dean fennell

dean fennell

University of Leicester

H-index: 61

Europe-United Kingdom

About dean fennell

dean fennell, With an exceptional h-index of 61 and a recent h-index of 45 (since 2020), a distinguished researcher at University of Leicester, specializes in the field of mesothelioma.

His recent articles reflect a diverse array of research interests and contributions to the field:

First-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 triggers mesenchymal-to-epithelial transition in mesothelioma

ASTX295 engages p53-mediated apoptosis and an inflammatory response in patient derived mesothelioma explants

208 SynthEtic LEthal Cancer Therapy in mesothelioma (SELECTmeso): a molecularly stratified multi-arm phase II platform trial for patients with relapsed malignant mesothelioma

The IASLC Mesothelioma Staging Project: Proposals for Revisions of the ‘T’Descriptors in the Forthcoming 9th Edition of the TNM Classification for Pleural Mesothelioma

61 The first-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 modulates the mesenchymal and immune phenotype in mesothelioma

Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial

The IASLC Lung Cancer Staging Project: Proposals for Revision of the Classification of Residual Tumor after Resection for the Forthcoming (9th) Edition of the TNM …

Gene fusions during the early evolution of mesothelioma correlate with impaired DNA repair and Hippo pathways

dean fennell Information

University

Position

___

Citations(all)

18538

Citations(since 2020)

11791

Cited By

11404

hIndex(all)

61

hIndex(since 2020)

45

i10Index(all)

153

i10Index(since 2020)

117

Email

University Profile Page

University of Leicester

Google Scholar

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dean fennell Skills & Research Interests

mesothelioma

Top articles of dean fennell

Title

Journal

Author(s)

Publication Date

First-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 triggers mesenchymal-to-epithelial transition in mesothelioma

Cancer Research

Terri Messier

Victoria Gibson

David J Seward

Essa Y Baitei

Peter Wells Jordan

...

2024/3/22

ASTX295 engages p53-mediated apoptosis and an inflammatory response in patient derived mesothelioma explants

Cancer Research

Dean Anthony Fennell

Joanna Dzialo

Jan Rogel

Daniel Faulkner

Nada Nusrat

...

2024/3/22

208 SynthEtic LEthal Cancer Therapy in mesothelioma (SELECTmeso): a molecularly stratified multi-arm phase II platform trial for patients with relapsed malignant mesothelioma

Lung Cancer

Kayleigh Hill

Dean Fennell

Anna Song

Robin Wickens

Judith Cave

...

2024/4/1

The IASLC Mesothelioma Staging Project: Proposals for Revisions of the ‘T’Descriptors in the Forthcoming 9th Edition of the TNM Classification for Pleural Mesothelioma

Journal of thoracic oncology

Anna K Nowak

Kari Chansky

David C Rice

Harvey I Pass

Hedy L Kindler

...

2016/12/1

61 The first-in-class peroxiredoxin 3 (PRX3) inhibitor RSO-021 modulates the mesenchymal and immune phenotype in mesothelioma

Lung Cancer

Brian Cunniff

Terri Messier

Victoria Gibson

David Seward

Essa Baitei

...

2024/4/1

Pegargiminase Plus First-Line Chemotherapy in Patients With Nonepithelioid Pleural Mesothelioma: The ATOMIC-Meso Randomized Clinical Trial

JAMA oncology

Peter W Szlosarek

Benjamin C Creelan

Thomas Sarkodie

Luke Nolan

Paul Taylor

...

2024/2/15

The IASLC Lung Cancer Staging Project: Proposals for Revision of the Classification of Residual Tumor after Resection for the Forthcoming (9th) Edition of the TNM …

William D Travis

Hisao Asamura

Alexander A Bankier

Mary Beth Beasley

Frank Detterbeck

...

2016/8/1

Gene fusions during the early evolution of mesothelioma correlate with impaired DNA repair and Hippo pathways

Genes, Chromosomes and Cancer

Maymun Jama

Min Zhang

Charlotte Poile

Apostolos Nakas

Annabel Sharkey

...

2024/1

SLC7A11 modulates sensitivity to the first-in-class mitochondrial peroxiredoxin 3 inhibitor thiostrepton (RSO-021) via a ferroptosis independent pathway

Cancer Research

Terri Messier

Victoria Gibson

Aleksandra Bzura

Joanna Dzialo

Charlotte Poile

...

2024/3/22

Effects of RSO-021 on cytokine profiles of malignant pleural effusions from patients enrolled in the MITOPE phase 1/2 clinical trial

Terri Messier

Molly Scotland

George Naumov

Sean Dulloo

Dean Fennell

...

2023/12/1

The evolution of lung cancer and impact of subclonal selection in TRACERx

Nature

Charles Swanton

Nicholas McGranahan

Mariam Jamal-Hanjani

Alexander M Frankell

Michelle Dietzen

...

2023/4/20

Efficacy, cellular and molecular determinants of PD-1 checkpoint inhibition in relapsed mesothelioma.

Dean Anthony Fennell

Sean Ewings

Kayleigh Hill

Charlotte Poile

Essa Baitei

...

2023/6/1

BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms

Oncogene

Anita Singh

Sara Busacca

Aarti Gaba

Michael Sheaff

Charlotte Poile

...

2023/2/17

OA02. 05 Dendritic Cell Immunotherapy Versus Best Supportive Care as Maintenance Treatment in Patients with Pleural Mesothelioma

Journal of Thoracic Oncology

JGJV Aerts

B Belderbos

P Baas

A Scherpereel

R Berardi

...

2023/11/1

Abstract C027: RSO-021, a first-in-class covalent inhibitor of mitochondrial PRX3: From bench to bedside

Dean A Fennell

Sean Dulloo

Peter Szlosarek

Fiona Thistlethwaite

Simon Lord

...

2023/12/1

Bemcentinib and pembrolizumab in patients with relapsed mesothelioma: MIST3, a phase IIa trial with cellular and molecular correlates of efficacy.

Matthew G Krebs

Amy Branson

Shaun Barber

Charlotte Poile

Amy King

...

2023/6/1

The evolution of non-small cell lung cancer metastases in TRACERx

Nature

Maise Al Bakir

Ariana Huebner

Carlos Martínez-Ruiz

Kristiana Grigoriadis

Thomas BK Watkins

...

2023/4/20

Protocol: Evaluating niraparib versus active symptom control in patients with previously treated mesothelioma (NERO): a study protocol for a multicentre, randomised, two-arm …

BMJ Open

Dean Fennell

Daniel Griffiths

Zina Eminton

Abigail Morgan-Fox

Kayleigh Hill

...

2023

P2. 18-02 Successful Generation of Tumor-Infiltrating Lymphocytes (TIL) for Adoptive Cell Therapy from Mesothelioma

Journal of Thoracic Oncology

DA Fennell

C Poile

A Bzura

J Dzialo

A Nakas

...

2023/11/1

Abstract B022: Effects of RSO-021 on cytokine profiles of malignant pleural effusions from patients enrolled in the MITOPE phase 1/2 clinical trial

Molecular Cancer Therapeutics

Terri Messier

Molly Scotland

George Naumov

Sean Dulloo

Dean Fennell

...

2023/12/1

See List of Professors in dean fennell University(University of Leicester)