeks Melissa Schepers | 2021/1/1 |
The molecular biology of phosphodiesterase 4 enzymes as pharmacological targets: an interplay of isoforms, conformational states, and inhibitors | Dean Paes Melissa Schepers Ben Rombaut Daniel van den Hove Tim Vanmierlo | 2021/7/1 | |
Inhibition of PDE2 and PDE4 synergistically improves memory consolidation processes | Neuropharmacology | Dean Paes Keqiang Xie Damian G Wheeler Douglas Zook Jos Prickaerts | 2021/2/15 |
PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity | Ben Rombaut Sofie Kessels Melissa Schepers Assia Tiane Dean Paes | 2021 |
