David J. Segal

David J. Segal

University of California, Davis

H-index: 57

North America-United States

About David J. Segal

David J. Segal, With an exceptional h-index of 57 and a recent h-index of 32 (since 2020), a distinguished researcher at University of California, Davis, specializes in the field of Genome Engineering.

His recent articles reflect a diverse array of research interests and contributions to the field:

CRISPR-Based Split Luciferase as a Biosensor for Unique DNA Sequences In Situ

Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons

Dr. Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements

Unique features of the gut microbiome characterized in animal models of Angelman Syndrome

Animal model of Angelman Syndrome

Split-enzyme system to detect specific dna in living cells

Plant transformation

Screening Cas13 guide RNA to evaluate efficiency and specificity

David J. Segal Information

University

Position

___

Citations(all)

11991

Citations(since 2020)

3837

Cited By

9576

hIndex(all)

57

hIndex(since 2020)

32

i10Index(all)

89

i10Index(since 2020)

70

Email

University Profile Page

University of California, Davis

Google Scholar

View Google Scholar Profile

David J. Segal Skills & Research Interests

Genome Engineering

Top articles of David J. Segal

Title

Journal

Author(s)

Publication Date

CRISPR-Based Split Luciferase as a Biosensor for Unique DNA Sequences In Situ

Nicholas G Heath

David J Segal

2024/3/20

Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons

bioRxiv

Orangel J Gutierrez Fugon

Osman Sharifi

Nicholas G Heath

Daniela C Soto

J Antonio Gomez

...

2024

Dr. Nod: computational framework for discovery of regulatory non-coding drivers in tissue-matched distal regulatory elements

Nucleic Acids Research

Marketa Tomkova

Jakub Tomek

Julie Chow

John D McPherson

David J Segal

...

2023/2/28

Unique features of the gut microbiome characterized in animal models of Angelman Syndrome

Msystems

Ulrika Beitnere

Brayan Vilanova-Cuevas

Sarah G Christian

Clint Taylor

Elizabeth L Berg

...

2023/2/23

Animal model of Angelman Syndrome

2023/10/24

Split-enzyme system to detect specific dna in living cells

2023/2/2

Plant transformation

2004/12/30

Screening Cas13 guide RNA to evaluate efficiency and specificity

Journal of Biological Chemistry

Easwar Kalyan Peddiboina

David Segal

Henriette O'Geen

2023/1/1

Author Correction: Tuning water-use efficiency and drought tolerance in wheat using abscisic acid receptors

Nature Plants

Ryosuke Mega

Fumitaka Abe

June-Sik Kim

Yuuri Tsuboi

Keisuke Tanaka

...

2023/6

Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model

Molecular Therapy

Henriette O’Geen

Ulrika Beitnere

Miranda S Garcia

Anna Adhikari

David L Cameron

...

2023/4/5

The promise of gene editing: so close and yet so perilously far

David J Segal

2022/7/15

Determinants of heritable gene silencing for KRAB-dCas9+ DNMT3 and Ezh2-dCas9+ DNMT3 hit-and-run epigenome editing

Nucleic acids research

Henriette O’Geen

Marketa Tomkova

Jacquelyn A Combs

Emma K Tilley

David J Segal

2022/4/8

Imaging Unique DNA Sequences in Individual Cells Using a CRISPR-Cas9-Based, Split Luciferase Biosensor

Frontiers in Genome Editing

Nicholas G Heath

Henriette O’Geen

Nicole B Halmai

Jacob E Corn

David J Segal

2022/3/25

An in vivo cell-based delivery platform for zinc finger artificial transcription factors in pre-clinical animal models

Frontiers in Molecular Neuroscience

Peter Deng

Julian ANM Halmai

Ulrika Beitnere

David Cameron

Michele L Martinez

...

2022/1/27

Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer

British Journal of Cancer

Maxine Umeh-Garcia

Henriette O’Geen

Catalina Simion

Melanie Hayden Gephart

David J Segal

...

2022/8/1

Scarless genome editing reveals risk SNP rs6983267-G and lncRNA CCAT2 dictate targetable PI3K signaling dependence in WNT-dysregulated CRC

Nicole B Coggins

Henriette O’Geen

Paul C Lott

David J Segal

Luis Carvajal Carmona

2021/7/1

Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells

Human molecular genetics

Anna Adhikari

Nycole A Copping

Julie Beegle

David L Cameron

Peter Deng

...

2021/6/15

The NIH somatic cell genome editing program

Krishanu Saha

Erik J Sontheimer

PJ Brooks

Melinda R Dwinell

Charles A Gersbach

...

2021/4/8

Early developmental EEG and seizure phenotypes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome

eneuro

Heather A Born

Luis A Martinez

Amber T Levine

Sarah E Harris

Shubhangi Mehra

...

2021/3/1

Excessive laughter-like vocalizations, microcephaly, and translational outcomes in the Ube3a deletion rat model of Angelman syndrome

Journal of Neuroscience

Elizabeth L Berg

Shekib A Jami

Stela P Petkova

Annuska Berz

Timothy A Fenton

...

2021/10/20

See List of Professors in David J. Segal University(University of California, Davis)