David Vocadlo
Simon Fraser University
H-index: 66
North America-Canada
Top articles of David Vocadlo
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2 | bioRxiv | Adriano Aguzzi Jiang-An Yin David J Vocadlo Kathi Ging Frick Lukas | 2024 |
Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic … | bioRxiv | Darian Williams Logan M Glasstetter Tiffany T Jong Abhijeet Kapoor Sha Zhu | 2024 |
Suggested searches | Perspective | Sunkyung Kim Jing Chen Feiya Ou Tian-Tian Liu Suin Jo | 2024/3/4 |
Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism | Angewandte Chemie International Edition | Matthew G Alteen Hayden Peacock Richard W Meek Jil A Busmann Sha Zhu | 2023/1/26 |
Targeting neuronal lysosomal dysfunction caused by β-glucocerebrosidase deficiency with an enzyme-based brain shuttle construct | Nature communications | Alexandra Gehrlein Vinod Udayar Nadia Anastasi Martino L Morella Iris Ruf | 2023/4/12 |
Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons | Eneuro | AJ Keefe DR Gabrych Y Zhu DJ Vocadlo MA Silverman | 2023/10/1 |
Non-lysosomal glucosylceramidase inhibitors and uses thereof | 2023/11/2 | ||
Genetic modulation of protein O-GlcNAcylation affects Atrial Fibrillation susceptibility | Journal of Biological Chemistry | Olurotimi Mesubi Jonathan Granger Pauline Nguyen David Vocadlo Natasha Zachara | 2023/1/1 |
HBP/O-GlcNAcylation metabolic axis regulates bone resorption outcome | Journal of Dental Research | TM Taira ES Ramos-Junior PH Melo CC Costa-Silva MG Alteen | 2023/4 |
Potent and Selective Cell‐Active Iminosugar Inhibitors of Human α‐N‐Acetylgalactosaminidase (α‐NAGAL) | Chemistry–A European Journal | Roger A Ashmus Yang Wang Manuel González‐Cuesta Dustin T King Ben Tiet | 2023/8/4 |
Inhibitors of protein fucosylation and uses thereof | 2023/10/19 | ||
In Situ Imaging of O-Linked β-N-Acetylglucosamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry | Cancers | Edwin E Escobar Erin H Seeley Jesús E Serrano-Negrón David J Vocadlo Jennifer S Brodbelt | 2023/2/15 |
Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase | Proceedings of the National Academy of Sciences | Matthew G Alteen Richard W Meek Subramania Kolappan Jil A Busmann Jessica Cao | 2023/10/17 |
A Fluorogenic Disaccharide Substrate for α-Mannosidases Enables High-Throughput Screening and Identification of an Inhibitor of the GH92 Virulence Factor from Streptococcus … | ACS Chemical Biology | Sandeep Bhosale Matthew C Deen Cameron Proceviat Andrew Hettle Dana K Winter | 2023/8/2 |
Glycosidase inhibitors and uses thereof | 2023/12/7 | ||
Synthesis of Uronic Acid 1‐Azasugars as Putative Inhibitors of α‐Iduronidase, β‐Glucuronidase and Heparanase | ChemBioChem | Gareth G Doherty Geraldine Jia Ming Ler Norbert Wimmer Paul V Bernhardt Roger A Ashmus | 2023/2/14 |
Altered Tau Kinase Activity in rTg4510 Mice after a Single Interfaced CHIMERA Traumatic Brain Injury | International Journal of Molecular Sciences | Wai Hang Cheng Honor Cheung Amy Kang Jianjia Fan Jennifer Cooper | 2023/5/29 |
Human O-GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics | ACS catalysis | Martín Calvelo Alexandra Males Matthew G Alteen Lianne I Willems David J Vocadlo | 2023/10/10 |
Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases | Matthew R Pratt David J Vocadlo | 2023/12/1 | |
Conformationally responsive dyes enable protein-adaptive differential scanning fluorimetry | bioRxiv | Taiasean Wu C Yu Joshua Arundhati Suresh Zachary J Gale-Day Matthew G Alteen | 2023/1/28 |
