David Needham
Duke University
H-index: 71
North America-United States
Top articles of David Needham
Title | Journal | Author(s) | Publication Date |
|---|---|---|---|
Niclosamide: A career builder | Journal of Controlled Release | David Needham | 2024/3/21 |
Extraction of niclosamide from commercial approved tablets into aqueous buffered solution creates potentially approvable oral and nasal sprays against COVID-19 and other … | Aaps Open | David Needham | 2023/4/14 |
LPS-aggregating proteins GBP1 and GBP2 are each sufficient to enhance caspase-4 activation both in cellulo and in vitro | Proceedings of the National Academy of Sciences | Mary S Dickinson Miriam Kutsch Linda Sistemich Dulcemaria Hernandez Anthony S Piro | 2023/4/11 |
Low-Density Lipoprotein Pathway Is a Ubiquitous Metabolic Vulnerability in High Grade Glioma Amenable for Nanotherapeutic Delivery | Pharmaceutics | Adenike O Adekeye David Needham Ruman Rahman | 2023/2/10 |
Niclosamide nasal and throat spray | 2023/12/28 | ||
GBP2 aggregates LPS and activates the caspase-4 inflammasome independent of the bacterial encapsulation factor GBP1 | Biorxiv | Mary S Dickinson Miriam Kutsch Linda Sistemich Dulcemaria Hernandez Anthony S Piro | 2022/10/7 |
The PH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, Its … | Pharmaceutical research | David Needham | 2022/1 |
Chemical modulators of signaling pathways and therapeutic use | 2021/2/2 | ||
Designing topographically textured microparticles for induction and modulation of osteogenesis in mesenchymal stem cell engineering | Biomaterials | Mahetab H Amer Marta Alvarez-Paino Jane McLaren Francesco Pappalardo Sara Trujillo | 2021/1/1 |
Inhibition of the futalosine pathway for menaquinone biosynthesis suppresses Chlamydia trachomatis infection | FEBS letters | Brianne M Dudiak Tri M Nguyen David Needham Taylor C Outlaw Dewey G McCafferty | 2021/12 |
Investigation of the futalosine pathway for menaquinone biosynthesis as a novel target in the inhibition of Chlamydia trachomatis infection | bioRxiv | Brianne M Dudiak Tri M Nguyen David Needham Taylor C Outlaw Dewey G McCafferty | 2021/10/27 |
Preclinical testing of a novel niclosamide stearate prodrug therapeutic (NSPT) shows efficacy against osteosarcoma | Molecular cancer therapeutics | Gireesh B Reddy David L Kerr Ivan Spasojevic Artak Tovmasyan David S Hsu | 2020/7/1 |
Development of clinically effective formulations for anticancer applications: why it is so difficult? | David Needham | 2020/1/1 |
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