David Spafford

David Spafford

University of Waterloo

H-index: 25

North America-Canada

About David Spafford

David Spafford, With an exceptional h-index of 25 and a recent h-index of 12 (since 2020), a distinguished researcher at University of Waterloo, specializes in the field of ion channels, calcium channels, neuroscience, NALCN, sodium channels.

His recent articles reflect a diverse array of research interests and contributions to the field:

Electrical and calcium signaling of nerve and muscle in unicellular choanoflagellates

A governance of ion selectivity based on the occupancy of the “beacon” in one-and four-domain calcium and sodium channels

A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions

Voltage-gated calcium channels in invertebrates

Asynchronous delivery of a 400 level, partially peer-graded, oral presentation and discussion course in systems neuroscience for 60 students during the COVID-19 pandemic

Unicellular CaVβ Subunit Modulates Calcium Channels

An ancestral MAGUK protein supports the modulation of mammalian voltage-gated Ca2+ channels through a conserved CaVβ–like interface

Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in CaV3 T-type channels alter the passage and block of monovalent and divalent ions

David Spafford Information

University

Position

Associate Professor of Biology

Citations(all)

1570

Citations(since 2020)

388

Cited By

1363

hIndex(all)

25

hIndex(since 2020)

12

i10Index(all)

33

i10Index(since 2020)

15

Email

University Profile Page

University of Waterloo

Google Scholar

View Google Scholar Profile

David Spafford Skills & Research Interests

ion channels

calcium channels

neuroscience

NALCN

sodium channels

Top articles of David Spafford

Title

Journal

Author(s)

Publication Date

Electrical and calcium signaling of nerve and muscle in unicellular choanoflagellates

Biophysical Journal

J David Spafford

Amrit Mehta

Shazah Waqar

Prashanth S Velayudhan

Jonathan Fan

...

2024/2/8

A governance of ion selectivity based on the occupancy of the “beacon” in one-and four-domain calcium and sodium channels

J David Spafford

2023/12/31

A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions

Journal of Biological Chemistry

Wendy Guan

Kaidy G Orellana

Robert F Stephens

Boris S Zhorov

J David Spafford

2022/12/1

Voltage-gated calcium channels in invertebrates

Adriano Senatore

J David Spafford

2022/11/8

Asynchronous delivery of a 400 level, partially peer-graded, oral presentation and discussion course in systems neuroscience for 60 students during the COVID-19 pandemic

Brain Sciences

Jack Moffat

Charlotte Copas

Kate Wood

J David Spafford

2021/5/25

Unicellular CaVβ Subunit Modulates Calcium Channels

Biophysical Journal

Emilie Segura

Amrit Mehta

Mireille Marsolais

Xuan R Quan

Juan Zhao

...

2020/2/7

An ancestral MAGUK protein supports the modulation of mammalian voltage-gated Ca2+ channels through a conserved CaVβ–like interface

Biochimica et Biophysica Acta (BBA)-Biomembranes

Emilie Segura

Amrit Mehta

Mireille Marsolais

Xin R Quan

Juan Zhao

...

2020/11/1

Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in CaV3 T-type channels alter the passage and block of monovalent and divalent ions

Scientific Reports

Wendy Guan

Robert F Stephens

Omar Mourad

Amrit Mehta

Julia Fux

...

2020/7/24

See List of Professors in David Spafford University(University of Waterloo)