David W. Hein

David W. Hein

University of Louisville

H-index: 67

North America-United States

About David W. Hein

David W. Hein, With an exceptional h-index of 67 and a recent h-index of 24 (since 2020), a distinguished researcher at University of Louisville, specializes in the field of Pharmacogenomics, molecular epidemiology, cancer research.

His recent articles reflect a diverse array of research interests and contributions to the field:

Effect of N-acetyltransferase 2 genetic polymorphism on 4, 4′-methylenebis (2-chloroaniline)-induced genotoxicity and oxidative stress

The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

P13-049-23 N-Acetyltransferase 1 Knockout in Immortalized Human Bronchial Cells Results in a Reduction of Cellular Growth

Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

David W. Hein Information

University

Position

Professor of Pharmacology & Toxicology

Citations(all)

17521

Citations(since 2020)

2435

Cited By

15465

hIndex(all)

67

hIndex(since 2020)

24

i10Index(all)

213

i10Index(since 2020)

69

Email

University Profile Page

University of Louisville

Google Scholar

View Google Scholar Profile

David W. Hein Skills & Research Interests

Pharmacogenomics

molecular epidemiology

cancer research

Top articles of David W. Hein

Title

Journal

Author(s)

Publication Date

Effect of N-acetyltransferase 2 genetic polymorphism on 4, 4′-methylenebis (2-chloroaniline)-induced genotoxicity and oxidative stress

Archives of Toxicology

Mariam R Habil

Raúl A Salazar-González

Mark A Doll

David W Hein

2023/5/4

The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure

Archives of Toxicology

David W Hein

Raúl A Salazar-González

Mark A Doll

Yu Zang

2023/10

Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity

Archives of Toxicology

Mariam R Habil

David W Hein

2023/4/25

N-acetyltransferase 2 haplotype modifies risks for both dyslipidemia and urinary bladder cancer

Pharmacogenetics and Genomics

Kyung U Hong

David W Hein

2023/8/1

Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

Archives of Toxicology

Kennedy M Walls

Kyung U Hong

David W Hein

2023/4/2

P13-049-23 N-Acetyltransferase 1 Knockout in Immortalized Human Bronchial Cells Results in a Reduction of Cellular Growth

Current Developments in Nutrition

James Wise

Kate Tarvestad-Laise

Sandra Wise

David Hein

2023/7/1

Stable Isotope Tracing Reveals an Altered Fate of Glucose in N-Acetyltransferase 1 Knockout Breast Cancer Cells

Genes

James TF Wise

Xinmin Yin

Xipeng Ma

Xiang Zhang

David W Hein

2023/3/31

Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes

Toxicology Letters

Kennedy M Walls

Kyung U Hong

David W Hein

2023/7/1

Non-coding and intergenic genetic variants of human arylamine N-acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and …

Kyung U Hong

Kennedy M Walls

David W Hein

2023

Upregulation of cytidine deaminase in NAT1 knockout breast cancer cells

Journal of Cancer Research and Clinical Oncology

Kyung U Hong

Afi H Tagnedji

Mark A Doll

Kennedy M Walls

David W Hein

2023/7

Correction: Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes

Archives of toxicology

Kennedy M Walls

Kyung U Hong

David W Hein

2023/11

N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

Archives of toxicology

Raúl A Salazar-González

Mark A Doll

David W Hein

2023/1

560G> A (rs4986782)(R187Q) single nucleotide polymorphism in arylamine N-acetyltransferase 1 increases affinity for the aromatic amine carcinogens 4-aminobiphenyl and N-hydroxy …

Frontiers in Pharmacology

David W Hein

Mark A Doll

2022

Expression of arylamine N-acetyltransferase 2 activity in immortalized human bronchial epithelial cells

Toxicology and applied pharmacology

James TF Wise

Raúl A Salazar-González

Mariam R Habil

Mark A Doll

David W Hein

2022/5/1

Association between cigarette smoking and ovarian reserve among women seeking fertility care

Plos one

Islamiat Oladipupo

T’shura Ali

David W Hein

Kelly Pagidas

Henry Bohler

...

2022/12/13

Acetyl coenzyme A kinetic studies on N-acetylation of environmental carcinogens by human N-acetyltransferase 1 and its NAT1* 14B variant

Frontiers in Pharmacology

Mariam R Habil

Mark A Doll

David W Hein

2022/10/28

Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens

Frontiers in Pharmacology

David W Hein

Mark A Doll

Mariam R Habil

2022

Deletion of arylamine N‐acetyltransferase 1 in MDA‐MB‐231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant …

Molecular carcinogenesis

Mark A Doll

Andrew R Ray

Raúl A Salazar‐González

Parag P Shah

Alexis A Vega

...

2022/5

Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells

Toxicology and applied pharmacology

James TF Wise

Raúl A Salazar-González

Kennedy M Walls

Mark A Doll

Mariam R Habil

...

2022/8/15

Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines

Toxicological Sciences

Kyung U Hong

Raúl A Salazar-González

Kennedy M Walls

David W Hein

2022/12/1

See List of Professors in David W. Hein University(University of Louisville)

Co-Authors

H-index: 170
Wei Zheng

Wei Zheng

Vanderbilt University

H-index: 65
edith sim

edith sim

University of Oxford

H-index: 64
WM Pierce

WM Pierce

University of Louisville

H-index: 40
J Christopher States

J Christopher States

University of Louisville

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