David Kirsch

David Kirsch

Duke University

H-index: 69

North America-United States

About David Kirsch

David Kirsch, With an exceptional h-index of 69 and a recent h-index of 49 (since 2020), a distinguished researcher at Duke University,

His recent articles reflect a diverse array of research interests and contributions to the field:

Radiotherapy Combined with Intralesional Immunostimulatory Agents for Soft Tissue Sarcomas

Preclinical Evaluation of the ATR Inhibitor BAY 1895344 as a Radiosensitizer for Head and Neck Squamous Cell Carcinoma

Spontaneous expression of the CIC:: DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice

A novel dual ATM/DNA-PK inhibitor, XRD-0394, potently radiosensitizes and potentiates PARP and topoisomerase I inhibitors

The next chapter in immunotherapy and radiation combination therapy–cancer-specific perspectives

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma

Abstract LB181: First disclosure of XRD-0394, a novel dual ATM/DNA-PK inhibitor, that potently radiosensitizes and potentiates PARP and topoisomerase inhibitors

David Kirsch Information

University

Position

___

Citations(all)

20210

Citations(since 2020)

8672

Cited By

14871

hIndex(all)

69

hIndex(since 2020)

49

i10Index(all)

184

i10Index(since 2020)

153

Email

University Profile Page

Duke University

Google Scholar

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Top articles of David Kirsch

Title

Journal

Author(s)

Publication Date

Radiotherapy Combined with Intralesional Immunostimulatory Agents for Soft Tissue Sarcomas

Chang Su

Soo Kyoung Kim

Charles X Wang

David G Kirsch

Arta M Monjazeb

2024/4/1

Preclinical Evaluation of the ATR Inhibitor BAY 1895344 as a Radiosensitizer for Head and Neck Squamous Cell Carcinoma

International Journal of Radiation Oncology* Biology* Physics

Diana A Odhiambo

Allison N Pittman

Ashlyn G Rickard

Rico J Castillo

Alex M Bassil

...

2024/4/1

Spontaneous expression of the CIC:: DUX4 fusion oncoprotein from a conditional allele potently drives sarcoma formation in genetically engineered mice

Oncogene

Peter G Hendrickson

Kristianne M Oristian

MaKenna R Browne

Lixia Luo

Yan Ma

...

2024/2/27

A novel dual ATM/DNA-PK inhibitor, XRD-0394, potently radiosensitizes and potentiates PARP and topoisomerase I inhibitors

Molecular Cancer Therapeutics

Tona M Gilmer

Chun-Hsiang Lai

Kexiao Guo

Katherine Deland

Kathleen A Ashcraft

...

2024/4/8

The next chapter in immunotherapy and radiation combination therapy–cancer-specific perspectives

Amy J Wisdom

Christopher A Barker

Joe Y Chang

Sandra Demaria

Silvia Formenti

...

2024/1/5

p53 promotes revival stem cells in the regenerating intestine after severe radiation injury

Nature Communications

Clara Morral

Arshad Ayyaz

Hsuan-Cheng Kuo

Mardi Fink

Ioannis I Verginadis

...

2024/4/8

Enhancing radiotherapy response via intratumoral injection of the TLR9 agonist CpG to stimulate CD8 T cells in an autochthonous mouse model of sarcoma

bioRxiv

Chang Su

Collin L Kent

Matthew Pierpoint

Warren Floyd

Lixia Luo

...

2024/1/4

Abstract LB181: First disclosure of XRD-0394, a novel dual ATM/DNA-PK inhibitor, that potently radiosensitizes and potentiates PARP and topoisomerase inhibitors

Cancer Research

Tona M Gilmer

Chun-Hsiang Lai

Kexiao Guo

Katherine Deland

Kathleen A Ashcraft

...

2024/4/5

Temporary knockdown of p53 during focal limb irradiation increases the development of sarcomas

Cancer Research Communications

Andrea R Daniel

Chang Su

Nerissa T Williams

Zhiguo Li

Jianguo Huang

...

2023/12/5

56Fe ion exposure increases the incidence of lung and brain tumors at a similar rate in male and female mice

bioRxiv

Sophie R Finkelstein

Rutulkumar Patel

Katherine Deland

Joshua Mercer

Bryce Starr

...

2023

Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination

STAR protocols

Loren B Weidenhammer

Harrison Q Liu

Lixia Luo

Nerissa T Williams

Katherine Deland

...

2023/3/17

Pathologic complete response and clinical outcomes in patients with localized soft tissue sarcoma treated with neoadjuvant chemoradiotherapy or radiotherapy: the NRG/RTOG 9514 …

JAMA oncology

Dian Wang

Jonathan Harris

William G Kraybill

Burt Eisenberg

David G Kirsch

...

2023/5/1

Genetically Engineered Mouse Models of CIC-DUX4 Sarcoma Reveal an Unexpected Sensitivity to Histone Deacetylase (HDAC) Inhibition

International Journal of Radiation Oncology, Biology, Physics

P Hendrickson

KM Oristian

L Lou

Y Ma

DM Cardona

...

2023/10/1

Single-fraction Radiation Treatment Dose Response in a Genetically Engineered Mouse Model of Medulloblastoma

Radiation Research

Kevin J Tu

Connor E Stewart

Nerissa T Williams

Yan Ma

Lixia Luo

...

2023/12/1

Relationship between the tumor microenvironment and the efficacy of the combination of radiotherapy and immunotherapy

International review of cell and molecular biology

Chang Su

Jonathon E Himes

David G Kirsch

2023

p53 and RB Cooperate to Suppress Transposable Elements

bioRxiv

Omar M Lopez

Michelle Zhang

Peter G Hendrickson

Jianguo Huang

Andrea R Daniel

...

2023/2/6

Transitioning from a COMS‐based plaque brachytherapy program to using eye physics plaques and plaque simulator treatment planning system: A single institutional experience

Journal of Applied Clinical Medical Physics

Sheridan G Meltsner

Anna Rodrigues

Miguel A Materin

David G Kirsch

Oana Craciunescu

2023/5

Expression of the CIC-DUX4 fusion oncoprotein mimics human CIC-rearranged sarcoma in genetically engineered mouse models

bioRxiv

Peter G Hendrickson

Kristianne M Oristian

MaKenna R Browne

Lixia Lou

Yan Ma

...

2023/9/28

Radiation-induced bone loss in mice is ameliorated by inhibition of HIF-2α in skeletal progenitor cells

Science translational medicine

Wendi Guo

Jiaul Hoque

Carolina J Garcia Garcia

Kassandra V Spiller

Abigail P Leinroth

...

2023/11/29

A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity (SU2C-SARC032)

Annals of surgical oncology

Areeba Saif

Emily A Verbus

Amber Leila Sarvestani

Martha E Teke

Jacob Lambdin

...

2023/2

See List of Professors in David Kirsch University(Duke University)